| In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling PJ Boersema, LY Foong, VMY Ding, S Lemeer, B van Breukelen, R Philp, ... Molecular & Cellular Proteomics 9 (1), 84-99, 2010 | 205 | 2010 |
| Highly Robust, Automated, and Sensitive Online TiO2-Based Phosphoproteomics Applied To Study Endogenous Phosphorylation in Drosophila melanogaster MWH Pinkse, S Mohammed, JW Gouw, B van Breukelen, HR Vos, ... Journal of proteome research 7 (2), 687-697, 2008 | 205 | 2008 |
| Current challenges in software solutions for mass spectrometry-based quantitative proteomics S Cappadona, PR Baker, PR Cutillas, AJR Heck, B van Breukelen Amino acids 43, 1087-1108, 2012 | 148 | 2012 |
| Profiling of N-acetylated protein termini provides in-depth insights into the N-terminal nature of the proteome AO Helbig, S Gauci, R Raijmakers, B van Breukelen, M Slijper, ... Molecular & Cellular Proteomics 9 (5), 928-939, 2010 | 148 | 2010 |
| Quantitative proteomics and transcriptomics of anaerobic and aerobic yeast cultures reveals post-transcriptional regulation of key cellular processes MJL de Groot, P Daran-Lapujade, B van Breukelen, TA Knijnenburg, ... Microbiology 153 (11), 3864-3878, 2007 | 145 | 2007 |
| Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and … A Scholten, MK Poh, TAB van Veen, B van Breukelen, MA Vos, AJR Heck Journal of proteome research 5 (6), 1435-1447, 2006 | 139 | 2006 |
| Quantitative and qualitative proteome characteristics extracted from in-depth integrated genomics and proteomics analysis TY Low, S van Heesch, H van den Toorn, P Giansanti, A Cristobal, ... Cell reports 5 (5), 1469-1478, 2013 | 136 | 2013 |
| The PRoteomics IDEntification (PRIDE) Converter 2 framework: an improved suite of tools to facilitate data submission to the PRIDE database and the ProteomeXchange consortium RG Côté, J Griss, JA Dianes, R Wang, JC Wright, HWP van den Toorn, ... Molecular & Cellular Proteomics 11 (12), 1682-1689, 2012 | 112 | 2012 |
| Targeted analysis of protein termini W Dormeyer, S Mohammed, B Breukelen, J Krijgsveld, AJR Heck Journal of proteome research 6 (12), 4634-4645, 2007 | 112 | 2007 |
| Protease bias in absolute protein quantitation M Peng, N Taouatas, S Cappadona, B Van Breukelen, S Mohammed, ... Nature methods 9 (6), 524-525, 2012 | 110 | 2012 |
| The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication TH Stracker, GD Cassell, P Ward, YM Loo, B Van Breukelen, ... Journal of virology 78 (1), 441-453, 2004 | 109 | 2004 |
| An augmented multiple-protease-based human phosphopeptide atlas P Giansanti, TT Aye, H van den Toorn, M Peng, B van Breukelen, ... Cell reports 11 (11), 1834-1843, 2015 | 108 | 2015 |
| Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels AO Helbig, S Rosati, PWWM Pijnappel, B van Breukelen, MHTH Timmers, ... BMC genomics 11, 1-15, 2010 | 105 | 2010 |
| Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra EL de Graaf, AFM Altelaar, B van Breukelen, S Mohammed, AJR Heck Journal of proteome research 10 (9), 4334-4341, 2011 | 101 | 2011 |
| Daily rhythms in the cyanobacterium Synechococcus elongatus probed by high-resolution mass spectrometry–based proteomics reveals a small defined set of cyclic proteins ACL Guerreiro, M Benevento, R Lehmann, B van Breukelen, H Post, ... Molecular & cellular proteomics 13 (8), 2042-2055, 2014 | 95 | 2014 |
| Facilitating protein disulfide mapping by a combination of pepsin digestion, electron transfer higher energy dissociation (EThcD), and a dedicated search algorithm SlinkS F Liu, B van Breukelen, AJR Heck Molecular & Cellular Proteomics 13 (10), 2776-2786, 2014 | 93 | 2014 |
| Comparative phosphoproteomics reveals evolutionary and functional conservation of phosphorylation across eukaryotes J Boekhorst, B van Breukelen, AJR Heck, B Snel Genome biology 9, 1-9, 2008 | 88 | 2008 |
| Online Automated in Vivo Zebrafish Phosphoproteomics: From Large-Scale Analysis Down to a Single Embryo S Lemeer, MWH Pinkse, S Mohammed, B van Breukelen, J den Hertog, ... Journal of proteome research 7 (4), 1555-1564, 2008 | 88 | 2008 |
| ROCK 1 is a potential combinatorial drug target for BRAF mutant melanoma MA Smit, G Maddalo, K Greig, LM Raaijmakers, PA Possik, ... Molecular systems biology 10 (12), 772, 2014 | 66 | 2014 |
| A versatile peptide pI calculator for phosphorylated and N‐terminal acetylated peptides experimentally tested using peptide isoelectric focusing S Gauci, B Van Breukelen, SM Lemeer, J Krijgsveld, AJR Heck Proteomics 8 (23‐24), 4898-4906, 2008 | 61 | 2008 |
Albert J. R. HeckBiomolecular Mass Spectrometry and Proteomics, Bijvoet Center and Utrecht UniversityVerifierad e-postadress på uu.nl