Lucio Freitas Junior

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Carolina Borsoi MoraesDepartment of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University ofVerifierad e-postadress på usp.br
Jair L. Siqueira-NetoAssociate ProfessorVerifierad e-postadress på health.ucsd.edu
Artur ScherfInstitut PasteurVerifierad e-postadress på pasteur.fr
Eric ChatelainHead of Drug Discovery, Drugs for Neglected Diseases initiativeVerifierad e-postadress på dndi.org
Caio Haddad FrancoAssistant Doctoral ResearcherVerifierad e-postadress på accelbio.pt
Auguste GenovesioEcole Normale SupérieureVerifierad e-postadress på ens.psl.eu
Michael Adsetts Edberg HansenVerifierad e-postadress på vidi.dk
MARIA ISABEL NOGUEIRA CANOUniversidade Estadual PaulistaVerifierad e-postadress på unesp.br
Bruno dos Santos PascoalinoVanderbilt University Medical CenterVerifierad e-postadress på vanderbilt.edu
Wim DegravePesquisador Titular, Instituto Oswaldo Cruz, FiocruzVerifierad e-postadress på fiocruz.br
Alan F. CowmanThe Walter and Eliza Hall Institute of Medical ResearchVerifierad e-postadress på wehi.edu.au
Brendan CrabbCEO and Director, Burnet InsituteVerifierad e-postadress på burnet.edu.au
Arina Marina PerezPós doutoradoVerifierad e-postadress på nih.gov
Liliana Mancio SilvaInserm, Institut PasteurVerifierad e-postadress på inserm.fr
Luisa M FigueiredoProfessor, Gulbenkian Institute for Molecular Medicine, University of Lisbon, PortugalVerifierad e-postadress på medicina.ulisboa.pt
Joseli Lannes-VieiraPesquisadora em Saúde Pública, Instituto Oswaldo CruzVerifierad e-postadress på ioc.fiocruz.br
Carolina Horta AndradeProfessor of Medicinal Chemistry, Faculty of Pharmacy, Universidade Federal de GoiasVerifierad e-postadress på ufg.br
Igor C. AlmeidaProfessor, Dept. Biol. Sciences, University of Texas at El PasoVerifierad e-postadress på utep.edu
Alisson M. GontijoFaculdade de Ciências da Universidade de Lisboa and NOVA Medical School, UNL, Portugal.Verifierad e-postadress på ciencias.ulisboa.pt
Stuart A. RalphThe University of MelbourneVerifierad e-postadress på unimelb.edu.au

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Lucio Freitas Junior

Institute of Biomedical Sciences, ICB, University of São Paulo

Verifierad e-postadress på usp.br - Startsida

Drug Discovery Neglected Tropical Diseases Antigenic Variation Neglected Diseases Phenotypic


Titel Sortera efter citat Sortera efter år Sortera efter titel	Citeras av Citeras av	År
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum LH Freitas-Junior, E Bottius, LA Pirrit, KW Deitsch, C Scheidig, F Guinet, ... Nature 407 (6807), 1018-1022, 2000	624	2000
Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites LH Freitas-Junior, R Hernandez-Rivas, SA Ralph, D Montiel-Condado, ... Cell 121 (1), 25-36, 2005	580	2005
Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum MT Duraisingh, TS Voss, AJ Marty, MF Duffy, RT Good, JK Thompson, ... Cell 121 (1), 13-24, 2005	557	2005
In vitro and in vivo experimental models for drug screening and development for Chagas disease AJ Romanha, SL Castro, MNC Soeiro, J Lannes-Vieira, I Ribeiro, ... Memórias do Instituto Oswaldo Cruz 105, 233-238, 2010	398	2010
Visceral leishmaniasis treatment: what do we have, what do we need and how to deliver it? LH Freitas-Junior, E Chatelain, HA Kim, JL Siqueira-Neto International Journal for Parasitology: Drugs and Drug Resistance 2, 11-19, 2012	381	2012
Multitarget drug discovery for tuberculosis and other infectious diseases K Li, LA Schurig-Briccio, X Feng, A Upadhyay, V Pujari, B Lechartier, ... Journal of medicinal chemistry 57 (7), 3126-3139, 2014	276	2014
The mucin-like glycoprotein super-family of Trypanosoma cruzi: structure and biological roles A Acosta-Serrano, IC Almeida, LH Freitas-Junior, N Yoshida, ... Molecular and biochemical parasitology 114 (2), 143-150, 2001	262	2001
Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and … CB Moraes, MA Giardini, H Kim, CH Franco, AM Araujo-Junior, ... Scientific reports 4 (1), 4703, 2014	226	2014
Antileishmanial high-throughput drug screening reveals drug candidates with new scaffolds JL Siqueira-Neto, OR Song, H Oh, JH Sohn, G Yang, J Nam, J Jang, ... PLoS neglected tropical diseases 4 (5), e675, 2010	183	2010
An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages JL Siqueira-Neto, S Moon, J Jang, G Yang, C Lee, HK Moon, E Chatelain, ... PLoS neglected tropical diseases 6 (6), e1671, 2012	179	2012
A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation LM Figueiredo, LH Freitas‐Junior, E Bottius, JC Olivo‐Marin, A Scherf The EMBO journal, 2002	166	2002
A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes RA O'Donnell, LH Freitas‐Junior, PR Preiser, DH Williamson, ... The EMBO journal, 2002	164	2002
Plasmodium telomeres: a pathogen's perspective A Scherf, LM Figueiredo, LH Freitas-Junior Current opinion in microbiology 4 (4), 409-414, 2001	149	2001
Biochemical characterization of proline racemases from the human protozoan parasite Trypanosoma cruzi and definition of putative protein signatures N Chamond, C Grégoire, N Coatnoan, C Rougeot, LH Freitas-Junior, ... Journal of Biological Chemistry 278 (18), 15484-15494, 2003	95	2003
UV-C (254 nm) lethal doses for SARS-CoV-2 CP Sabino, FP Sellera, DF Sales-Medina, RRG Machado, EL Durigon, ... Photodiagnosis and Photodynamic Therapy 32, 101995, 2020	93	2020
An image analysis algorithm for malaria parasite stage classification and viability quantification S Moon, S Lee, H Kim, LH Freitas-Junior, M Kang, L Ayong, MAE Hansen PloS one 8 (4), e61812, 2013	93	2013
Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library BS Pascoalino, G Courtemanche, MT Cordeiro, LHVG Gil, ... F1000Research 5, 2523, 2016	84	2016
Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library DJM Cruz, RM Bonotto, RGB Gomes, CT da Silva, JB Taniguchi, JH No, ... PLoS neglected tropical diseases 7 (10), e2471, 2013	83	2013
Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity JH No, F de Macedo Dossin, Y Zhang, YL Liu, W Zhu, X Feng, JA Yoo, ... Proceedings of the National Academy of Sciences 109 (11), 4058-4063, 2012	80	2012
Possible integration of Trypanosoma cruzi kDNA minicircles into the host cell genome by infection ARL Teixeira, ER Argañaraz, LH Freitas Jr, ZGM Lacava, JM Santana, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 305 (2 …, 1994	77	1994

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