| Cellular signalling of the receptor for advanced glycation end products (RAGE) J Xie, JD Méndez, V Méndez-Valenzuela, MM Aguilar-Hernández Cellular signalling 25 (11), 2185-2197, 2013 | 580 | 2013 |
| mTOR inhibitors in cancer therapy J Xie, X Wang, CG Proud F1000Research 5, 2078, 2016 | 330 | 2016 |
| Trends in advanced glycation end products research in diabetes mellitus and its complications JD Méndez, J Xie, M Aguilar-Hernández, V Méndez-Valenzuela Molecular and cellular biochemistry 341, 33-41, 2010 | 110 | 2010 |
| Eukaryotic elongation factor 2 kinase activity is controlled by multiple inputs from oncogenic signaling X Wang, S Regufe da Mota, R Liu, CE Moore, J Xie, F Lanucara, ... Molecular and cellular biology 34 (22), 4088-4103, 2014 | 107 | 2014 |
| Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2) AD Barlow, J Xie, CE Moore, SC Campbell, JAM Shaw, ML Nicholson, ... Diabetologia 55, 1355-1365, 2012 | 95 | 2012 |
| cAMP inhibits mammalian target of rapamycin complex-1 and-2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity J Xie, GA Ponuwei, CE Moore, GB Willars, AR Tee, TP Herbert Cellular signalling 23 (12), 1927-1935, 2011 | 86 | 2011 |
| The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes J Xie, TP Herbert Cellular and Molecular Life Sciences 69, 1289-1304, 2012 | 84 | 2012 |
| Regulation of the elongation phase of protein synthesis enhances translation accuracy and modulates lifespan J Xie, V de Souza Alves, T von der Haar, L O’Keefe, RV Lenchine, ... Current Biology 29 (5), 737-749. e5, 2019 | 77 | 2019 |
| Signaling crosstalk between the mTOR complexes J Xie, CG Proud Translation 2 (1), e28174, 2014 | 75 | 2014 |
| mTORC1 signalling and eIF4E/4E-BP1 translation initiation factor stoichiometry influence recombinant protein productivity from GS-CHOK1 cells L Jossé, J Xie, CG Proud, CM Smales Biochemical Journal 473 (24), 4651-4664, 2016 | 73 | 2016 |
| Eukaryotic elongation factor 2 kinase (eEF2K) in cancer X Wang, J Xie, CG Proud Cancers 9 (12), 162, 2017 | 71 | 2017 |
| The MAP kinase-interacting kinases regulate cell migration, vimentin expression and eIF4E/CYFIP1 binding. JE Beggs, S Tian, GG Jones, J Xie, V Iadevaia, V Jenei, G Thomas, ... Biochemical Journal, 2015 | 71 | 2015 |
| Crosstalk between mTOR complexes J Xie, CG Proud Nature cell biology 15 (11), 1263-1265, 2013 | 70 | 2013 |
| mTORC1 Plays an Important Role in Skeletal Development by Controlling pre-Osteoblast Differentiation S Fitter, MP Matthews, SK Martin, J Xie, SS Ooi, CR Walkley, ... Molecular and Cellular Biology 37 (7), MCB. 00668-16, 2017 | 62 | 2017 |
| Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic β-cells CEJ Moore, J Xie, E Gomez, TP Herbert Journal of molecular biology 389 (3), 480-494, 2009 | 61 | 2009 |
| Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRAS G13D mutation T Charitou, S Srihari, MA Lynn, MA Jarboui, E Fasterius, M Moldovan, ... British journal of cancer 121 (1), 37-50, 2019 | 57 | 2019 |
| Eukaryotic elongation factor 2 kinase promotes angiogenesis in hepatocellular carcinoma via PI3K/Akt and STAT3 Y Zhou, Y Li, S Xu, J Lu, Z Zhu, S Chen, Y Tan, P He, J Xu, CG Proud, ... International journal of cancer 146 (5), 1383-1395, 2019 | 50 | 2019 |
| Cambogin induces caspase-independent apoptosis through the ROS/JNK pathway and epigenetic regulation in breast cancer cells. K Shen, J Xie, H Wang, H Zhang, M Yu, F Lu, H Tan, H Xu Molecular Cancer Therapeutics 14 (7), 1738-1749, 2015 | 49 | 2015 |
| Molecular susceptibility to glycation and its implication in diabetes mellitus and related diseases JD Méndez, J Xie, M Aguilar-Hernández, V Méndez-Valenzuela Molecular and Cellular Biochemistry 344, 185-193, 2010 | 47 | 2010 |
| Molecular mechanism for the control of eukaryotic elongation factor 2 kinase by pH: role in cancer cell survival J Xie, H Mikolajek, CR Pigott, KJ Hooper, T Mellows, CE Moore, ... Molecular and cellular biology 35 (10), 1805-1824, 2015 | 46 | 2015 |
Christopher ProudDistinguished Fellow, SAHMRIVerifierad e-postadress på sahmri.com