Följ
Kai He, MD, PhD
Kai He, MD, PhD
The Ohio State University James Comprehensive Cancer Center
Verifierad e-postadress på osumc.edu
Titel
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The mechanism of anti–PD-L1 antibody efficacy against PD-L1–negative tumors identifies NK cells expressing PD-L1 as a cytolytic effector
W Dong, X Wu, S Ma, Y Wang, AP Nalin, Z Zhu, J Zhang, DM Benson, ...
Cancer discovery 9 (10), 1422-1437, 2019
2702019
DLL3: an emerging target in small cell lung cancer
DH Owen, MJ Giffin, JM Bailis, MAD Smit, DP Carbone, K He
Journal of hematology & oncology 12, 1-8, 2019
1882019
Tarlatamab, a first-in-class DLL3-targeted bispecific T-cell engager, in recurrent small-cell lung cancer: an open-label, phase I study
L Paz-Ares, S Champiat, WV Lai, H Izumi, R Govindan, M Boyer, ...
Journal of Clinical Oncology 41 (16), 2893-2903, 2023
1682023
Incidence, risk factors, and effect on survival of immune-related adverse events in patients with non–small-cell lung cancer
DH Owen, L Wei, EM Bertino, T Edd, MA Villalona-Calero, K He, ...
Clinical Lung Cancer 19 (6), e893-e900, 2018
1462018
Ataxia telangiectasia and Rad3-related inhibitors and cancer therapy: where we stand
L Mei, J Zhang, K He, J Zhang
Journal of hematology & oncology 12, 1-8, 2019
1362019
Change in neutrophil to lymphocyte ratio during immunotherapy treatment is a non-linear predictor of patient outcomes in advanced cancers
M Li, D Spakowicz, J Burkart, S Patel, M Husain, K He, EM Bertino, ...
Journal of cancer research and clinical oncology 145, 2541-2546, 2019
1082019
Metalloprotease-mediated GH receptor proteolysis and GHBP shedding: determination of extracellular domain stem region cleavage site
X Wang, K He, M Gerhart, Y Huang, J Jiang, RJ Paxton, S Yang, C Lu, ...
Journal of Biological Chemistry 277 (52), 50510-50519, 2002
1072002
Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats
N Fülöp, W Feng, D Xing, K He, LG Nőt, CA Brocks, RB Marchase, ...
Biogerontology 9, 139-151, 2008
1042008
Growth hormone receptor is a target for presenilin-dependent γ-secretase cleavage
JW Cowan, X Wang, R Guan, K He, J Jiang, G Baumann, RA Black, ...
Journal of Biological Chemistry 280 (19), 19331-19342, 2005
1022005
Advances in epigenetic therapeutics with focus on solid tumors
N Jin, TL George, GA Otterson, C Verschraegen, H Wen, D Carbone, ...
Clinical epigenetics 13, 1-27, 2021
862021
The addition of chemotherapy to radiation therapy improves survival in elderly patients with stage III non–small cell lung cancer
ED Miller, JL Fisher, KE Haglund, JC Grecula, M Xu-Welliver, EM Bertino, ...
Journal of Thoracic Oncology 13 (3), 426-435, 2018
832018
Identification of 1, 2, 3, 4, 5, 6-hexabromocyclohexane as a small molecule inhibitor of Jak2 tyrosine kinase autophophorylation
EM Sandberg, X Ma, K He, SJ Frank, DA Ostrov, PP Sayeski
Journal of medicinal chemistry 48 (7), 2526-2533, 2005
772005
Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling
K He, X Wang, J Jiang, R Guan, KE Bernstein, PP Sayeski, SJ Frank
Molecular endocrinology 17 (11), 2211-2227, 2003
752003
A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis
J Jiang, X Wang, K He, X Li, C Chen, PP Sayeski, MJ Waters, SJ Frank
Molecular Endocrinology 18 (12), 2981-2996, 2004
732004
A virtual molecular tumor board to improve efficiency and scalability of delivering precision oncology to physicians and their patients
MJ Pishvaian, EM Blais, RJ Bender, S Rao, SM Boca, V Chung, ...
JAMIA open 2 (4), 505-515, 2019
702019
Janus kinase 2 enhances the stability of the mature growth hormone receptor
K He, K Loesch, JW Cowan, X Li, L Deng, X Wang, J Jiang, SJ Frank
Endocrinology 146 (11), 4755-4765, 2005
652005
Cancer immune checkpoint blockade therapy and its associated autoimmune cardiotoxicity
J Zhang, W Chen, JB Alvarez, K Jia, L Shi, Q Wang, N Zou, K He, H Zhu
Acta Pharmacologica Sinica 39 (11), 1693-1698, 2018
562018
Determinants of growth hormone receptor down-regulation
L Deng, K He, X Wang, N Yang, C Thangavel, J Jiang, SY Fuchs, ...
Molecular endocrinology 21 (7), 1537-1551, 2007
522007
Bone metastases, skeletal-related events, and survival in patients with metastatic non–small cell lung cancer treated with immune checkpoint inhibitors
A Qin, S Zhao, A Miah, L Wei, S Patel, A Johns, M Grogan, EM Bertino, ...
Journal of the National Comprehensive Cancer Network 19 (8), 915-921, 2021
482021
Janus kinase 2 influences growth hormone receptor metalloproteolysis
K Loesch, L Deng, JW Cowan, X Wang, K He, J Jiang, RA Black, SJ Frank
Endocrinology 147 (6), 2839-2849, 2006
462006
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Artiklar 1–20