The mechanism of anti–PD-L1 antibody efficacy against PD-L1–negative tumors identifies NK cells expressing PD-L1 as a cytolytic effector W Dong, X Wu, S Ma, Y Wang, AP Nalin, Z Zhu, J Zhang, DM Benson, ... Cancer discovery 9 (10), 1422-1437, 2019 | 270 | 2019 |
DLL3: an emerging target in small cell lung cancer DH Owen, MJ Giffin, JM Bailis, MAD Smit, DP Carbone, K He Journal of hematology & oncology 12, 1-8, 2019 | 188 | 2019 |
Tarlatamab, a first-in-class DLL3-targeted bispecific T-cell engager, in recurrent small-cell lung cancer: an open-label, phase I study L Paz-Ares, S Champiat, WV Lai, H Izumi, R Govindan, M Boyer, ... Journal of Clinical Oncology 41 (16), 2893-2903, 2023 | 168 | 2023 |
Incidence, risk factors, and effect on survival of immune-related adverse events in patients with non–small-cell lung cancer DH Owen, L Wei, EM Bertino, T Edd, MA Villalona-Calero, K He, ... Clinical Lung Cancer 19 (6), e893-e900, 2018 | 146 | 2018 |
Ataxia telangiectasia and Rad3-related inhibitors and cancer therapy: where we stand L Mei, J Zhang, K He, J Zhang Journal of hematology & oncology 12, 1-8, 2019 | 136 | 2019 |
Change in neutrophil to lymphocyte ratio during immunotherapy treatment is a non-linear predictor of patient outcomes in advanced cancers M Li, D Spakowicz, J Burkart, S Patel, M Husain, K He, EM Bertino, ... Journal of cancer research and clinical oncology 145, 2541-2546, 2019 | 108 | 2019 |
Metalloprotease-mediated GH receptor proteolysis and GHBP shedding: determination of extracellular domain stem region cleavage site X Wang, K He, M Gerhart, Y Huang, J Jiang, RJ Paxton, S Yang, C Lu, ... Journal of Biological Chemistry 277 (52), 50510-50519, 2002 | 107 | 2002 |
Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats N Fülöp, W Feng, D Xing, K He, LG Nőt, CA Brocks, RB Marchase, ... Biogerontology 9, 139-151, 2008 | 104 | 2008 |
Growth hormone receptor is a target for presenilin-dependent γ-secretase cleavage JW Cowan, X Wang, R Guan, K He, J Jiang, G Baumann, RA Black, ... Journal of Biological Chemistry 280 (19), 19331-19342, 2005 | 102 | 2005 |
Advances in epigenetic therapeutics with focus on solid tumors N Jin, TL George, GA Otterson, C Verschraegen, H Wen, D Carbone, ... Clinical epigenetics 13, 1-27, 2021 | 86 | 2021 |
The addition of chemotherapy to radiation therapy improves survival in elderly patients with stage III non–small cell lung cancer ED Miller, JL Fisher, KE Haglund, JC Grecula, M Xu-Welliver, EM Bertino, ... Journal of Thoracic Oncology 13 (3), 426-435, 2018 | 83 | 2018 |
Identification of 1, 2, 3, 4, 5, 6-hexabromocyclohexane as a small molecule inhibitor of Jak2 tyrosine kinase autophophorylation EM Sandberg, X Ma, K He, SJ Frank, DA Ostrov, PP Sayeski Journal of medicinal chemistry 48 (7), 2526-2533, 2005 | 77 | 2005 |
Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling K He, X Wang, J Jiang, R Guan, KE Bernstein, PP Sayeski, SJ Frank Molecular endocrinology 17 (11), 2211-2227, 2003 | 75 | 2003 |
A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis J Jiang, X Wang, K He, X Li, C Chen, PP Sayeski, MJ Waters, SJ Frank Molecular Endocrinology 18 (12), 2981-2996, 2004 | 73 | 2004 |
A virtual molecular tumor board to improve efficiency and scalability of delivering precision oncology to physicians and their patients MJ Pishvaian, EM Blais, RJ Bender, S Rao, SM Boca, V Chung, ... JAMIA open 2 (4), 505-515, 2019 | 70 | 2019 |
Janus kinase 2 enhances the stability of the mature growth hormone receptor K He, K Loesch, JW Cowan, X Li, L Deng, X Wang, J Jiang, SJ Frank Endocrinology 146 (11), 4755-4765, 2005 | 65 | 2005 |
Cancer immune checkpoint blockade therapy and its associated autoimmune cardiotoxicity J Zhang, W Chen, JB Alvarez, K Jia, L Shi, Q Wang, N Zou, K He, H Zhu Acta Pharmacologica Sinica 39 (11), 1693-1698, 2018 | 56 | 2018 |
Determinants of growth hormone receptor down-regulation L Deng, K He, X Wang, N Yang, C Thangavel, J Jiang, SY Fuchs, ... Molecular endocrinology 21 (7), 1537-1551, 2007 | 52 | 2007 |
Bone metastases, skeletal-related events, and survival in patients with metastatic non–small cell lung cancer treated with immune checkpoint inhibitors A Qin, S Zhao, A Miah, L Wei, S Patel, A Johns, M Grogan, EM Bertino, ... Journal of the National Comprehensive Cancer Network 19 (8), 915-921, 2021 | 48 | 2021 |
Janus kinase 2 influences growth hormone receptor metalloproteolysis K Loesch, L Deng, JW Cowan, X Wang, K He, J Jiang, RA Black, SJ Frank Endocrinology 147 (6), 2839-2849, 2006 | 46 | 2006 |