A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 J Hampe, A Franke, P Rosenstiel, A Till, M Teuber, K Huse, M Albrecht, ... Nature genetics 39 (2), 207-211, 2007 | 2383 | 2007 |
Transcriptome and genome sequencing uncovers functional variation in humans T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ... Nature 501 (7468), 506-511, 2013 | 2120 | 2013 |
Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis P Lepage, R Häsler, ME Spehlmann, A Rehman, A Zvirbliene, A Begun, ... Gastroenterology 141 (1), 227-236, 2011 | 722 | 2011 |
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota J Wang, LB Thingholm, J Skiecevičienė, P Rausch, M Kummen, JR Hov, ... Nature genetics 48 (11), 1396-1406, 2016 | 663 | 2016 |
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer A Couturier-Maillard, T Secher, A Rehman, S Normand, A De Arcangelis, ... The Journal of clinical investigation 123 (2), 2013 | 654 | 2013 |
Sarcoidosis is associated with a truncating splice site mutation in BTNL2 R Valentonyte, J Hampe, K Huse, P Rosenstiel, M Albrecht, A Stenzel, ... Nature genetics 37 (4), 357-364, 2005 | 555 | 2005 |
DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery M Ahrens, O Ammerpohl, W von Schönfels, J Kolarova, S Bens, T Itzel, ... Cell metabolism 18 (2), 296-302, 2013 | 553 | 2013 |
Increased tryptophan metabolism is associated with activity of inflammatory bowel diseases S Nikolaus, B Schulte, N Al-Massad, F Thieme, DM Schulte, J Bethge, ... Gastroenterology 153 (6), 1504-1516. e2, 2017 | 509 | 2017 |
G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation C Sina, O Gavrilova, M Förster, A Till, S Derer, F Hildebrand, B Raabe, ... The Journal of Immunology 183 (11), 7514-7522, 2009 | 440 | 2009 |
Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype P Rausch, A Rehman, S Künzel, R Häsler, SJ Ott, S Schreiber, ... Proceedings of the National Academy of Sciences 108 (47), 19030-19035, 2011 | 432 | 2011 |
Nod2 is essential for temporal development of intestinal microbial communities A Rehman, C Sina, O Gavrilova, R Häsler, S Ott, JF Baines, S Schreiber, ... Gut 60 (10), 1354-1362, 2011 | 394 | 2011 |
Effect of predicted protein-truncating genetic variants on the human transcriptome MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ... Science 348 (6235), 666-669, 2015 | 364 | 2015 |
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice A Chalaris, N Adam, C Sina, P Rosenstiel, J Lehmann-Koch, ... Journal of Experimental Medicine 207 (8), 1617-1624, 2010 | 338 | 2010 |
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories PAC 't Hoen, MR Friedländer, J Almlöf, M Sammeth, I Pulyakhina, ... Nature biotechnology 31 (11), 1015-1022, 2013 | 277 | 2013 |
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL) A Franke, T Balschun, C Sina, D Ellinghaus, R Häsler, G Mayr, M Albrecht, ... Nature genetics 42 (4), 292-294, 2010 | 256 | 2010 |
The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10 G Bochenek, R Häsler, NE El Mokhtari, IR König, BG Loos, S Jepsen, ... Human molecular genetics 22 (22), 4516-4527, 2013 | 252 | 2013 |
The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses S Kuenzel, A Till, M Winkler, R Häsler, S Lipinski, S Jung, J Grötzinger, ... The journal of immunology 184 (4), 1990-2000, 2010 | 246 | 2010 |
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays CM Costello, N Mah, R Häsler, P Rosenstiel, GH Waetzig, A Hahn, T Lu, ... PLoS medicine 2 (8), e199, 2005 | 238 | 2005 |
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies D Ellinghaus, H Zhang, S Zeissig, S Lipinski, A Till, T Jiang, B Stade, ... Gastroenterology 145 (2), 339-347, 2013 | 182 | 2013 |
Systematic association mapping identifies NELL1 as a novel IBD disease gene A Franke, J Hampe, P Rosenstiel, C Becker, F Wagner, R Häsler, ... PloS one 2 (8), e691, 2007 | 180 | 2007 |