BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo CC Kuo, HP Hsieh, WY Pan, CP Chen, JP Liou, SJ Lee, YL Chang, ... Cancer research 64 (13), 4621-4628, 2004 | 260 | 2004 |
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa YM Chiang, JY Chang, CC Kuo, CY Chang, YH Kuo Phytochemistry 66 (4), 495-501, 2005 | 259 | 2005 |
Effects of drying and extrusion on colour, chemical composition, antioxidant activities and mitogenic response of spleen lymphocytes of sweet potatoes MC Shih, CC Kuo, W Chiang Food Chemistry 117 (1), 114-121, 2009 | 198 | 2009 |
4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT … HH Chen, YT Chen, YW Huang, HJ Tsai, CC Kuo Free Radical Biology and Medicine 52 (6), 1054-1066, 2012 | 143 | 2012 |
Surface α-enolase promotes extracellular matrix degradation and tumor metastasis and represents a new therapeutic target KC Hsiao, NY Shih, HL Fang, TS Huang, CC Kuo, PY Chu, YM Hung, ... PloS one 8 (7), e69354, 2013 | 138 | 2013 |
Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and-resistant human tumor cells JY Chang, CY Chang, CC Kuo, LT Chen, YS Wein, YH Kuo Molecular Pharmacology 65 (1), 77-84, 2004 | 137 | 2004 |
2,2‘-Diphenyl-1-picrylhydrazyl Radical-Scavenging Active Components from Adlay (Coix lachryma-jobi L. Var. ma-yuen Stapf) Hulls CC Kuo, W Chiang, GP Liu, YL Chien, JY Chang, CK Lee, JM Lo, ... Journal of agricultural and food chemistry 50 (21), 5850-5855, 2002 | 137 | 2002 |
Antagonism of free-radical-induced damage of adlay seed and its antiproliferative effect in human histolytic lymphoma U937 monocytic cells CC Kuo, MC Shih, YH Kuo, W Chiang Journal of agricultural and food chemistry 49 (3), 1564-1570, 2001 | 111 | 2001 |
Scaffold-hopping strategy: synthesis and biological evaluation of 5, 6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents YS Tung, MS Coumar, YS Wu, HY Shiao, JY Chang, JP Liou, P Shukla, ... Journal of medicinal chemistry 54 (8), 3076-3080, 2011 | 107 | 2011 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach YS Wu, MS Coumar, JY Chang, HY Sun, FM Kuo, CC Kuo, YJ Chen, ... Journal of medicinal chemistry 52 (15), 4941-4945, 2009 | 107 | 2009 |
7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents JY Chang, HP Hsieh, CY Chang, KS Hsu, YF Chiang, CM Chen, CC Kuo, ... Journal of medicinal chemistry 49 (23), 6656-6659, 2006 | 107 | 2006 |
Four new 6-nor-5 (6→ 7) abeo-abietane type diterpenes and antitumoral cytotoxic diterpene constituents from the bark of Taiwania cryptomerioides CI Chang, JY Chang, CC Kuo, WY Pan, YH Kuo Planta medica 71 (01), 72-76, 2005 | 103 | 2005 |
Three New Oleanane-Type Triterpenes from Ludwigia o ctovalvis with Cytotoxic Activity against Two Human Cancer Cell Lines CI Chang, CC Kuo, JY Chang, YH Kuo Journal of natural products 67 (1), 91-93, 2004 | 103 | 2004 |
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia … SH Juang, CC Lung, PC Hsu, KS Hsu, YC Li, PC Hong, HS Shiah, ... Molecular cancer therapeutics 6 (1), 193-202, 2007 | 100 | 2007 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors JP Liou, ZY Wu, CC Kuo, CY Chang, PY Lu, CM Chen, HP Hsieh, ... Journal of medicinal chemistry 51 (14), 4351-4355, 2008 | 98 | 2008 |
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors CY Nien, YC Chen, CC Kuo, HP Hsieh, CY Chang, JS Wu, SY Wu, ... Journal of medicinal chemistry 53 (5), 2309-2313, 2010 | 96 | 2010 |
Histone deacetylase inhibition improved cardiac functions with direct antifibrotic activity in heart failure YH Kao, JP Liou, CC Chung, GS Lien, CC Kuo, SA Chen, YJ Chen International journal of cardiology 168 (4), 4178-4183, 2013 | 95 | 2013 |
Suppression of allergic reactions by dehulled adlay in association with the balance of TH1/TH2 cell responses HY Hsu, BF Lin, JY Lin, CC Kuo, W Chiang Journal of Agricultural and Food Chemistry 51 (13), 3763-3769, 2003 | 95 | 2003 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers CHA Cheung, HH Chen, CC Kuo, CY Chang, MS Coumar, HP Hsieh, ... Molecular cancer 8, 1-15, 2009 | 94 | 2009 |
Targeting cathepsin S induces tumor cell autophagy via the EGFR–ERK signaling pathway KL Chen, WSW Chang, CHA Cheung, CC Lin, CC Huang, YN Yang, ... Cancer letters 317 (1), 89-98, 2012 | 91 | 2012 |