| N-Myc drives neuroendocrine prostate cancer initiated from human prostate epithelial cells JK Lee, JW Phillips, BA Smith, JW Park, T Stoyanova, EF McCaffrey, ... Cancer cell 29 (4), 536-547, 2016 | 404 | 2016 |
| Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage JW Park, JK Lee, KM Sheu, L Wang, NG Balanis, K Nguyen, BA Smith, ... Science 362 (6410), 91-95, 2018 | 289 | 2018 |
| Pan-cancer convergence to a small-cell neuroendocrine phenotype that shares susceptibilities with hematological malignancies NG Balanis, KM Sheu, FN Esedebe, SJ Patel, BA Smith, JW Park, ... Cancer cell 36 (1), 17-34. e7, 2019 | 149 | 2019 |
| Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay JW Park, JK Lee, JW Phillips, P Huang, D Cheng, J Huang, ON Witte Proceedings of the National Academy of Sciences 113 (16), 4482-4487, 2016 | 149 | 2016 |
| Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer JK Lee, NJ Bangayan, T Chai, BA Smith, TE Pariva, S Yun, A Vashisht, ... Proceedings of the National Academy of Sciences 115 (19), E4473-E4482, 2018 | 131 | 2018 |
| A human adult stem cell signature marks aggressive variants across epithelial cancers BA Smith, NG Balanis, A Nanjundiah, KM Sheu, BL Tsai, Q Zhang, ... Cell reports 24 (12), 3353-3366. e5, 2018 | 111 | 2018 |
| Low CD38 identifies progenitor-like inflammation-associated luminal cells that can initiate human prostate cancer and predict poor outcome X Liu, TR Grogan, H Hieronymus, T Hashimoto, J Mottahedeh, D Cheng, ... Cell reports 17 (10), 2596-2606, 2016 | 110 | 2016 |
| Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage JW Park, KP Nickel, AD Torres, D Lee, PF Lambert, RJ Kimple Radiotherapy and Oncology 113 (3), 337-344, 2014 | 108 | 2014 |
| Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer JW Park, HC Pitot, K Strati, N Spardy, S Duensing, M Grompe, PF Lambert Cancer research 70 (23), 9959-9968, 2010 | 105 | 2010 |
| FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate JW Park, JK Lee, ON Witte, J Huang Modern Pathology 30 (9), 1262-1272, 2017 | 103 | 2017 |
| Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer Y Li, Y He, W Butler, L Xu, Y Chang, K Lei, H Zhang, Y Zhou, AC Gao, ... Science translational medicine 11 (521), eaax0428, 2019 | 97 | 2019 |
| Targeting RET kinase in neuroendocrine prostate cancer HR VanDeusen, JR Ramroop, KL Morel, SY Bae, AV Sheahan, Z Sychev, ... Molecular Cancer Research 18 (8), 1176-1188, 2020 | 47 | 2020 |
| Requirement of estrogen receptor alpha DNA-binding domain for HPV oncogene-induced cervical carcinogenesis in mice J Son, JW Park, PF Lambert, SH Chung Carcinogenesis 35 (2), 489-496, 2014 | 40 | 2014 |
| High incidence of female reproductive tract cancers in FA-deficient HPV16-transgenic mice correlates with E7’s induction of DNA damage response, an activity mediated by E7’s … JW Park, MK Shin, PF Lambert Oncogene 33 (26), 3383-3391, 2014 | 36 | 2014 |
| Temporal evolution reveals bifurcated lineages in aggressive neuroendocrine small cell prostate cancer trans-differentiation CC Chen, W Tran, K Song, T Sugimoto, MB Obusan, L Wang, KM Sheu, ... Cancer Cell 41 (12), 2066-2082. e9, 2023 | 35 | 2023 |
| High incidence of HPV-associated head and neck cancers in FA deficient mice is associated with E7’s induction of DNA damage through its inactivation of pocket proteins JW Park, MK Shin, HC Pitot, PF Lambert PloS one 8 (9), e75056, 2013 | 34 | 2013 |
| A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes L Wang, BA Smith, NG Balanis, BL Tsai, K Nguyen, MW Cheng, ... Proceedings of the National Academy of Sciences 117 (1), 563-572, 2020 | 32 | 2020 |
| A proteomic approach for unraveling the oncogenic H‐Ras protein networks in NIH/3T3 mouse embryonic fibroblast cells JW Park, S Kim, KJ Lim, RJ Simpson, YS Kim, YY Bahk Proteomics 6 (4), 1175-1186, 2006 | 18 | 2006 |
| A proteomic approach for dissecting H‐Ras signaling networks in NIH/3T3 mouse embryonic fibroblast cells JW Park, S Kim, YY Bahk Proteomics 6 (8), 2433-2443, 2006 | 8 | 2006 |
| Methods for treating small cell neuroendocrine and related cancers TG Graeber, NG Balanis, ON Witte, F ESEDEBE, JW PARK US Patent App. 17/613,881, 2022 | 1 | 2022 |
Randall J. Kimple, M.D. Ph.D.University of WisconsinVerifierad e-postadress på humonc.wisc.edu
