| Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs M Hafner, M Niepel, M Chung, PK Sorger Nature methods 13 (6), 521-527, 2016 | 666 | 2016 |
| The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ... Cell systems 6 (1), 13-24, 2018 | 440 | 2018 |
| LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures Q Duan, C Flynn, M Niepel, M Hafner, JL Muhlich, NF Fernandez, ... Nucleic acids research 42 (W1), W449-W460, 2014 | 344 | 2014 |
| L1000CDS2: LINCS L1000 characteristic direction signatures search engine Q Duan, SP Reid, NR Clark, Z Wang, NF Fernandez, AD Rouillard, ... NPJ Systems Biology and Applications 2, 16015, 2016 | 306 | 2016 |
| Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity M Hafner, CE Mills, K Subramanian, C Chen, M Chung, SA Boswell, ... Cell Chemical Biology, 2019 | 224 | 2019 |
| Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility J Guan, W Zhou, M Hafner, RA Blake, C Chalouni, IP Chen, T De Bruyn, ... Cell 178 (4), 949-963. e18, 2019 | 185 | 2019 |
| Fractional killing arises from cell‐to‐cell variability in overcoming a caspase activity threshold J Roux, M Hafner, S Bandara, JJ Sims, H Hudson, D Chai, PK Sorger Molecular systems biology 11 (5), 803, 2015 | 165 | 2015 |
| Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients J Ma, SH Fong, Y Luo, CJ Bakkenist, JP Shen, S Mourragui, LFA Wessels, ... Nature Cancer 2 (2), 233-244, 2021 | 147 | 2021 |
| A quantitative approach to screen for nephrotoxic compounds in vitro M Adler, S Ramm, M Hafner, JL Muhlich, EM Gottwald, E Weber, A Jaklic, ... Journal of the American Society of Nephrology 27 (4), 1015-1028, 2016 | 140 | 2016 |
| A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell Systems, 2019 | 137 | 2019 |
| Efficient characterization of high-dimensional parameter spaces for systems biology E Zamora-Sillero, M Hafner, A Ibig, J Stelling, A Wagner BMC systems biology 5 (1), 1-22, 2011 | 119 | 2011 |
| Profiles of Basal and Stimulated Receptor Signaling Networks Predict Drug Response in Breast Cancer Lines M Niepel, M Hafner, EA Pace, M Chung, DH Chai, L Zhou, B Schoeberl, ... Science Signaling 6 (294), ra84, 2013 | 112 | 2013 |
| GRcalculator: an online tool for calculating and mining dose–response data NA Clark, M Hafner, M Kouril, EH Williams, JL Muhlich, M Pilarczyk, ... BMC Cancer 17 (1), 698, 2017 | 107 | 2017 |
| An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance TJ Hagenbeek, JR Zbieg, M Hafner, R Mroue, JA Lacap, NM Sodir, ... Nature Cancer 4 (6), 812-828, 2023 | 98 | 2023 |
| Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling M Niepel, M Hafner, Q Duan, Z Wang, EO Paull, M Chung, X Lu, JM Stuart, ... Nature Communications 8 (1), 1186, 2017 | 98 | 2017 |
| ‘Glocal’ robustness analysis and model discrimination for circadian oscillators M Hafner, H Koeppl, M Hasler, A Wagner PLoS computational biology 5 (10), e1000534, 2009 | 96 | 2009 |
| Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics M Hafner, M Niepel, PK Sorger Nature Biotechnology 35 (6), 500-502, 2017 | 88 | 2017 |
| Effect of network architecture on synchronization and entrainment properties of the circadian oscillations in the suprachiasmatic nucleus M Hafner, H Koeppl, D Gonze PLoS computational biology 8 (3), e1002419, 2012 | 88 | 2012 |
| Cheminformatics tools for analyzing and designing optimized Small-Molecule collections and libraries N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ... Cell chemical biology 26 (5), 765-777. e3, 2019 | 72 | 2019 |
| RTK-dependent inducible degradation of mutant PI3Kα drives GDC-0077 (Inavolisib) efficacy KW Song, KA Edgar, EJ Hanan, M Hafner, J Oeh, M Merchant, D Sampath, ... Cancer discovery 12 (1), 204-219, 2022 | 64 | 2022 |
Peter K. SorgerHarvard Medical SchoolVerifierad e-postadress på hms.harvard.edu