Chrisostomos Prodromou

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Laurence PearlProfessor of Structural Biology, University of SussexVerifierad e-postadress på sussex.ac.uk
Mehdi MollapourSUNY Upstate Medical UniversityVerifierad e-postadress på upstate.edu
Giorgio ColomboUniversity of PaviaVerifierad e-postadress på unipv.it
Stephen KronUniversity of ChicagoVerifierad e-postadress på uchicago.edu
Donald J. WolfgeherUniversity of ChciagoVerifierad e-postadress på uchicago.edu
Rainer CramerProfessor of Mass Spectrometry and Bioanalytical SciencesVerifierad e-postadress på reading.ac.uk
Ken ShirasuRIKEN, Center for Sustainable Resource ScienceVerifierad e-postadress på riken.jp
Yasuhiro KadotaResearch Scientist, Riken Plant immunity research groupVerifierad e-postadress på riken.jp
William LewisSydney Analytical and School of Chemistry, University of SydneyVerifierad e-postadress på sydney.edu.au
Rahul S SamantBabraham InstituteVerifierad e-postadress på babraham.ac.uk
Carol V RobinsonProfessor of Chemistry University of OxfordVerifierad e-postadress på chem.ox.ac.uk
Brian DymockDirector of ChemistryVerifierad e-postadress på uniquest.com.au
Naushaba HasinLaboratory Research SupervisorVerifierad e-postadress på som.umaryland.edu
Kolbrun KristjansdottirAssociate Professor in Biomedical Sciences, Associate Director of Precision Medicine, College ofVerifierad e-postadress på midwestern.edu
Yoshihiko MiyataDepartment of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto UniversityVerifierad e-postadress på lif.kyoto-u.ac.jp
Robert MattsRegents and Sarkeys Distinguished Professor of Biochemistry and Molecular Biology, Oklahoma State UniversityVerifierad e-postadress på okstate.edu
Rachel AshworthQueen Mary University of LondonVerifierad e-postadress på qmul.ac.uk
Stephen W WilsonUCLVerifierad e-postadress på ucl.ac.uk
Anna-Pavlina HaramisInstitute of Biology, leiden UniversityVerifierad e-postadress på biology.leidenuniv.nl
Alexandra SlawinProfessor of Chemistry,University of St AndrewsVerifierad e-postadress på st-and.ac.uk

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Chrisostomos Prodromou

Senior Research Fellow, University of Sussex

Verifierad e-postadress på sussex.ac.uk

Chaperones Hsp90


Titel Sortera efter citat Sortera efter år Sortera efter titel	Citeras av Citeras av	År
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone C Prodromou, SM Roe, R O'Brien, JE Ladbury, PW Piper, LH Pearl Cell 90 (1), 65-75, 1997	1662	1997
Structure and mechanism of the Hsp90 molecular chaperone machinery LH Pearl, C Prodromou Annu. Rev. Biochem. 75 (1), 271-294, 2006	1398	2006
Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin SM Roe, C Prodromou, R O'Brien, JE Ladbury, PW Piper, LH Pearl Journal of medicinal chemistry 42 (2), 260-266, 1999	1256	1999
Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex MMU Ali, SM Roe, CK Vaughan, P Meyer, B Panaretou, PW Piper, ... Nature 440 (7087), 1013-1017, 2006	1179	2006
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo B Panaretou, C Prodromou, SM Roe, R O'Brien, JE Ladbury, PW Piper, ... The EMBO journal 17 (16), 4829-4836, 1998	944	1998
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1 B Panaretou, G Siligardi, P Meyer, A Maloney, JK Sullivan, S Singh, ... Molecular cell 10 (6), 1307-1318, 2002	664	2002
The ATPase cycle of Hsp90 drives a molecular ‘clamp’via transient dimerization of the N‐terminal domains C Prodromou, B Panaretou, S Chohan, G Siligardi, R O'Brien, JE Ladbury, ... The EMBO journal, 2000	653	2000
Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions P Meyer, C Prodromou, B Hu, C Vaughan, SM Roe, B Panaretou, ... Molecular cell 11 (3), 647-658, 2003	615	2003
Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)‐domain co‐chaperones C Prodromou, G Siligardi, R O'Brien, DN Woolfson, L Regan, B Panaretou, ... The EMBO journal, 1999	563	1999
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis SA Eccles, A Massey, FI Raynaud, SY Sharp, G Box, M Valenti, ... Cancer research 68 (8), 2850-2860, 2008	557	2008
The Hsp90 molecular chaperone: an open and shut case for treatment LH Pearl, C Prodromou, P Workman Biochemical Journal 410 (3), 439-453, 2008	552	2008
4, 5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer PA Brough, W Aherne, X Barril, J Borgognoni, K Boxall, JE Cansfield, ... Journal of medicinal chemistry 51 (2), 196-218, 2008	526	2008
Chaperoned ubiquitylation—crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex M Zhang, M Windheim, SM Roe, M Peggie, P Cohen, C Prodromou, ... Molecular cell 20 (4), 525-538, 2005	477	2005
Structure and in vivo function of Hsp90 LH Pearl, C Prodromou Current opinion in structural biology 10 (1), 46-51, 2000	449	2000
The mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50cdc37 SM Roe, MMU Ali, P Meyer, CK Vaughan, B Panaretou, PW Piper, ... Cell 116 (1), 87-98, 2004	432	2004
Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery P Meyer The EMBO journal 23 (6), 1402-1410, 2004	413	2004
Recursive PCR: a novel technique for total gene synthesis C Prodromou, LH Pearl Protein Engineering, Design and Selection 5 (8), 827-829, 1992	386	1992
Structure and functional relationships of Hsp90 C Prodromou, LH Pearl Current cancer drug targets 3 (5), 301-323, 2003	369	2003
Structure of an hsp90-cdc37-cdk4 complex CK Vaughan, U Gohlke, F Sobott, VM Good, MMU Ali, C Prodromou, ... Molecular cell 23 (5), 697-707, 2006	361	2006
Regulation of Hsp90 ATPase activity by the co-chaperone Cdc37p/p50cdc37 G Siligardi, B Panaretou, P Meyer, S Singh, DN Woolfson, PW Piper, ... Journal of biological chemistry 277 (23), 20151-20159, 2002	345	2002

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