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Basavarajappa D Halesha
Basavarajappa D Halesha
Scientist , Exelixis
Verifierad e-postadress på exelixis.com
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Natural product inhibitors of ocular angiogenesis
RS Sulaiman, HD Basavarajappa, TW Corson
Experimental eye research 129, 161-171, 2014
1012014
Aminopyrazinamides: Novel and Specific GyrB Inhibitors that Kill Replicating and Nonreplicating Mycobacterium tuberculosis
PS Shirude, P Madhavapeddi, JA Tucker, K Murugan, V Patil, ...
ACS chemical biology 8 (3), 519-523, 2013
952013
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA gyrase B
MG Kale, A Raichurkar, SH P, D Waterson, D McKinney, MR Manjunatha, ...
Journal of medicinal chemistry 56 (21), 8834-8848, 2013
702013
Synthesis and biological evaluation of novel homoisoflavonoids for retinal neovascularization
HD Basavarajappa, B Lee, H Lee, RS Sulaiman, H An, C Magaña, ...
Journal of Medicinal Chemistry 58 (12), 5015-5027, 2015
622015
The first synthesis of the antiangiogenic homoisoflavanone, cremastranone
B Lee, HD Basavarajappa, RS Sulaiman, X Fei, SY Seo, TW Corson
Organic & biomolecular chemistry 12 (39), 7673-7677, 2014
562014
Ferrochelatase is a therapeutic target for ocular neovascularization
HD Basavarajappa, RS Sulaiman, X Qi, T Shetty, S Sheik Pran Babu, ...
EMBO molecular medicine 9 (6), 786-801, 2017
512017
Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy
RR Kale, MG Kale, D Waterson, A Raichurkar, SP Hameed, ...
Bioorganic & Medicinal Chemistry Letters 24 (3), 870-879, 2014
462014
Transcriptional and epigenetic regulation of KIF14 overexpression in ovarian cancer
BL Thériault, HD Basavarajappa, H Lim, S Pajovic, BL Gallie, TW Corson
PLoS One 9 (3), e91540, 2014
452014
Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth
HD Basavarajappa, B Lee, X Fei, D Lim, B Callaghan, JA Mund, J Case, ...
PLoS One 9 (4), e95694, 2014
342014
The Antiangiogenic Activity of Naturally Occurring and Synthetic Homoisoflavonoids from the Hyacinthaceae (sensu APGII)
S Schwikkard, H Whitmore, K Sishtla, RS Sulaiman, T Shetty, ...
Journal of natural products 82 (5), 1227-1239, 2019
242019
Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids
B Lee, W Sun, H Lee, H Basavarajappa, RS Sulaiman, K Sishtla, X Fei, ...
Bioorganic & medicinal chemistry letters 26 (17), 4277-4281, 2016
242016
KIF14 As An Oncogene In Retinoblastoma: A Target For Novel Therapeutics?
HD Basavarajappa, TW Corson
Future medicinal chemistry 4 (17), 2149-2152, 2012
222012
Assays, surrogates, and alternative technologies for a TB lead identification program targeting DNA gyrase ATPase
V Humnabadkar, P Madhavapeddi, H Basavarajappa, MG Sheikh, ...
Journal of Biomolecular Screening 20 (2), 265-274, 2015
62015
The adaptor protein NumbL is involved in the control of glucolipotoxicity-induced pancreatic beta cell apoptosis
HD Basavarajappa, JM Irimia, BM Bauer, PT Fueger
International Journal of Molecular Sciences 24 (4), 3308, 2023
22023
Inhibition of ferrochelatase as an antiangiogenic therapy
T Corson, H Basavarajappa
US Patent 10,752,901, 2020
22020
Griseofulvin inhibits choroidal neovascularization
TW Corson, RS Sulaiman, S Alkhairy, K Gupta, HD Basavarajappa
Investigative Ophthalmology & Visual Science 57 (12), 2122-2122, 2016
22016
IDENTIFICATION AND CHARACTERIZATION OF A NOVEL SYNTHETIC HOMOISOFLAVONOID AS AN INHIBITOR OF RETINAL ANGIOGENESIS.
HD Basavarajappa, B Lee, J Quigley, R Sulaiman, G Rajashekhar, ...
Investigative ophthalmology & visual science 55 (13), 1266-1266, 2014
22014
Glucolipotoxic Stress-Induced Mig6 Desensitizes EGFR Signaling and Promotes Pancreatic Beta Cell Death
YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger
Metabolites 13 (5), 627, 2023
12023
Glucolipotoxicity-induced Mig6 desensitizes EGFR signaling and promotes pancreatic beta cell death
YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger
bioRxiv, 2020.11. 24.380279, 2020
12020
Compounds for treatment of angiogenesis-mediated diseases
TW Corson, HD Basavarajappa, SY Seo, B Lee, X Fei
US Patent 10,738,024, 2020
12020
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Artiklar 1–20