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Alexander Bick, MD PhD
Alexander Bick, MD PhD
Director, Division of Genetic Medicine, Vanderbilt
Verifierad e-postadress på vumc.org - Startsida
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Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease
S Jaiswal, P Natarajan, AJ Silver, CJ Gibson, AG Bick, E Shvartz, ...
New England Journal of Medicine 377 (2), 111-121, 2017
23632017
Genetic risk, adherence to a healthy lifestyle, and coronary disease
AV Khera, CA Emdin, I Drake, P Natarajan, AG Bick, NR Cook, ...
New England Journal of Medicine 375 (24), 2349-2358, 2016
14832016
Diagnostic yield and clinical utility of sequencing familial hypercholesterolemia genes in patients with severe hypercholesterolemia
AV Khera, HH Won, GM Peloso, KS Lawson, TM Bartz, X Deng, ...
Journal of the American College of Cardiology 67 (22), 2578-2589, 2016
9692016
Polygenic prediction of weight and obesity trajectories from birth to adulthood
AV Khera, M Chaffin, KH Wade, S Zahid, J Brancale, R Xia, M Distefano, ...
Cell 177 (3), 587-596. e9, 2019
7522019
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ...
Nature 586 (7831), 763-768, 2020
5992020
Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease
AM Roberts, JS Ware, DS Herman, S Schafer, J Baksi, AG Bick, ...
Science translational medicine 7 (270), 270ra6-270ra6, 2015
5082015
Single-Cell Resolution of Temporal Gene Expression during Heart Development
DM DeLaughter, AG Bick, H Wakimoto, D McKean, JM Gorham, ...
Developmental Cell 39 (4), 480-490, 2016
4422016
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
AC Fahed, M Wang, JR Homburger, AP Patel, AG Bick, CL Neben, C Lai, ...
Nature communications 11 (1), 3635, 2020
4102020
Genetic interleukin 6 signaling deficiency attenuates cardiovascular risk in clonal hematopoiesis
AG Bick, JP Pirruccello, GK Griffin, N Gupta, S Gabriel, D Saleheen, ...
Circulation 141 (2), 124-131, 2020
3572020
Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data
JT Glessner, AG Bick, K Ito, JG Homsy, L Rodriguez-Murillo, M Fromer, ...
Circulation research 115 (10), 884-896, 2014
2852014
Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans
RP Naik, VK Derebail, ME Grams, N Franceschini, PL Auer, GM Peloso, ...
JAMA 312 (20), 2115-2125, 2014
2402014
Mechanically robust and bioadhesive collagen and photocrosslinkable hyaluronic acid semi-interpenetrating networks
MD Brigham, A Bick, E Lo, A Bendali, JA Burdick, A Khademhosseini
Tissue Engineering Part A 15 (7), 1645-1653, 2009
2382009
Phenotypic Characterization of Genetically Lowered Human Lipoprotein (a) Levels
CA Emdin, AV Khera, P Natarajan, D Klarin, HH Won, GM Peloso, ...
Journal of the American College of Cardiology 68 (25), 2761-2772, 2016
2312016
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
C Tcheandjieu, X Zhu, AT Hilliard, SL Clarke, V Napolioni, S Ma, KM Lee, ...
Nature medicine 28 (8), 1679-1692, 2022
2192022
Genomic data in the All of Us Research Program
AG Bick, GA Metcalf, KR Mayo, L Lichtenstein, S Rura, RJ Carroll, ...
Nature, 2024
216*2024
Distinction of lymphoid and myeloid clonal hematopoiesis
A Niroula, A Sekar, MA Murakami, M Trinder, M Agrawal, WJ Wong, ...
Nature Medicine 27 (11), 1921-1927, 2021
2102021
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy
JP Pirruccello, A Bick, M Wang, M Chaffin, S Friedman, J Yao, X Guo, ...
Nature communications 11 (1), 2254, 2020
2102020
Prediction of risk for myeloid malignancy in clonal hematopoiesis
LD Weeks, A Niroula, D Neuberg, W Wong, RC Lindsley, MR Luskin, ...
NEJM Evidence 2 (5), EVIDoa2200310, 2023
1862023
Controllable Microfluidic Production of Microbubbles in Water‐in‐Oil Emulsions and the Formation of Porous Microparticles
J Wan, A Bick, M Sullivan, HA Stone
Advanced Materials 20 (17), 3314-3318, 2008
1812008
Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease
CS Marnell, A Bick, P Natarajan
Journal of Molecular and Cellular Cardiology 161, 98-105, 2021
1792021
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