| Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab HS Cho, K Mason, KX Ramyar, AM Stanley, SB Gabelli, DW Denney Jr, ... Nature 421 (6924), 756-760, 2003 | 2063 | 2003 |
| The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations CH Huang, D Mandelker, O Schmidt-Kittler, Y Samuels, VE Velculescu, ... Science 318 (5857), 1744-1748, 2007 | 674 | 2007 |
| Salting out of proteins using ammonium sulfate precipitation KC Duong-Ly, SB Gabelli Methods in enzymology 541, 85-94, 2014 | 424 | 2014 |
| Structures and mechanisms of Nudix hydrolases AS Mildvan, Z Xia, HF Azurmendi, V Saraswat, PM Legler, MA Massiah, ... Archives of biochemistry and biophysics 433 (1), 129-143, 2005 | 354 | 2005 |
| A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane D Mandelker, SB Gabelli, O Schmidt-Kittler, J Zhu, I Cheong, CH Huang, ... Proceedings of the National Academy of Sciences 106 (40), 16996-17001, 2009 | 325 | 2009 |
| Targeting a neoantigen derived from a common TP53 mutation EHC Hsiue, KM Wright, J Douglass, MS Hwang, BJ Mog, AH Pearlman, ... Science 371 (6533), eabc8697, 2021 | 290 | 2021 |
| Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid SAJ Messing, SB Gabelli, I Echeverria, JT Vogel, JC Guan, BC Tan, ... The Plant Cell 22 (9), 2970-2980, 2010 | 209 | 2010 |
| Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design SB Gabelli, JS McLellan, A Montalvetti, E Oldfield, R Docampo, LM Amzel Proteins: Structure, Function, and Bioinformatics 62 (1), 80-88, 2006 | 180 | 2006 |
| Rapid PD-L1 detection in tumors with PET using a highly specific peptide S Chatterjee, WG Lesniak, MS Miller, A Lisok, E Sikorska, B Wharram, ... Biochemical and biophysical research communications 483 (1), 258-263, 2017 | 177 | 2017 |
| The structure of ADP-ribose pyrophosphatase reveals the structural basis for the versatility of the Nudix family SB Gabelli, MA Bianchet, MJ Bessman, LM Amzel Nature structural biology 8 (5), 467-472, 2001 | 152 | 2001 |
| Bispecific antibodies targeting mutant RAS neoantigens J Douglass, EHC Hsiue, BJ Mog, MS Hwang, SR DiNapoli, AH Pearlman, ... Science immunology 6 (57), eabd5515, 2021 | 140 | 2021 |
| Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions H Nakamura, AA Lee, AS Afshar, S Watanabe, E Rho, S Razavi, A Suarez, ... Nature materials 17 (1), 79-89, 2018 | 133 | 2018 |
| Targeting public neoantigens for cancer immunotherapy AH Pearlman, MS Hwang, MF Konig, EHC Hsiue, J Douglass, ... Nature cancer 2 (5), 487-497, 2021 | 132 | 2021 |
| Akt kinase activation mechanisms revealed using protein semisynthesis N Chu, AL Salguero, AZ Liu, Z Chen, DR Dempsey, SB Ficarro, ... Cell 174 (4), 897-907. e14, 2018 | 130 | 2018 |
| C-terminal recognition by 14-3-3 proteins for surface expression of membrane receptors B Coblitz, S Shikano, M Wu, SB Gabelli, LM Cockrell, M Spieker, Y Hanyu, ... Journal of Biological Chemistry 280 (43), 36263-36272, 2005 | 122 | 2005 |
| Structural comparisons of class I phosphoinositide 3-kinases LM Amzel, CH Huang, D Mandelker, C Lengauer, SB Gabelli, ... Nature Reviews Cancer 8 (9), 665-669, 2008 | 121 | 2008 |
| Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis D Bolduc, M Rahdar, B Tu-Sekine, SC Sivakumaren, D Raben, LM Amzel, ... Elife 2, e00691, 2013 | 120 | 2013 |
| Insights into the oncogenic effects of/PIK3CA/mutations from the structure of p110α/p85α CH Huang, D Mandelker, SB Gabelli, LM Amzel Cell cycle 7 (9), 1151-1156, 2008 | 107 | 2008 |
| A tunable brake for HECT ubiquitin ligases Z Chen, H Jiang, W Xu, X Li, DR Dempsey, X Zhang, P Devreotes, ... Molecular cell 66 (3), 345-357. e6, 2017 | 106 | 2017 |
| A redox regulatory system critical for mycobacterial survival in macrophages and biofilm development KA Wolff, AH de la Peña, HT Nguyen, TH Pham, LM Amzel, SB Gabelli, ... PLoS pathogens 11 (4), e1004839, 2015 | 105 | 2015 |