Naive CD4+ T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude JJ Moon, HH Chu, M Pepper, SJ McSorley, SC Jameson, RM Kedl, ... Immunity 27 (2), 203-213, 2007 | 1156 | 2007 |
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire MA Burchill, J Yang, KB Vang, JJ Moon, HH Chu, CWJ Lio, AL Vegoe, ... Immunity 28 (1), 112-121, 2008 | 523 | 2008 |
Tracking epitope-specific T cells JJ Moon, HH Chu, J Hataye, AJ Pagán, M Pepper, JB McLachlan, T Zell, ... Nature protocols 4 (4), 565-581, 2009 | 350 | 2009 |
On the composition of the preimmune repertoire of T cells specific for peptide–major histocompatibility complex ligands MK Jenkins, HH Chu, JB McLachlan, JJ Moon Annual review of immunology 28 (1), 275-294, 2010 | 306 | 2010 |
Quantitative impact of thymic selection on Foxp3+ and Foxp3− subsets of self-peptide/MHC class II-specific CD4+ T cells JJ Moon, P Dash, TH Oguin III, JL McClaren, HH Chu, PG Thomas, ... Proceedings of the National Academy of Sciences 108 (35), 14602-14607, 2011 | 132 | 2011 |
Local changes in lipid environment of TCR microclusters regulate membrane binding by the CD3ε cytoplasmic domain E Gagnon, DA Schubert, S Gordo, HH Chu, KW Wucherpfennig The Journal of experimental medicine 209 (13), 2423, 2012 | 118 | 2012 |
Continuous effector CD8+ T cell production in a controlled persistent infection is sustained by a proliferative intermediate population HH Chu, SW Chan, JP Gosling, N Blanchard, A Tsitsiklis, G Lythe, ... Immunity 45 (1), 159-171, 2016 | 88 | 2016 |
Location of the CD8 T Cell Epitope within the Antigenic Precursor Determines Immunogenicity and Protection against the Toxoplasma gondii Parasite V Feliu, V Vasseur, HS Grover, HH Chu, MJ Brown, J Wang, JP Boyle, ... PLoS pathogens 9 (6), e1003449, 2013 | 70 | 2013 |
Dendritic cells amplify T cell-mediated immune responses in the central nervous system J Karman, HH Chu, DO Co, CM Seroogy, M Sandor, Z Fabry The Journal of Immunology 177 (11), 7750-7760, 2006 | 58 | 2006 |
Negative selection and peptide chemistry determine the size of naive foreign peptide–MHC class II-specific CD4+ T cell populations HH Chu, JJ Moon, AC Kruse, M Pepper, MK Jenkins The Journal of immunology 185 (8), 4705-4713, 2010 | 54 | 2010 |
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire HH Chu, JJ Moon, K Takada, M Pepper, JA Molitor, TW Schacker, ... Proceedings of the National Academy of Sciences 106 (27), 11241-11245, 2009 | 53 | 2009 |
The transcription factors Thpok and LRF are necessary and partly redundant for T helper cell differentiation AC Carpenter, JR Grainger, Y Xiong, Y Kanno, HH Chu, L Wang, S Naik, ... Immunity 37 (4), 622-633, 2012 | 45 | 2012 |
CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs AJ Pagán, M Pepper, HH Chu, JM Green, MK Jenkins The Journal of immunology 189 (6), 2909-2917, 2012 | 44 | 2012 |
Response multilayered control of T cell receptor phosphorylation E Gagnon, C Xu, W Yang, HH Chu, ME Call, JJ Chou, KW Wucherpfennig Cell 142 (5), 669-671, 2010 | 41 | 2010 |
TCR ITAM multiplicity is required for the generation of follicular helper T-cells SJ Hwang, AC Palin, LQ Li, KD Song, J Lee, J Herz, N Tubo, H Chu, ... Nature communications 6 (1), 6982, 2015 | 40 | 2015 |
Impact of regulated secretion on antiparasitic CD8 T cell responses HS Grover, HH Chu, FD Kelly, SJ Yang, ML Reese, N Blanchard, ... Cell reports 7 (5), 1716-1728, 2014 | 33 | 2014 |
Naive CD4 (+) T cell frequency varies for different application to human mitochondrial DNA restriction data JJ Moon, HH Chu, M Pepper, SJ McSorley, SC Jameson, RM Kedl, ... Genetics 131, 479-491, 2007 | 22 | 2007 |
The same well-characterized T cell epitope SIINFEKL expressed in the context of a cytoplasmic or secreted protein in BCG induces different CD8+ T cell responses PD Hulseberg, A Zozulya, HH Chu, JA Triccas, Z Fabry, M Sandor Immunology letters 130 (1-2), 36-42, 2010 | 16 | 2010 |
847 Pharmacokinetics and pharmacodynamics of GS-3583 in cynomolgus monkeys M Kuhne, H Chu, C Clarke, B Carr, M Baca, M Hung, M Nagel, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A888-A888, 2021 | 1 | 2021 |
846 Pre-clinical validation of a FLT3L-fusion protein for dendritic cell expansion and anti-tumor efficacy M Kuhne, H Chu, S Ng, C Clarke, B Carr, M Baca, M Hung, M Nagel, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A887-A887, 2021 | 1 | 2021 |