PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation T Varga, Z Czimmerer, L Nagy Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (8 …, 2011 | 1024 | 2011 |
The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages Z Czimmerer, B Daniel, A Horvath, D Rückerl, G Nagy, M Kiss, M Peloquin, ... Immunity 48 (1), 75-90. e6, 2018 | 239 | 2018 |
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery J Oberoi, L Fairall, PJ Watson, JC Yang, Z Czimmerer, T Kampmann, ... Nature structural & molecular biology 18 (2), 177-184, 2011 | 203 | 2011 |
The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology M Kiss, Z Czimmerer, L Nagy Journal of Allergy and Clinical Immunology 132 (2), 264-286, 2013 | 180 | 2013 |
miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5 E Miko, Z Margitai, Z Czimmerer, I Várkonyi, B Dezső, Á Lányi, Z Bacsó, ... FEBS letters 585 (8), 1191-1196, 2011 | 161 | 2011 |
The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory B Daniel, G Nagy, Z Czimmerer, A Horvath, DW Hammers, ... Immunity 49 (4), 615-626. e6, 2018 | 160 | 2018 |
Differentially expressed microRNAs in small cell lung cancer E Miko, Z Czimmerer, E Csánky, G Boros, J Buslig, B Dezső, B Scholtz Experimental lung research 35 (8), 646-664, 2009 | 151 | 2009 |
A versatile method to design stem-loop primer-based quantitative PCR assays for detecting small regulatory RNA molecules Z Czimmerer, J Hulvely, Z Simandi, E Varallyay, Z Havelda, E Szabo, ... PloS one 8 (1), e55168, 2013 | 141 | 2013 |
The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages B Daniel, G Nagy, N Hah, A Horvath, Z Czimmerer, S Poliska, T Gyuris, ... Genes & development 28 (14), 1562-1577, 2014 | 106 | 2014 |
Hyperglycaemia suppresses microRNA expression in platelets to increase P2RY12 and SELP levels in type 2 diabetes mellitus Z Fejes, S Póliska, Z Czimmerer, M Káplár, A Penyige, GG Szabó, ... Thrombosis and Haemostasis 117 (03), 529-542, 2017 | 96 | 2017 |
Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages Z Czimmerer, T Varga, S Poliska, I Nemet, A Szanto, L Nagy Immunobiology 217 (12), 1301-1314, 2012 | 64 | 2012 |
The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages B Daniel, G Nagy, A Horvath, Z Czimmerer, I Cuaranta-Monroy, S Poliska, ... Nucleic acids research 46 (9), 4425-4439, 2018 | 62 | 2018 |
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization B Daniel, Z Czimmerer, L Halasz, P Boto, Z Kolostyak, S Poliska, ... Genes & development 34 (21-22), 1474-1492, 2020 | 47 | 2020 |
The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p Z Czimmerer, T Varga, M Kiss, CO Vázquez, QM Doan-Xuan, D Rückerl, ... Genome medicine 8, 1-22, 2016 | 47 | 2016 |
Pro-inflammatory cytokines negatively regulate PPARγ mediated gene expression in both human and murine macrophages via multiple mechanisms ZS Nagy, Z Czimmerer, A Szanto, L Nagy Immunobiology 218 (11), 1336-1344, 2013 | 46 | 2013 |
Liver X receptor nuclear receptors are transcriptional regulators of dendritic cell chemotaxis S Beceiro, A Pap, Z Czimmerer, T Sallam, JA Guillén, G Gallardo, C Hong, ... Molecular and cellular biology 38 (10), e00534-17, 2018 | 45 | 2018 |
Reduced miR-26b expression in megakaryocytes and platelets contributes to elevated level of platelet activation status in sepsis B Szilágyi, Z Fejes, S Póliska, M Pócsi, Z Czimmerer, A Patsalos, ... International Journal of Molecular Sciences 21 (3), 866, 2020 | 43 | 2020 |
The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands Z Czimmerer, L Halasz, B Daniel, Z Varga, K Bene, A Domokos, ... Immunity 55 (11), 2006-2026. e6, 2022 | 38 | 2022 |
Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism ZS Nagy, Z Czimmerer, L Nagy Molecular and cellular endocrinology 368 (1-2), 85-98, 2013 | 29 | 2013 |
Embryonic exposure to low concentrations of aflatoxin B1 triggers global transcriptomic changes, defective yolk lipid mobilization, abnormal gastrointestinal tract development … B Ivanovics, G Gazsi, M Reining, I Berta, S Poliska, M Toth, A Domokos, ... Journal of Hazardous Materials 416, 125788, 2021 | 28 | 2021 |