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Zsolt Czimmerer
Zsolt Czimmerer
Verifierad e-postadress på brc.hu
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PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
T Varga, Z Czimmerer, L Nagy
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (8 …, 2011
10242011
The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages
Z Czimmerer, B Daniel, A Horvath, D Rückerl, G Nagy, M Kiss, M Peloquin, ...
Immunity 48 (1), 75-90. e6, 2018
2392018
Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery
J Oberoi, L Fairall, PJ Watson, JC Yang, Z Czimmerer, T Kampmann, ...
Nature structural & molecular biology 18 (2), 177-184, 2011
2032011
The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology
M Kiss, Z Czimmerer, L Nagy
Journal of Allergy and Clinical Immunology 132 (2), 264-286, 2013
1802013
miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5
E Miko, Z Margitai, Z Czimmerer, I Várkonyi, B Dezső, Á Lányi, Z Bacsó, ...
FEBS letters 585 (8), 1191-1196, 2011
1612011
The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory
B Daniel, G Nagy, Z Czimmerer, A Horvath, DW Hammers, ...
Immunity 49 (4), 615-626. e6, 2018
1602018
Differentially expressed microRNAs in small cell lung cancer
E Miko, Z Czimmerer, E Csánky, G Boros, J Buslig, B Dezső, B Scholtz
Experimental lung research 35 (8), 646-664, 2009
1512009
A versatile method to design stem-loop primer-based quantitative PCR assays for detecting small regulatory RNA molecules
Z Czimmerer, J Hulvely, Z Simandi, E Varallyay, Z Havelda, E Szabo, ...
PloS one 8 (1), e55168, 2013
1412013
The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages
B Daniel, G Nagy, N Hah, A Horvath, Z Czimmerer, S Poliska, T Gyuris, ...
Genes & development 28 (14), 1562-1577, 2014
1062014
Hyperglycaemia suppresses microRNA expression in platelets to increase P2RY12 and SELP levels in type 2 diabetes mellitus
Z Fejes, S Póliska, Z Czimmerer, M Káplár, A Penyige, GG Szabó, ...
Thrombosis and Haemostasis 117 (03), 529-542, 2017
962017
Identification of novel markers of alternative activation and potential endogenous PPARγ ligand production mechanisms in human IL-4 stimulated differentiating macrophages
Z Czimmerer, T Varga, S Poliska, I Nemet, A Szanto, L Nagy
Immunobiology 217 (12), 1301-1314, 2012
642012
The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages
B Daniel, G Nagy, A Horvath, Z Czimmerer, I Cuaranta-Monroy, S Poliska, ...
Nucleic acids research 46 (9), 4425-4439, 2018
622018
The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization
B Daniel, Z Czimmerer, L Halasz, P Boto, Z Kolostyak, S Poliska, ...
Genes & development 34 (21-22), 1474-1492, 2020
472020
The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p
Z Czimmerer, T Varga, M Kiss, CO Vázquez, QM Doan-Xuan, D Rückerl, ...
Genome medicine 8, 1-22, 2016
472016
Pro-inflammatory cytokines negatively regulate PPARγ mediated gene expression in both human and murine macrophages via multiple mechanisms
ZS Nagy, Z Czimmerer, A Szanto, L Nagy
Immunobiology 218 (11), 1336-1344, 2013
462013
Liver X receptor nuclear receptors are transcriptional regulators of dendritic cell chemotaxis
S Beceiro, A Pap, Z Czimmerer, T Sallam, JA Guillén, G Gallardo, C Hong, ...
Molecular and cellular biology 38 (10), e00534-17, 2018
452018
Reduced miR-26b expression in megakaryocytes and platelets contributes to elevated level of platelet activation status in sepsis
B Szilágyi, Z Fejes, S Póliska, M Pócsi, Z Czimmerer, A Patsalos, ...
International Journal of Molecular Sciences 21 (3), 866, 2020
432020
The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands
Z Czimmerer, L Halasz, B Daniel, Z Varga, K Bene, A Domokos, ...
Immunity 55 (11), 2006-2026. e6, 2022
382022
Nuclear receptor mediated mechanisms of macrophage cholesterol metabolism
ZS Nagy, Z Czimmerer, L Nagy
Molecular and cellular endocrinology 368 (1-2), 85-98, 2013
292013
Embryonic exposure to low concentrations of aflatoxin B1 triggers global transcriptomic changes, defective yolk lipid mobilization, abnormal gastrointestinal tract development …
B Ivanovics, G Gazsi, M Reining, I Berta, S Poliska, M Toth, A Domokos, ...
Journal of Hazardous Materials 416, 125788, 2021
282021
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Artiklar 1–20