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Galen Wright
Galen Wright
Canada Research Chair in Neurogenomics. Assistant Professor, University of Manitoba
Verifierad e-postadress på umanitoba.ca - Startsida
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Huntington disease
NS Caron, GEB Wright, MR Hayden
GeneReviews®[Internet], 2020
221*2020
Length of uninterrupted CAG, independent of polyglutamine size, results in increased somatic instability, hastening onset of Huntington disease
GEB Wright, JA Collins, C Kay, C McDonald, E Dolzhenko, Q Xia, ...
The American Journal of Human Genetics 104 (6), 1116-1126, 2019
1972019
Nuclear receptor NR1H3 in familial multiple sclerosis
Z Wang, AD Sadovnick, AL Traboulsee, JP Ross, CQ Bernales, ...
Neuron 90 (5), 948-954, 2016
1242016
Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in GLS
ABP van Kuilenburg, M Tarailo-Graovac, PA Richmond, BI Drögemöller, ...
New England Journal of Medicine 380 (15), 1433-1441, 2019
962019
Pharmacogenomic research in South Africa: lessons learned and future opportunities in the rainbow nation
L Warnich, B I Drogemoller, M S Pepper, C Dandara, G EB Wright
Current Pharmacogenomics and Personalized Medicine 9 (3), 191-207, 2011
922011
The global spectrum of protein-coding pharmacogenomic diversity
GEB Wright, B Carleton, MR Hayden, CJD Ross
The Pharmacogenomics Journal 18, 187–195, 2018
842018
Ethical and legal implications of whole genome and whole exome sequencing in African populations
GEB Wright, PGJ Koornhof, AA Adeyemo, N Tiffin
BMC Medical Ethics 14 (1), 21, 2013
802013
The molecular epidemiology of Huntington disease is related to intermediate allele frequency and haplotype in the general population
C Kay, JA Collins, GEB Wright, F Baine, Z Miedzybrodzka, F Aminkeng, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177 …, 2018
792018
Pharmacogenomics of vincristine‐induced peripheral neuropathy implicates pharmacokinetic and inherited neuropathy genes
GEB Wright, U Amstutz, BI Drögemöller, J Shih, SR Rassekh, MR Hayden, ...
Clinical Pharmacology & Therapeutics 105 (2), 402-410, 2019
742019
Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies
GEB Wright, HF Black, JA Collins, T Gall-Duncan, NS Caron, CE Pearson, ...
The Lancet Neurology 19 (11), 930-939, 2020
672020
SJS/TEN 2019: from science to translation
WC Chang, R Abe, P Anderson, W Anderson, MR Ardern-Jones, ...
Journal of dermatological science 98 (1), 2-12, 2020
662020
Characterization of the Genetic Profile of CYP2C19 in Two South African Populations
BI Drögemöller, GEB Wright, DJH Niehaus, L Koen, S Malan, DM Da Silva, ...
Pharmacogenomics 11 (8), 1095-1103, 2010
662010
Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population
GEB Wright, DJH Niehaus, BI Drögemöller, L Koen, A Gaedigk, L Warnich
Annals of Human Genetics 74 (4), 340-350, 2010
662010
Association between SLC16A5 genetic variation and cisplatin-induced ototoxic effects in adult patients with testicular cancer
BI Drögemöller, JG Monzon, AP Bhavsar, AE Borrie, B Brooks, ...
JAMA Oncology 3 (11), 1558-1562, 2017
622017
Characterization of the genetic variation present in CYP3A4 in three South African populations
BI Drögemöller, M Plummer, L Korkie, G Agenbag, A Dunaiski, D Niehaus, ...
Frontiers in Genetics 4, 17, 2013
552013
Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study
TM Dodgen, WE Hochfeld, H Fickl, SM Asfaha, C Durandt, P Rheeder, ...
BMC Medical Genetics 14 (1), 20, 2013
542013
A systematic comparison of pharmacogene star allele calling bioinformatics algorithms: a focus on CYP2D6 genotyping
D Twesigomwe, GEB Wright, BI Drögemöller, J Da Rocha, Z Lombard, ...
NPJ genomic medicine 5 (1), 30, 2020
522020
Further Investigation of the Role of ACYP2 and WFS1 Pharmacogenomic Variants in the Development of Cisplatin-Induced Ototoxicity in Testicular Cancer Patients
BI Drögemöller, B Brooks, C Critchley, JG Monzon, GEB Wright, G Liu, ...
Clinical Cancer Research 24 (8), 1866-1871, 2018
502018
Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients
M McCormack, H Gui, A Ingason, D Speed, GEB Wright, EJ Zhang, ...
Neurology 90 (4), e332-e341, 2018
492018
Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range
H Findlay Black, GEB Wright, JA Collins, N Caron, C Kay, Q Xia, L Arning, ...
Genetics in Medicine 22 (12), 2108-2113, 2020
482020
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