PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability A Silva, JA Yunes, BA Cardoso, LR Martins, PY Jotta, M Abecasis, ... The Journal of clinical investigation 118 (11), 3762-3774, 2008 | 503 | 2008 |
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia PP Zenatti, D Ribeiro, W Li, L Zuurbier, MC Silva, M Paganin, J Tritapoe, ... Nature genetics 43 (10), 932-939, 2011 | 499 | 2011 |
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma JA Perry, A Kiezun, P Tonzi, EM Van Allen, SL Carter, SC Baca, ... Proceedings of the National Academy of Sciences 111 (51), E5564-E5573, 2014 | 460 | 2014 |
The potential role of systemic buffers in reducing intratumoral extracellular pH and acid-mediated invasion AS Silva, JA Yunes, RJ Gillies, RA Gatenby Cancer research 69 (6), 2677-2684, 2009 | 244 | 2009 |
Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia DA Moreno, CA Scrideli, MAA Cortez, R de Paula Queiroz, ET Valera, ... British journal of haematology 150 (6), 665-673, 2010 | 236 | 2010 |
IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias A Silva, ABA Laranjeira, LR Martins, BA Cardoso, J Demengeot, ... Cancer research 71 (14), 4780-4789, 2011 | 164 | 2011 |
Transcriptome analysis of the oil-rich seed of the bioenergy crop Jatropha curcas L GGL Costa, KC Cardoso, LEV Del Bem, AC Lima, MAS Cunha, ... BMC genomics 11, 1-9, 2010 | 160 | 2010 |
Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia PY Jotta, MA Ganazza, A Silva, MB Viana, MJ Da Silva, LJG Zambaldi, ... Leukemia 24 (1), 239-242, 2010 | 113 | 2010 |
Differential miRNA expression in childhood acute lymphoblastic leukemia and association with clinical and biological features JC de Oliveira, CA Scrideli, MS Brassesco, AG Morales, JA Pezuk, ... Leukemia Research 36 (3), 293-298, 2012 | 111 | 2012 |
Benefits of the intermittent use of 6-mercaptopurine and methotrexate in maintenance treatment for low-risk acute lymphoblastic leukemia in children: randomized trial from the … SR Brandalise, VR Pinheiro, SS Aguiar, EI Matsuda, R Otubo, JA Yunes, ... Journal of Clinical Oncology 28 (11), 1911-1918, 2010 | 110 | 2010 |
The involvement of Opaque 2 on β-prolamin gene regulation in maize and Coix suggests a more general role for this transcriptional activator GC Neto, JA Yunes, MJ da Silva, AL Vettore, P Arruda, A Leite Plant molecular biology 27, 1015-1029, 1995 | 101 | 1995 |
PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events RD Mendes, LM Sarmento, K Canté-Barrett, L Zuurbier, ... Blood, The Journal of the American Society of Hematology 124 (4), 567-578, 2014 | 95 | 2014 |
Prospective evaluation of HSV, Candida spp., and oral bacteria on the severity of oral mucositis in pediatric acute lymphoblastic leukemia RMH de Mendonça, M de Araújo, CE Levy, J Morari, RA Silva, JA Yunes, ... Supportive Care in Cancer 20, 1101-1107, 2012 | 90 | 2012 |
Cytotoxic 3, 4, 5-trimethoxychalcones as mitotic arresters and cell migration inhibitors LB Salum, WF Altei, LD Chiaradia, MNS Cordeiro, RR Canevarolo, ... European journal of medicinal chemistry 63, 501-510, 2013 | 88 | 2013 |
Increased CCL2 and IL‐8 in the bone marrow microenvironment in acute lymphoblastic leukemia JF de Vasconcellos, ABA Laranjeira, NIT Zanchin, R Otubo, TH Vaz, ... Pediatric blood & cancer 56 (4), 568-577, 2011 | 85 | 2011 |
Association of the germline TP53R337H mutation with breast cancer in southern Brazil JG Assumpção, AL Seidinger, MJ Mastellaro, RC Ribeiro, GP Zambetti, ... BMC cancer 8, 1-6, 2008 | 85 | 2008 |
Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340) RP Siqueira, ÉAA Barbosa, MD Polêto, GL Righetto, TV Seraphim, ... PloS one 10 (8), e0134882, 2015 | 82 | 2015 |
Association of the highly prevalent TP53 R337H mutation with pediatric choroid plexus carcinoma and osteosarcoma in Southeast Brazil AL Seidinger, MJ Mastellaro, F Paschoal Fortes, J Godoy Assumpção, ... Cancer 117 (10), 2228-2235, 2011 | 81 | 2011 |
Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2-and γ-secretase inhibitors A Silva, PY Jotta, AB Silveira, D Ribeiro, SR Brandalise, JA Yunes, ... Haematologica 95 (4), 674, 2009 | 81 | 2009 |
The transcriptional activator Opaque2 recognizes two different target sequences in the 22-kD-like alpha-prolamin genes. JA Yunes, G Cord Neto, MJ da Silva, A Leite, LM Ottoboni, P Arruda The Plant Cell 6 (2), 237-249, 1994 | 81 | 1994 |