Enhanced utilization of induced pluripotent stem cell-derived human intestinal organoids using microengineered Chips MJ Workman, JP Gleeson, EJ Troisi, HQ Estrada, SJ Kerns, CD Hinojosa, ... Cellular and Molecular Gastroenterology and Hepatology, 2017 | 237 | 2017 |
Safety concerns over the use of intestinal permeation enhancers: A mini-review F McCartney, JP Gleeson, DJ Brayden Tissue barriers 4 (2), e1176822, 2016 | 146 | 2016 |
Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers JP Gleeson, SM Ryan, DJ Brayden Trends in Food Science & Technology 53, 90-101, 2016 | 130 | 2016 |
A head-to-head multi-parametric high content analysis of a series of medium chain fatty acid intestinal permeation enhancers in Caco-2 cells DJ Brayden, J Gleeson, EG Walsh European journal of pharmaceutics and biopharmaceutics 88 (3), 830-839, 2014 | 89 | 2014 |
Evaluation of PepT1 transport of food-derived antihypertensive peptides, Ile-Pro-Pro and Leu-Lys-Pro using in vitro, ex vivo and in vivo transport models JP Gleeson, DJ Brayden, SM Ryan European Journal of Pharmaceutics and Biopharmaceutics 115, 276-284, 2017 | 59 | 2017 |
Stability, toxicity and intestinal permeation enhancement of two food-derived antihypertensive tripeptides, Ile-Pro-Pro and Leu-Lys-Pro JP Gleeson, J Heade, SM Ryan, DJ Brayden Peptides 71, 1-7, 2015 | 49 | 2015 |
Excess growth hormone suppresses DNA damage repair in epithelial cells V Chesnokova, S Zonis, R Barrett, H Kameda, K Wawrowsky, ... JCI insight 4 (3), e125762, 2019 | 44 | 2019 |
The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology JP Gleeson, KC Fein, N Chaudhary, R Doerfler, AN Newby, ... International journal of pharmaceutics 593, 120120, 2021 | 33 | 2021 |
Sodium caprate enables the blood pressure-lowering effect of Ile-Pro-Pro and Leu-Lys-Pro in spontaneously hypertensive rats by indirectly overcoming PepT1 inhibition JP Gleeson, JM Frías, SM Ryan, DJ Brayden European Journal of Pharmaceutics and Biopharmaceutics 128, 179-187, 2018 | 33 | 2018 |
Oral delivery of peptide therapeutics in infants: Challenges and opportunities JP Gleeson, KC Fein, KA Whitehead Advanced drug delivery reviews 173, 112, 2021 | 32 | 2021 |
Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations JP Gleeson, N Chaudhary, KC Fein, R Doerfler, P Hredzak-Showalter, ... Science Advances 8 (26), eabm6865, 2022 | 30 | 2022 |
Development of physiologically responsive human iPSC-derived intestinal epithelium to study barrier dysfunction in IBD JP Gleeson, HQ Estrada, M Yamashita, CN Svendsen, SR Targan, ... International Journal of Molecular Sciences 21 (4), 1438, 2020 | 29 | 2020 |
Growth hormone induces colon DNA damage independent of IGF-1 V Chesnokova, S Zonis, RJ Barrett, JP Gleeson, S Melmed Endocrinology 160 (6), 1439-1447, 2019 | 27 | 2019 |
Diet, food components and the intestinal barrier JP Gleeson Nutrition Bulletin 42 (2), 123-131, 2017 | 26 | 2017 |
Intestinal permeation enhancers enable oral delivery of macromolecules up to 70 kDa in size KC Fein, JP Gleeson, AN Newby, KA Whitehead European Journal of Pharmaceutics and Biopharmaceutics 170, 70-76, 2022 | 24 | 2022 |
Striving towards the perfect in vitro oral drug absorption model JP Gleeson, F McCartney Trends in pharmacological sciences 40 (10), 720-724, 2019 | 24 | 2019 |
Formulation, characterisation and evaluation of the antihypertensive peptides, isoleucine-proline-proline and leucine-lysine-proline in chitosan nanoparticles coated with zein … M Khalid Danish, JP Gleeson, DJ Brayden, HJ Byrne, JM Frías, SM Ryan International journal of molecular sciences 23 (19), 11160, 2022 | 19 | 2022 |
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery NG Lamson, KC Fein, JP Gleeson, AN Newby, S Xian, K Cochran, ... Proceedings of the National Academy of Sciences 119 (33), e2207829119, 2022 | 18 | 2022 |
Long‐term daily oral administration of intestinal permeation enhancers is safe and effective in mice KC Fein, JP Gleeson, K Cochran, NG Lamson, R Doerfler, JR Melamed, ... Bioengineering & Translational Medicine, e10342, 2022 | 11 | 2022 |
Validation of a Caco-2 microfluidic Chip model for predicting intestinal absorption of BCS Class I-IV drugs SY Zhang, WSY Ong, N Subelzu, JP Gleeson International Journal of Pharmaceutics 656, 124089, 2024 | 7 | 2024 |