Overview on the current status of virtual high-throughput screening and combinatorial chemistry approaches in multi-target anticancer drug discovery; Part I GD Geromichalos, CE Alifieris, EG Geromichalou, DT Trafalis J buon 21 (4), 764-79, 2016 | 49 | 2016 |
Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL TF Kellici, MV Chatziathanasiadou, MS Lee, N Sayyad, EG Geromichalou, ... Organic & biomolecular chemistry 15 (37), 7956-7976, 2017 | 30 | 2017 |
Synthesis and evaluation of new steroidal lactam conjugates with aniline mustards as potential antileukemic therapeutics D Trafalis, E Geromichalou, P Dalezis, N Nikoleousakos, V Sarli Steroids 115, 1-8, 2016 | 30 | 2016 |
In vitro and in silico evaluation of the inhibitory effect of a curcumin-based oxovanadium (IV) complex on alkaline phosphatase activity and bacterial biofilm formation G Katsipis, V Tsalouxidou, E Halevas, E Geromichalou, G Geromichalos, ... Applied Microbiology and Biotechnology 105, 147-168, 2021 | 27 | 2021 |
Copper (II) complexes with non–steroidal anti–inflammatory drugs: Structural characterization, in vitro and in silico biological profile G Malis, E Geromichalou, GD Geromichalos, AG Hatzidimitriou, ... Journal of Inorganic Biochemistry 224, 111563, 2021 | 26 | 2021 |
Synthesis, structural determination, in vitro and in silico biological evaluation of divalent or trivalent cobalt complexes with indomethacin S Perontsis, E Geromichalou, F Perdih, AG Hatzidimitriou, ... Journal of Inorganic Biochemistry 212, 111213, 2020 | 19 | 2020 |
Zinc (II) complexes of 3, 5–dibromo–salicylaldehyde and α–diimines: Synthesis, characterization and in vitro and in silico biological profile A Zianna, E Geromichalou, G Geromichalos, AM Fiotaki, ... Journal of Inorganic Biochemistry 226, 111659, 2022 | 18 | 2022 |
Silver complexes with heterocyclic thioamide and tertiary arylphosphane ligands: Synthesis, crystal structures, in vitro and in silico antibacterial and cytotoxic activity, and … D Anastasiadou, E Geromichalou, E Tsavea, G Psomas, ... Journal of Inorganic Biochemistry 210, 111167, 2020 | 17 | 2020 |
Amplifying and broadening the cytotoxic profile of quercetin in cancer cell lines through bioconjugation MV Chatziathanasiadou, EG Geromichalou, N Sayyad, EI Vrettos, ... Amino Acids 50, 279-291, 2018 | 16 | 2018 |
In silico study of potential antiviral activity of copper (II) complexes with non–steroidal anti–inflammatory drugs on various SARS–CoV–2 target proteins EG Geromichalou, DT Trafalis, P Dalezis, G Malis, G Psomas, ... Journal of Inorganic Biochemistry 231, 111805, 2022 | 15 | 2022 |
Biocompatible silver (I) complexes with heterocyclic thioamide ligands for selective killing of cancer cells and high antimicrobial activity–A combined in vitro and in silico study D Varna, E Geromichalou, E Papachristou, R Papi, AG Hatzidimitriou, ... Journal of Inorganic Biochemistry 228, 111695, 2022 | 14 | 2022 |
Regioselective chemical and rapid enzymatic synthesis of a novel redox–Antiproliferative molecular hybrid E Geromichalou, N Sayyad, E Kyriakou, AV Chatzikonstantinou, ... European Journal of Medicinal Chemistry 96, 47-57, 2015 | 13 | 2015 |
A unique ternary Ce (III)-quercetin-phenanthroline assembly with antioxidant and anti-inflammatory properties E Halevas, S Matsia, A Hatzidimitriou, E Geromichalou, TA Papadopoulos, ... Journal of Inorganic Biochemistry 235, 111947, 2022 | 9 | 2022 |
Silver (i) complexes bearing heterocyclic thioamide ligands with NH 2 and CF 3 substituents: effect of ligand group substitution on antibacterial and anticancer properties D Varna, E Geromichalou, AG Hatzidimitriou, R Papi, G Psomas, ... Dalton Transactions 51 (24), 9412-9431, 2022 | 9 | 2022 |
Unraveling the binding mechanism of an Oxovanadium (IV)–Curcumin complex on albumin, DNA and DNA gyrase by in vitro and in silico studies and evaluation of its hemocompatibility DΙ Avgoulas, G Katsipis, E Halevas, EG Geromichalou, GD Geromichalos, ... Journal of Inorganic Biochemistry 221, 111402, 2021 | 9 | 2021 |
Antitumor activity of crocin, crocetin and safranal on murine P388 leukemia bearing mice P Dalezis, E Papageorgiou, E Geromichalou, G Geromichalus 3rd International symposium on saffron Forthcoming challenges in cultivation …, 2009 | 9 | 2009 |
In silico/in vitro study of hybrid D-modified steroidal alkylator anticancer activity using uridine phosphorylase as target protein GD Geromichalos, E Geromichalou, C Camoutsis, M Kontos, P Dalezis, ... Anticancer research 31 (3), 831-842, 2011 | 8 | 2011 |
Discovery of Steroidal Lactam Conjugates of POPAM-NH2 With Potent Anticancer Activity D Trafalis, P Dalezis, E Geromichalou, S Sagredou, E Sflakidou, M Voura, ... Future Medicinal Chemistry 12 (1), 19-35, 2020 | 7 | 2020 |
In silico approach for the evaluation of the potential antiviral activity of extra virgin olive oil (EVOO) bioactive constituents oleuropein and oleocanthal on spike … EG Geromichalou, GD Geromichalos Molecules 27 (21), 7572, 2022 | 6 | 2022 |
Cytocidal Antitumor Effects against Human Ovarian Cancer Cells Induced by B-Lactam Steroid Alkylators with Targeted Activity against Poly (ADP-Ribose) Polymerase (PARP) Enzymes … N Nikoleousakos, P Dalezis, A Polonifi, EG Geromichalou, S Sagredou, ... Biomedicines 9 (8), 1028, 2021 | 4 | 2021 |