| Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling J Nyffeler, C Willis, R Lougee, A Richard, K Paul-Friedman, JA Harrill Toxicology and Applied Pharmacology 389, 114876, 2020 | 110 | 2020 |
| Multiparameter toxicity assessment of novel DOPO-derived organophosphorus flame retardants C Hirsch, B Striegl, S Mathes, C Adlhart, M Edelmann, E Bono, S Gaan, ... Archives of toxicology 91, 407-425, 2017 | 83 | 2017 |
| Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay C Willis, J Nyffeler, J Harrill SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (7), 755-769, 2020 | 58 | 2020 |
| Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants J Nyffeler, C Karreman, H Leisner, YJ Kim, G Lee, T Waldmann, M Leist Alternatives to Animal Experimentation: ALTEX 34 (1), 75-94, 2017 | 51 | 2017 |
| Association study in siblings and case-controls of serotonin-and oxytocin-related genes with high functioning autism J Nyffeler, S Walitza, E Bobrowski, R Gundelfinger, E Grünblatt Journal of molecular psychiatry 2, 1-9, 2014 | 48 | 2014 |
| Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library J Nyffeler, X Dolde, A Krebs, K Pinto-Gil, M Pastor, M Behl, T Waldmann, ... Archives of toxicology 91, 3613-3632, 2017 | 45 | 2017 |
| Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling N Dreser, B Zimmer, C Dietz, E Sügis, G Pallocca, J Nyffeler, J Meisig, ... Neurotoxicology 50, 56-70, 2015 | 41 | 2015 |
| Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments J Nyffeler, C Willis, FR Harris, MJ Foster, B Chambers, M Culbreth, ... Toxicology and Applied Pharmacology 468, 116513, 2023 | 35 | 2023 |
| Normalization of data for viability and relative cell function curves A Krebs, J Nyffeler, J Rahnenführer, M Leist Alternatives to Animal Experimentation: ALTEX 35 (2), 268-271, 2018 | 33 | 2018 |
| A structure–activity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins J Nyffeler, P Chovancova, X Dolde, AK Holzer, V Purvanov, I Kindinger, ... Archives of toxicology 92, 1225-1247, 2018 | 29 | 2018 |
| Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data J Nyffeler, DE Haggard, C Willis, RW Setzer, R Judson, K Paul-Friedman, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (2), 292-308, 2021 | 28 | 2021 |
| Determination of benchmark concentrations and their statistical uncertainty for cytotoxicity test data and functional in vitro assays A Krebs, J Nyffeler, C Karreman, BZ Schmidt, F Kappenberg, J Mellert, ... ALTEX-Alternatives to animal experimentation 37 (1), 155-163, 2020 | 28 | 2020 |
| The synthetic peptide LyeTxI-b derived from Lycosa erythrognatha spider venom is cytotoxic to U-87 MG glioblastoma cells MAL Abdel-Salam, J Carvalho-Tavares, KS Gomes, A Teixeira-Carvalho, ... Amino Acids 51, 433-449, 2019 | 20 | 2019 |
| Impairment of human neural crest cell migration by prolonged exposure to interferon-beta G Pallocca, J Nyffeler, X Dolde, M Grinberg, G Gstraunthaler, T Waldmann, ... Archives of toxicology 91, 3385-3402, 2017 | 18 | 2017 |
| Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example J Nyffeler, C Willis, FR Harris, LW Taylor, R Judson, LJ Everett, JA Harrill Toxicology and Applied Pharmacology 444, 116032, 2022 | 17 | 2022 |
| Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities I Shah, J Bundy, B Chambers, LJ Everett, D Haggard, J Harrill, RS Judson, ... Chemical Research in Toxicology 35 (11), 1929-1949, 2022 | 13 | 2022 |
| An expert-driven literature review of “negative” chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation MM Martin, NC Baker, WK Boyes, KE Carstens, ME Culbreth, ME Gilbert, ... Neurotoxicology and Teratology 93, 107117, 2022 | 12 | 2022 |
| Time and space-resolved quantification of plasma membrane sialylation for measurements of cell function and neurotoxicity P Kranaster, C Karreman, JEGA Dold, A Krebs, M Funke, AK Holzer, ... Archives of Toxicology 94, 449-467, 2020 | 12 | 2020 |
| Stem cell microscopic image segmentation using supervised normalized cuts X Huang, C Li, M Shen, K Shirahama, J Nyffeler, M Leist, M Grzegorzek, ... 2016 IEEE International Conference on Image Processing (ICIP), 4140-4144, 2016 | 10 | 2016 |
| In vitro bioassays for monitoring drinking water quality of tap water, domestic filtration and bottled water BI Escher, J Blanco, J Caixach, D Cserbik, MJ Farré, C Flores, M König, ... Journal of Exposure Science & Environmental Epidemiology, 1-10, 2023 | 5 | 2023 |
Marcel LeistToxicology and Biomedicine, University of KonstanzVerifierad e-postadress på uni.kn
