The IL-4 receptor: signaling mechanisms and biologic functions K Nelms, AD Keegan, J Zamorano, JJ Ryan, WE Paul Annual review of immunology 17 (1), 701-738, 1999 | 2042 | 1999 |
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis CK Heazlewood, MC Cook, R Eri, GR Price, SB Tauro, D Taupin, ... PLoS medicine 5 (3), e54, 2008 | 845 | 2008 |
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis FW Quelle, K Shimoda, W Thierfelder, C Fischer, A Kim, SM Ruben, ... Molecular and cellular biology 15 (6), 3336-3343, 1995 | 440 | 1995 |
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth AD Keegan, K Nelms, M White, LM Wang, JH Pierce, WE Paul Cell 76 (5), 811-820, 1994 | 381 | 1994 |
Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis JE Jun, LE Wilson, CG Vinuesa, S Lesage, M Blery, LA Miosge, MC Cook, ... Immunity 18 (6), 751-762, 2003 | 341 | 2003 |
A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration J Chu, NA Hong, CA Masuda, BV Jenkins, KA Nelms, CC Goodnow, ... Proceedings of the National Academy of Sciences 106 (7), 2097-2103, 2009 | 256 | 2009 |
Growth and gene expression are predominantly controlled by distinct regions of the human IL-4 receptor JJ Ryan, LJ McReynolds, A Keegan, LH Wang, E Garfein, P Rothman, ... Immunity 4 (2), 123-132, 1996 | 225 | 1996 |
A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence G Li, R Vega, K Nelms, N Gekakis, C Goodnow, P McNamara, H Wu, ... PLoS genetics 3 (1), e8, 2007 | 224 | 2007 |
Fat Aussie—A New Alström Syndrome Mouse Showing a Critical Role for ALMS1 in Obesity, Diabetes, and Spermatogenesis T Arsov, DG Silva, MK O’Bryan, A Sainsbury, NJ Lee, C Kennedy, ... Molecular endocrinology 20 (7), 1610-1622, 2006 | 186 | 2006 |
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor P Papathanasiou, AC Perkins, BS Cobb, R Ferrini, R Sridharan, ... Immunity 19 (1), 131-144, 2003 | 173 | 2003 |
Interleukin 4 receptor: signaling mechanisms AD Keegan, K Nelms, LM Wang, JH Pierce, WE Paul Immunology Today 15 (9), 423-432, 1994 | 155 | 1994 |
Genome-wide ENU mutagenesis to reveal immune regulators KA Nelms, CC Goodnow Immunity 15 (3), 409-418, 2001 | 137 | 2001 |
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation K Nelms, AL Snow, J Hu-Li, WE Paul Immunity 9 (1), 13-24, 1998 | 131 | 1998 |
Interleukin 4 signals through two related pathways. A Pernis, B Witthuhn, AD Keegan, K Nelms, E Garfein, JN Ihle, WE Paul, ... Proceedings of the National Academy of Sciences 92 (17), 7971-7975, 1995 | 116 | 1995 |
Alternative splicing, gene localization, and binding of SH2-B to the insulin receptor kinase domain K Nelms, TJ O'neill, S Li, SR Hubbard, TA Gustafson, WE Paul Mammalian Genome 10, 1160-1167, 1999 | 103 | 1999 |
Contribution of the Box 1 and Box 2 motifs of cytokine receptors to Jak1 association and activation A Usacheva, R Sandoval, P Domanski, SV Kotenko, K Nelms, ... Journal of Biological Chemistry 277 (50), 48220-48226, 2002 | 76 | 2002 |
Molecular dissection of the mouse interleukin-4 promoter. KW Bruhn, K Nelms, JL Boulay, WE Paul, MJ Lenardo Proceedings of the National Academy of Sciences 90 (20), 9707-9711, 1993 | 75 | 1993 |
A genomic view of immunology AM Fahrer, JF Bazan, P Papathanasiou, KA Nelms, CC Goodnow Nature 409 (6822), 836-838, 2001 | 62 | 2001 |
Characterization of a mobile Stat6 activation motif in the human IL-4 receptor JJ Ryan, LJ McReynolds, H Huang, K Nelms, WE Paul The Journal of Immunology 161 (4), 1811-1821, 1998 | 56 | 1998 |
Interleukin-4 receptor signalling mechanisms and their biological significance K Nelms, H Huang, J Ryan, A Keegan, WE Paul Mechanisms of Lymphocyte Activation and Immune Regulation VII: Molecular …, 1998 | 53 | 1998 |