Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019 | 644 | 2019 |
PKA: a portrait of protein kinase dynamics SS Taylor, J Yang, J Wu, NM Haste, E Radzio-Andzelm, G Anand Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 259-269, 2004 | 455 | 2004 |
Dynamics of signaling by PKA SS Taylor, C Kim, D Vigil, NM Haste, J Yang, J Wu, GS Anand Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1754 (1-2), 25-37, 2005 | 326 | 2005 |
Structural basis for the inhibition mechanism of human cystathionine γ-lyase, an enzyme responsible for the production of H2S Q Sun, R Collins, S Huang, L Holmberg-Schiavone, GS Anand, CH Tan, ... Journal of Biological Chemistry 284 (5), 3076-3085, 2009 | 227 | 2009 |
cAMP activation of PKA defines an ancient signaling mechanism R Das, V Esposito, M Abu-Abed, GS Anand, SS Taylor, G Melacini Proceedings of the National Academy of Sciences 104 (1), 93-98, 2007 | 161 | 2007 |
The inner membrane histidine kinase EnvZ senses osmolality via helix‐coil transitions in the cytoplasm LC Wang, LK Morgan, P Godakumbura, LJ Kenney, GS Anand The EMBO journal 31 (11), 2648-2659, 2012 | 147 | 2012 |
SARS-CoV-2 S protein: ACE2 interaction reveals novel allosteric targets PV Raghuvamsi, NK Tulsian, F Samsudin, X Qian, K Purushotorman, ... Elife 10, e63646, 2021 | 124 | 2021 |
Evolution of allostery in the cyclic nucleotide binding module N Kannan, J Wu, GS Anand, S Yooseph, AF Neuwald, JC Venter, ... Genome biology 8, 1-13, 2007 | 122 | 2007 |
Salmonella enterica response regulator SsrB relieves H-NS silencing by displacing H-NS bound in polymerization mode and directly activates transcription D Walthers, Y Li, Y Liu, G Anand, J Yan, LJ Kenney Journal of Biological chemistry 286 (3), 1895-1902, 2011 | 118 | 2011 |
Activation of methylesterase CheB: evidence of a dual role for the regulatory domain GS Anand, PN Goudreau, AM Stock Biochemistry 37 (40), 14038-14047, 1998 | 118 | 1998 |
Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the RIα subunit of protein kinase A GS Anand, CA Hughes, JM Jones, SS Taylor, EA Komives Journal of molecular biology 323 (2), 377-386, 2002 | 114 | 2002 |
Identification of the protein kinase A regulatory RIα-catalytic subunit interface by amide H/2H exchange and protein docking GS Anand, D Law, JG Mandell, AN Snead, I Tsigelny, SS Taylor, LFT Eyck, ... Proceedings of the National Academy of Sciences 100 (23), 13264-13269, 2003 | 113 | 2003 |
Mapping intersubunit interactions of the regulatory subunit (RIα) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS) Y Hamuro, GS Anand, JS Kim, C Juliano, DD Stranz, SS Taylor, ... Journal of molecular biology 340 (5), 1185-1196, 2004 | 106 | 2004 |
Structure and dynamics of PKA signaling proteins. C Kim, D Vigil, G Anand, SS Taylor European journal of cell biology 85 (7), 651-654, 2006 | 91 | 2006 |
Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments M Hotchko, GS Anand, EA Komives, LF Ten Eyck Protein Science 15 (3), 583-601, 2006 | 89 | 2006 |
EnvZ/OmpR two-component signaling: an archetype system that can function noncanonically LJ Kenney, GS Anand EcoSal Plus 9 (1), 10.1128/ecosalplus. ESP-0001-2019, 2020 | 87 | 2020 |
Conformational changes in intact dengue virus reveal serotype-specific expansion XX Lim, A Chandramohan, XYE Lim, N Bag, KK Sharma, M Wirawan, ... Nature communications 8 (1), 14339, 2017 | 80 | 2017 |
Allosteric network of cAMP-dependent protein kinase revealed by mutation of Tyr204 in the P+ 1 loop J Yang, SM Garrod, MS Deal, GS Anand, VL Woods Jr, S Taylor Journal of molecular biology 346 (1), 191-201, 2005 | 78 | 2005 |
Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells S Higuchi, Q Lin, J Wang, TK Lim, SB Joshi, GS Anand, MCM Chung, ... Journal of bioscience and bioengineering 115 (3), 320-325, 2013 | 77 | 2013 |
Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design S Badireddy, G Yunfeng, M Ritchie, P Akamine, J Wu, CW Kim, SS Taylor, ... Molecular & Cellular Proteomics 10 (3), M110. 004390, 2011 | 77 | 2011 |