High Levels of Circulating Epinephrine Trigger Apical Cardiodepression in a β2-Adrenergic Receptor/Gi–Dependent Manner: A New Model of Takotsubo … H Paur, PT Wright, MB Sikkel, MH Tranter, C Mansfield, P O'gara, ... Circulation 126 (6), 697-706, 2012 | 849 | 2012 |
Trends in mortality from ischemic heart disease and cerebrovascular disease in Europe: 1980 to 2009 A Hartley, DC Marshall, JD Salciccioli, MB Sikkel, M Maruthappu, ... Circulation 133 (20), 1916-1926, 2016 | 365 | 2016 |
Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling PT Wright, VO Nikolaev, T O'Hara, I Diakonov, A Bhargava, S Tokar, ... Journal of molecular and cellular cardiology 67, 38-48, 2014 | 136 | 2014 |
Hierarchical statistical techniques are necessary to draw reliable conclusions from analysis of isolated cardiomyocyte studies MB Sikkel, DP Francis, J Howard, F Gordon, C Rowlands, NS Peters, ... Cardiovascular research 113 (14), 1743-1752, 2017 | 133 | 2017 |
Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis L Roca-Alonso, L Castellano, A Mills, AF Dabrowska, MB Sikkel, ... Cell death & disease 6 (5), e1754-e1754, 2015 | 130 | 2015 |
Respiratory syncytial virus persistence in chronic obstructive pulmonary disease MB Sikkel, JK Quint, P Mallia, JA Wedzicha, SL Johnston The Pediatric infectious disease journal 27 (10), S63-S70, 2008 | 129 | 2008 |
Plasticity of Surface Structures and β2-Adrenergic Receptor Localization in Failing Ventricular Cardiomyocytes During Recovery From Heart Failure AR Lyon, VO Nikolaev, M Miragoli, MB Sikkel, H Paur, L Benard, JS Hulot, ... Circulation: Heart Failure 5 (3), 357-365, 2012 | 126 | 2012 |
Microdomain-specific modulation of L-type calcium channels leads to triggered ventricular arrhythmia in heart failure JL Sanchez-Alonso, A Bhargava, T O’Hara, AV Glukhov, ... Circulation research 119 (8), 944-955, 2016 | 121 | 2016 |
The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2 ML Bannister, NL Thomas, MB Sikkel, S Mukherjee, C Maxwell, ... Circulation Research 116 (8), 1324-1335, 2015 | 104 | 2015 |
High-speed 2D and 3D fluorescence microscopy of cardiac myocytes S Kumar, D Wilding, MB Sikkel, AR Lyon, KT MacLeod, C Dunsby Optics express 19 (15), 13839-13847, 2011 | 101 | 2011 |
Direct evidence for microdomain-specific localization and remodeling of functional L-type calcium channels in rat and human atrial myocytes AV Glukhov, M Balycheva, JL Sanchez-Alonso, Z Ilkan, A Alvarez-Laviada, ... Circulation 132 (25), 2372-2384, 2015 | 98 | 2015 |
Flecainide reduces Ca2+ spark and wave frequency via inhibition of the sarcolemmal sodium current MB Sikkel, TP Collins, C Rowlands, M Shah, P O'Gara, AJ Williams, ... Cardiovascular research 98 (2), 286-296, 2013 | 90 | 2013 |
Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease C Toepfer, V Caorsi, T Kampourakis, MB Sikkel, T West, JC Leung, ... Biophysical Journal 104 (2), 309a-310a, 2013 | 89 | 2013 |
Investigation of cardiac fibroblasts using myocardial slices F Perbellini, SA Watson, M Scigliano, S Alayoubi, S Tkach, I Bardi, ... Cardiovascular research 114 (1), 77-89, 2018 | 82 | 2018 |
Efficacy and safety of same-day discharge for atrial fibrillation ablation MW Deyell, RA Leather, L Macle, J Forman, P Khairy, R Zhang, L Ding, ... Clinical Electrophysiology 6 (6), 609-619, 2020 | 78 | 2020 |
T-tubule remodelling disturbs localized β2-adrenergic signalling in rat ventricular myocytes during the progression of heart failure S Schobesberger, P Wright, S Tokar, A Bhargava, C Mansfield, ... Cardiovascular research 113 (7), 770-782, 2017 | 66 | 2017 |
SERCA2a gene therapy in heart failure: an anti‐arrhythmic positive inotrope MB Sikkel, C Hayward, KT MacLeod, SE Harding, AR Lyon British journal of pharmacology 171 (1), 38-54, 2014 | 65 | 2014 |
Visualizing localized reentry with ultra–high density mapping in iatrogenic atrial tachycardia: beware pseudo-reentry V Luther, M Sikkel, N Bennett, F Guerrero, K Leong, N Qureshi, FS Ng, ... Circulation: Arrhythmia and Electrophysiology 10 (4), e004724, 2017 | 64 | 2017 |
Microtubule-dependent mitochondria alignment regulates calcium release in response to nanomechanical stimulus in heart myocytes M Miragoli, JL Sanchez-Alonso, A Bhargava, PT Wright, M Sikkel, ... Cell reports 14 (1), 140-151, 2016 | 63 | 2016 |
Ectopy-triggering ganglionated plexuses ablation to prevent atrial fibrillation: GANGLIA-AF study MY Kim, C Coyle, DR Tomlinson, MB Sikkel, A Sohaib, V Luther, ... Heart Rhythm 19 (4), 516-524, 2022 | 54 | 2022 |