| A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels W Zheng, EO Gracheva, SN Bagriantsev Elife 8, e44003, 2019 | 83 | 2019 |
| The mechanosensory transduction machinery in inner ear hair cells W Zheng, JR Holt Annual review of biophysics 50 (1), 31-51, 2021 | 77 | 2021 |
| Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels W Zheng, X Yang, R Hu, R Cai, L Hofmann, Z Wang, Q Hu, X Liu, ... Nature communications 9 (1), 2302, 2018 | 68 | 2018 |
| Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors W Zheng, YA Nikolaev, EO Gracheva, SN Bagriantsev Proceedings of the National Academy of Sciences 116 (35), 17547-17555, 2019 | 55 | 2019 |
| Direct binding between pre-S1 and TRP-like domains in TRPP channels mediates gating and functional regulation by PIP2 W Zheng, R Cai, L Hofmann, V Nesin, Q Hu, W Long, M Fatehi, X Liu, ... Cell reports 22 (6), 1560-1573, 2018 | 49 | 2018 |
| TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels W Zheng, S Rawson, Z Shen, E Tamilselvan, HE Smith, J Halford, C Shen, ... Neuron 111 (20), 3195-3210. e7, 2023 | 43 | 2023 |
| The S4–S5 linker–gearbox of TRP channel gating L Hofmann, H Wang, W Zheng, SE Philipp, P Hidalgo, A Cavalié, ... Cell Calcium 67, 156-165, 2017 | 42 | 2017 |
| Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca2+ S Hussein, W Zheng, C Dyte, Q Wang, JW Yang, F Zhang, J Tang, Y Cao, ... Scientific reports 5 (1), 15752, 2015 | 42 | 2015 |
| Identification and characterization of hydrophobic gate residues in TRP channels W Zheng, R Hu, R Cai, L Hofmann, Q Hu, M Fatehi, W Long, T Kong, ... The FASEB Journal 32 (2), 639-653, 2018 | 41 | 2018 |
| pH regulates potassium conductance and drives a constitutive proton current in human TMEM175 W Zheng, C Shen, L Wang, S Rawson, WJ Xie, C Nist-Lund, J Wu, Z Shen, ... Science advances 8 (12), eabm1568, 2022 | 35 | 2022 |
| Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction J Yang, Q Wang, W Zheng, J Tuli, Q Li, Y Wu, S Hussein, XQ Dai, ... Journal of Biological Chemistry 287 (9), 6551-6561, 2012 | 34 | 2012 |
| Autoinhibition of TRPV6 Channel and Regulation by PIP2 R Cai, X Liu, R Zhang, L Hofmann, W Zheng, MR Amin, L Wang, Q Hu, ... Iscience 23 (9), 2020 | 22 | 2020 |
| Ethnic differences in genetic ion channelopathies associated with sudden cardiac death: a systematic review and meta-analysis T Kong, J Feulefack, K Ruether, F Shen, W Zheng, XZ Chen, C Sergi Annals of Clinical & Laboratory Science 47 (4), 481-490, 2017 | 21 | 2017 |
| Regulation of TRPP3 channel function by N-terminal domain palmitoylation and phosphorylation W Zheng, JW Yang, E Beauchamp, R Cai, S Hussein, L Hofmann, Q Li, ... Journal of Biological Chemistry 291 (49), 25678-25691, 2016 | 21 | 2016 |
| A novel PKD2L1 C-terminal domain critical for trimerization and channel function W Zheng, S Hussein, JW Yang, J Huang, F Zhang, S Hernandez-Anzaldo, ... Scientific reports 5 (1), 9460, 2015 | 21 | 2015 |
| Far upstream element-binding protein 1 binds the 3′ untranslated region of PKD2 and suppresses its translation W Zheng, F Shen, R Hu, B Roy, JW Yang, Q Wang, F Zhang, JC King, ... Journal of the American Society of Nephrology 27 (9), 2645-2657, 2016 | 20 | 2016 |
| Filamin-a increases the stability and plasma membrane expression of polycystin-2 Q Wang, W Zheng, Z Wang, JW Yang, S Hussein, J Tang, XZ Chen PLoS One 10 (4), e0123018, 2015 | 18 | 2015 |
| Expression of polycystins and fibrocystin on primary cilia of lung cells Q Hu, Y Wu, J Tang, W Zheng, Q Wang, D Nahirney, M Duszyk, S Wang, ... Biochemistry and Cell Biology 92 (6), 547-554, 2014 | 18 | 2014 |
| Translational up‐regulation of polycystic kidney disease protein PKD2 by endoplasmic reticulum stress J Yang, W Zheng, Q Wang, C Lara, S Hussein, XZ Chen The FASEB Journal 27 (12), 4998-5009, 2013 | 18 | 2013 |
| Zebrafish TARP Cacng2 is required for the expression and normal development of AMPA receptors at excitatory synapses B Roy, KT Ahmed, ME Cunningham, J Ferdous, R Mukherjee, W Zheng, ... Developmental neurobiology 76 (5), 487-506, 2016 | 8 | 2016 |
