ติดตาม
Joseph T Clark
Joseph T Clark
Graduate Student, University of Pennsylvania
ยืนยันอีเมลแล้วที่ alumni.upenn.edu
ชื่อ
อ้างโดย
อ้างโดย
ปี
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
A Hendel, RO Bak, JT Clark, AB Kennedy, DE Ryan, S Roy, I Steinfeld, ...
Nature biotechnology 33 (9), 985-989, 2015
12742015
Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing
A Hendel, EJ Kildebeck, EJ Fine, JT Clark, N Punjya, V Sebastiano, ...
Cell reports 7 (1), 293-305, 2014
1492014
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection
JA Perry, L Shallberg, JT Clark, JA Gullicksrud, JH DeLong, BB Douglas, ...
Nature immunology 23 (5), 743-756, 2022
712022
The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses
L Chen, DA Christian, JA Kochanowsky, AT Phan, JT Clark, S Wang, ...
Journal of Experimental Medicine 217 (3), e20181757, 2020
632020
CRISPR/Cas9 genome engineering in engraftable human brain-derived neural stem cells
DP Dever, SG Scharenberg, J Camarena, EJ Kildebeck, JT Clark, ...
Iscience 15, 524-535, 2019
372019
The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell
JE Dumaine, A Sateriale, AR Gibson, AG Reddy, JA Gullicksrud, ...
Elife 10, e70451, 2021
342021
IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii
JT Clark, DA Christian, JA Gullicksrud, JA Perry, J Park, M Jacquet, ...
Elife 10, e65614, 2021
322021
cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory
DA Christian, TA Adams, LA Shallberg, AT Phan, TE Smith, M Abraha, ...
Science immunology 7 (75), eabq7432, 2022
272022
Chemically modified guide RNAs for CRISPR/CAS-mediated gene regulation
MH Porteus, A Hendel, J Clark, RO Bak, DE Ryan, DJ Dellinger, R Kaiser, ...
US Patent 11,306,309, 2022
212022
PD-1 and CTLA-4 exert additive control of effector regulatory T cells at homeostasis
JA Perry, Z Lanzar, JT Clark, AP Hart, BB Douglas, L Shallberg, K O'Dea, ...
Frontiers in Immunology 14, 818, 2023
112023
IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii
JT Clark, OE Weizman, DL Aldridge, LA Shallberg, J Eberhard, Z Lanzar, ...
Cell reports 42 (3), 2023
82023
PD-L1–PD-1 interactions limit effector Treg cell populations at homeostasis and during infection
JA Perry, JT Clark, J Gullicksrud, J DeLong, L Shallberg, B Douglas, ...
bioRxiv, 2020.12. 09.416990, 2020
12020
Genome editing of human neural stem cells using nucleases
MH Porteus, EJ Kildebeck, DP Dever, JT Clark, A Tsukamoto, N Uchida
US Patent App. 18/092,911, 2023
2023
PD-1 and CTLA-4 exert additive control of effector regulatory T cells
JA Perry, Z Lanzar, JT Clark, AP Hart, BB Douglas, L Shallberg, K O’Dea, ...
bioRxiv, 2022.07. 22.501159, 2022
2022
PD-1 LIMITS TREG IMMUNE SUPPRESSION DURING ACUTE TOXOPLASMOSIS
J Perry, JT Clark, J Gullicksrud, J DeLong, L Shallberg, B Douglas, A Hart, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 449-449, 2021
2021
Understanding the Role of the IL-1 Family Cytokines IL-18 and IL-33 in Protective and Pathological Responses to Toxoplasma gondii
JT Clark
University of Pennsylvania, 2021
2021
PD-1 signaling impacts T cell function during the early phase of infection with Toxoplasma gondii
JA Perry, J Delong, J Clark, J Park, J Gullicksrud, L Shallberg, C Konradt, ...
The Journal of Immunology 202 (1_Supplement), 122.5-122.5, 2019
2019
IL-33 potentiates the inflammatory response to Toxoplasma gondii
JT Clark, J Park, C Konradt, M Jacquet, C Hunter
CYTOKINE 100, 46-46, 2017
2017
Chemically synthesized modified guide RNAs enhance CRISPR/cas9 genome editing
J Myerson, AB Kennedy, DE Ryan, SM Phadnis, CW Yung, RO Bak, ...
Synthetic Biology: Engineering, Evolution, and Design Conference 2016, SEED …, 2016
2016
ระบบไม่สามารถดำเนินการได้ในขณะนี้ โปรดลองใหม่อีกครั้งในภายหลัง
บทความ 1–19