| Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM TV Lanz, RC Brewer, PP Ho, JS Moon, KM Jude, D Fernandez, ... Nature 603 (7900), 321-327, 2022 | 682 | 2022 |
| De novo design of potent and selective mimics of IL-2 and IL-15 DA Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, ... Nature 565 (7738), 186-191, 2019 | 493 | 2019 |
| CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer K Weiskopf, NS Jahchan, PJ Schnorr, S Cristea, AM Ring, RL Maute, ... The Journal of clinical investigation 126 (7), 2610-2620, 2016 | 443 | 2016 |
| Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 383 | 2022 |
| Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes JT Sockolosky, E Trotta, G Parisi, L Picton, LL Su, AC Le, A Chhabra, ... Science 359 (6379), 1037-1042, 2018 | 340 | 2018 |
| Structural basis for chemokine recognition and activation of a viral G protein–coupled receptor JS Burg, JR Ingram, AJ Venkatakrishnan, KM Jude, A Dukkipati, ... Science 347 (6226), 1113-1117, 2015 | 335 | 2015 |
| Structural basis for Notch1 engagement of Delta-like 4 VC Luca, KM Jude, NW Pierce, MV Nachury, S Fischer, KC Garcia Science 347 (6224), 847-853, 2015 | 315 | 2015 |
| Isolation of a structural mechanism for uncoupling T cell receptor signaling from peptide-MHC binding LV Sibener, RA Fernandes, EM Kolawole, CB Carbone, F Liu, D McAffee, ... Cell 174 (3), 672-687. e27, 2018 | 296 | 2018 |
| Antibodies to interleukin-2 elicit selective T cell subset potentiation through distinct conformational mechanisms JB Spangler, J Tomala, VC Luca, KM Jude, S Dong, AM Ring, P Votavova, ... Immunity 42 (5), 815-825, 2015 | 252 | 2015 |
| A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism E Trotta, PH Bessette, SL Silveria, LK Ely, KM Jude, DT Le, CR Holst, ... Nature medicine 24 (7), 1005-1014, 2018 | 199 | 2018 |
| Structure of the IFNγ receptor complex guides design of biased agonists JL Mendoza, NK Escalante, KM Jude, J Sotolongo Bellon, L Su, ... Nature 567 (7746), 56-60, 2019 | 146 | 2019 |
| Topological control of cytokine receptor signaling induces differential effects in hematopoiesis K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ... Science 364 (6442), eaav7532, 2019 | 133 | 2019 |
| Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells CR Glassman, YK Mathiharan, KM Jude, L Su, O Panova, PJ Lupardus, ... Cell 184 (4), 983-999. e24, 2021 | 119 | 2021 |
| The IFN-λ-IFN-λR1-IL-10Rβ complex reveals structural features underlying type III IFN functional plasticity JL Mendoza, WM Schneider, HH Hoffmann, K Vercauteren, KM Jude, ... Immunity 46 (3), 379-392, 2017 | 116 | 2017 |
| Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle KM Jude, SK Wright, C Tu, DN Silverman, RE Viola, DW Christianson Biochemistry 41 (8), 2485-2491, 2002 | 113 | 2002 |
| Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation CR Glassman, N Tsutsumi, RA Saxton, PJ Lupardus, KM Jude, KC Garcia Science 376 (6589), 163-169, 2022 | 112 | 2022 |
| Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling N Tsutsumi, S Mukherjee, D Waghray, CY Janda, KM Jude, Y Miao, ... elife 9, e58464, 2020 | 103 | 2020 |
| Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with “two-prong” inhibitors reveal the molecular basis of high affinity KM Jude, AL Banerjee, MK Haldar, S Manokaran, B Roy, S Mallik, ... Journal of the American Chemical Society 128 (9), 3011-3018, 2006 | 103 | 2006 |
| Tuning T cell receptor sensitivity through catch bond engineering X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ... Science 376 (6589), eabl5282, 2022 | 95 | 2022 |
| Autoimmunity-associated T cell receptors recognize HLA-B* 27-bound peptides X Yang, LI Garner, IV Zvyagin, MA Paley, EA Komech, KM Jude, X Zhao, ... Nature 612 (7941), 771-777, 2022 | 93 | 2022 |
K. Christopher GarciaStanford University/HHMIยืนยันอีเมลแล้วที่ stanford.edu
