Association of BRCA1-and BRCA2-deficiency with mutation burden, expression of PD-L1/PD-1, immune infiltrates, and T cell-inflamed signature in breast cancer WX Wen, CO Leong PLoS One 14 (4), e0215381, 2019 | 102 | 2019 |
Human bone marrow organoids for disease modeling, discovery, and validation of therapeutic targets in hematologic malignancies AO Khan, A Rodriguez-Romera, JS Reyat, AA Olijnik, M Colombo, ... Cancer discovery 13 (2), 364-385, 2023 | 90 | 2023 |
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development A Roy, G Wang, D Iskander, S O’Byrne, N Elliott, J O’Sullivan, G Buck, ... Cell Reports 36 (11), 2021 | 64 | 2021 |
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution A Rodriguez-Meira, R Norfo, S Wen, AL Chédeville, H Rahman, ... Nature genetics 55 (9), 1531-1541, 2023 | 62 | 2023 |
Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation WX Wen, JSS Soo, PY Kwan, E Hong, TF Khang, S Mariapun, CSM Lee, ... Breast Cancer Research 18, 1-9, 2016 | 60 | 2016 |
Repurposing pentoxifylline for the treatment of fibrosis: an overview WX Wen, SY Lee, R Siang, RY Koh Advances in Therapy 34, 1245-1269, 2017 | 59 | 2017 |
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort J Li, WX Wen, M Eklund, A Kvist, M Eriksson, HN Christensen, ... International journal of cancer 144 (5), 1195-1204, 2019 | 51 | 2019 |
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia WX Wen, J Allen, KN Lai, S Mariapun, SN Hasan, PS Ng, DSC Lee, ... Journal of medical genetics 55 (2), 97-103, 2018 | 47 | 2018 |
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia E Louka, B Povinelli, A Rodriguez-Meira, G Buck, WX Wen, G Wang, ... Journal of Experimental Medicine 218 (2), e20180853, 2021 | 33 | 2021 |
Differential burden of rare and common variants on tumor characteristics, survival, and mode of detection in breast cancer J Li, E Ugalde-Morales, WX Wen, B Decker, M Eriksson, A Torstensson, ... Cancer Research 78 (21), 6329-6338, 2018 | 27 | 2018 |
Evaluation of germline BRCA1 and BRCA2 mutations in a multi-ethnic Asian cohort of ovarian cancer patients HN Hasmad, KN Lai, WX Wen, DJ Park, T Nguyen-Dumont, PCE Kang, ... Gynecologic oncology 141 (2), 318-322, 2016 | 22 | 2016 |
VALERIE: visual-based inspection of alternative splicing events at single-cell resolution WX Wen, AJ Mead, S Thongjuea PLOS Computational Biology 16 (9), e1008195, 2020 | 19 | 2020 |
Technological advances and computational approaches for alternative splicing analysis in single cells WX Wen, AJ Mead, S Thongjuea Computational and structural biotechnology journal 18, 332-343, 2020 | 19 | 2020 |
MARVEL: an integrated alternative splicing analysis platform for single-cell RNA sequencing data WX Wen, AJ Mead, S Thongjuea Nucleic Acids Research 51 (5), e29-e29, 2023 | 17 | 2023 |
Identification of germline alterations in breast cancer predisposition genes among Malaysian breast cancer patients using panel testing PS Ng, WX Wen, MZH Fadlullah, SY Yoon, SY Lee, MK Thong, CH Yip, ... Clinical genetics 90 (4), 315-323, 2016 | 17 | 2016 |
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation C Di Genua, R Norfo, A Rodriguez-Meira, WX Wen, R Drissen, ... haematologica 104 (11), 2215, 2019 | 14 | 2019 |
Processing single-cell RNA-seq datasets using SingCellaR G Wang, WX Wen, AJ Mead, A Roy, B Psaila, S Thongjuea STAR protocols 3 (2), 101266, 2022 | 10 | 2022 |
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis R Li, M Colombo, G Wang, A Rodriguez-Romera, C Benlabiod, NJ Jooss, ... Science translational medicine 16 (768), eadj7552, 2024 | 8 | 2024 |
Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences OS Burren, RS Dhindsa, SVV Deevi, S Wen, A Nag, J Mitchell, F Hu, ... Nature Genetics 56 (9), 1832-1840, 2024 | 7 | 2024 |
KIR genotype and haplotype frequencies in the multi-ethnic population of Malaysia WF Kevin-Tey, WX Wen, PC Bee, HS Eng, KW Ho, SM Tan, NA Anuar, ... Human Immunology 84 (3), 172-185, 2023 | 5 | 2023 |