ติดตาม
Sean Wen
Sean Wen
ยืนยันอีเมลแล้วที่ astrazeneca.com
ชื่อ
อ้างโดย
อ้างโดย
ปี
Association of BRCA1-and BRCA2-deficiency with mutation burden, expression of PD-L1/PD-1, immune infiltrates, and T cell-inflamed signature in breast cancer
WX Wen, CO Leong
PLoS One 14 (4), e0215381, 2019
1022019
Human bone marrow organoids for disease modeling, discovery, and validation of therapeutic targets in hematologic malignancies
AO Khan, A Rodriguez-Romera, JS Reyat, AA Olijnik, M Colombo, ...
Cancer discovery 13 (2), 364-385, 2023
902023
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development
A Roy, G Wang, D Iskander, S O’Byrne, N Elliott, J O’Sullivan, G Buck, ...
Cell Reports 36 (11), 2021
642021
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
A Rodriguez-Meira, R Norfo, S Wen, AL Chédeville, H Rahman, ...
Nature genetics 55 (9), 1531-1541, 2023
622023
Germline APOBEC3B deletion is associated with breast cancer risk in an Asian multi-ethnic cohort and with immune cell presentation
WX Wen, JSS Soo, PY Kwan, E Hong, TF Khang, S Mariapun, CSM Lee, ...
Breast Cancer Research 18, 1-9, 2016
602016
Repurposing pentoxifylline for the treatment of fibrosis: an overview
WX Wen, SY Lee, R Siang, RY Koh
Advances in Therapy 34, 1245-1269, 2017
592017
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
J Li, WX Wen, M Eklund, A Kvist, M Eriksson, HN Christensen, ...
International journal of cancer 144 (5), 1195-1204, 2019
512019
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
WX Wen, J Allen, KN Lai, S Mariapun, SN Hasan, PS Ng, DSC Lee, ...
Journal of medical genetics 55 (2), 97-103, 2018
472018
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
E Louka, B Povinelli, A Rodriguez-Meira, G Buck, WX Wen, G Wang, ...
Journal of Experimental Medicine 218 (2), e20180853, 2021
332021
Differential burden of rare and common variants on tumor characteristics, survival, and mode of detection in breast cancer
J Li, E Ugalde-Morales, WX Wen, B Decker, M Eriksson, A Torstensson, ...
Cancer Research 78 (21), 6329-6338, 2018
272018
Evaluation of germline BRCA1 and BRCA2 mutations in a multi-ethnic Asian cohort of ovarian cancer patients
HN Hasmad, KN Lai, WX Wen, DJ Park, T Nguyen-Dumont, PCE Kang, ...
Gynecologic oncology 141 (2), 318-322, 2016
222016
VALERIE: visual-based inspection of alternative splicing events at single-cell resolution
WX Wen, AJ Mead, S Thongjuea
PLOS Computational Biology 16 (9), e1008195, 2020
192020
Technological advances and computational approaches for alternative splicing analysis in single cells
WX Wen, AJ Mead, S Thongjuea
Computational and structural biotechnology journal 18, 332-343, 2020
192020
MARVEL: an integrated alternative splicing analysis platform for single-cell RNA sequencing data
WX Wen, AJ Mead, S Thongjuea
Nucleic Acids Research 51 (5), e29-e29, 2023
172023
Identification of germline alterations in breast cancer predisposition genes among Malaysian breast cancer patients using panel testing
PS Ng, WX Wen, MZH Fadlullah, SY Yoon, SY Lee, MK Thong, CH Yip, ...
Clinical genetics 90 (4), 315-323, 2016
172016
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation
C Di Genua, R Norfo, A Rodriguez-Meira, WX Wen, R Drissen, ...
haematologica 104 (11), 2215, 2019
142019
Processing single-cell RNA-seq datasets using SingCellaR
G Wang, WX Wen, AJ Mead, A Roy, B Psaila, S Thongjuea
STAR protocols 3 (2), 101266, 2022
102022
A proinflammatory stem cell niche drives myelofibrosis through a targetable galectin-1 axis
R Li, M Colombo, G Wang, A Rodriguez-Romera, C Benlabiod, NJ Jooss, ...
Science translational medicine 16 (768), eadj7552, 2024
82024
Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences
OS Burren, RS Dhindsa, SVV Deevi, S Wen, A Nag, J Mitchell, F Hu, ...
Nature Genetics 56 (9), 1832-1840, 2024
72024
KIR genotype and haplotype frequencies in the multi-ethnic population of Malaysia
WF Kevin-Tey, WX Wen, PC Bee, HS Eng, KW Ho, SM Tan, NA Anuar, ...
Human Immunology 84 (3), 172-185, 2023
52023
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