Design, synthesis, anticancer evaluation, enzymatic assays, and a molecular modeling study of novel pyrazole–indole hybrids AS Hassan, GO Moustafa, HM Awad, ES Nossier, MF Mady ACS omega 6 (18), 12361-12374, 2021 | 100 | 2021 |
Antibacterial evaluation, in silico characters and molecular docking of Schiff bases derived from 5-aminopyrazoles AS Hassan, AA Askar, ES Nossier, AM Naglah, GO Moustafa, MA Al-Omar Molecules 24 (17), 3130, 2019 | 92 | 2019 |
New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies IMM Othman, ZM Alamshany, NY Tashkandi, MAM Gad-Elkareem, ... Bioorganic chemistry 114, 105078, 2021 | 82 | 2021 |
Design, synthesis and molecular docking of new pyrazole-thiazolidinones as potent anti-inflammatory and analgesic agents with TNF-α inhibitory activity SS Abd El-Karim, HS Mohamed, MF Abdelhameed, AEGE Amr, ... Bioorganic chemistry 111, 104827, 2021 | 80 | 2021 |
Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR RR Khattab, AK Alshamari, AA Hassan, HH Elganzory, WA El-Sayed, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 504-516, 2021 | 74 | 2021 |
New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2 IA Seliem, SS Panda, AS Girgis, Y Moatasim, A Kandeil, A Mostafa, MA Ali, ... Bioorganic Chemistry 114, 105117, 2021 | 70 | 2021 |
Synthesis, antimicrobial activity and molecular docking of novel thiourea derivatives tagged with thiadiazole, imidazole and triazine moieties as potential DNA gyrase and … HE Hashem, AEGE Amr, ES Nossier, EA Elsayed, EM Azmy Molecules 25 (12), 2766, 2020 | 70 | 2020 |
Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase DH Dawood, ES Nossier, MM Ali, AE Mahmoud Bioorganic chemistry 101, 103916, 2020 | 69 | 2020 |
Design and synthesis of novel pyrazole-substituted different nitrogenous heterocyclic ring systems as potential anti-inflammatory agents ES Nossier, HH Fahmy, NM Khalifa, WI El-Eraky, MA Baset Molecules 22 (4), 512, 2017 | 67 | 2017 |
Design, synthesis and docking studies of novel macrocyclic pentapeptides as anticancer multi-targeted kinase inhibitors AEGE Amr, MH Abo-Ghalia, GO Moustafa, MA Al-Omar, ES Nossier, ... Molecules 23 (10), 2416, 2018 | 63 | 2018 |
Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies IMM Othman, MAM Gad-Elkareem, M El-Naggar, ES Nossier, AEGE Amr Journal of enzyme inhibition and medicinal chemistry 34 (1), 1259-1270, 2019 | 60 | 2019 |
Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold HSA Elzahabi, ES Nossier, NM Khalifa, RA Alasfoury, MA El-Manawaty Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 546-557, 2018 | 58 | 2018 |
Design, synthesis, and molecular docking study of novel heterocycles incorporating 1, 3, 4-thiadiazole moiety as potential antimicrobial and anticancer agents M El-Naggar, HA Sallam, SS Shaban, SS Abdel-Wahab, AEG E. Amr, ... Molecules 24 (6), 1066, 2019 | 57 | 2019 |
New Benzimidazole-, 1,2,4-Triazole-, and 1,3,5-Triazine-Based Derivatives as Potential EGFRWT and EGFRT790M Inhibitors: Microwave-Assisted Synthesis … HE Hashem, AEGE Amr, ES Nossier, MM Anwar, EM Azmy ACS omega 7 (8), 7155-7171, 2022 | 56 | 2022 |
Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi … IMM Othman, ZM Alamshany, NY Tashkandi, MAM Gad-Elkareem, ... RSC advances 12 (1), 561-577, 2022 | 55 | 2022 |
Synthesis, docking studies, and in vitro evaluation of some novel thienopyridines and fused thienopyridine–quinolines as antibacterial agents and DNA gyrase inhibitors EM Mohi El-Deen, EA Abd El-Meguid, S Hasabelnaby, EA Karam, ... Molecules 24 (20), 3650, 2019 | 54 | 2019 |
Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities HH Fahmy, NM Khalifa, MMF Ismail, HM El-Sahrawy, ES Nossier Molecules 21 (3), 271, 2016 | 54 | 2016 |
Design, synthesis, anticancer evaluation and molecular modeling of novel estrogen derivatives AEGE Amr, EA Elsayed, MA Al-Omar, HO Badr Eldin, ES Nossier, ... Molecules 24 (3), 416, 2019 | 51 | 2019 |
Design, Docking, and Synthesis of Some New Pyrazoline and Pyranopyrazole Derivatives as Anti‐inflammatory Agents MMF Ismail, NM Khalifa, HH Fahmy, ES Nossier, MM Abdulla Journal of Heterocyclic Chemistry 51 (2), 450-458, 2014 | 47 | 2014 |
Novel heterocyclic hybrids of pyrazole targeting dihydrofolate reductase: design, biological evaluation and in silico studies IMM Othman, MAM Gad-Elkareem, AEGE Amr, MA Al-Omar, ES Nossier, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1491-1502, 2020 | 46 | 2020 |