| L1 drives IFN in senescent cells and promotes age-associated inflammation M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ... Nature 566 (7742), 73-78, 2019 | 999 | 2019 |
| LINE1 derepression in aged wild-type and SIRT6-deficient mice drives inflammation M Simon, M Van Meter, J Ablaeva, Z Ke, RS Gonzalez, T Taguchi, ... Cell metabolism 29 (4), 871-885. e5, 2019 | 401 | 2019 |
| SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species X Tian, D Firsanov, Z Zhang, Y Cheng, L Luo, G Tombline, R Tan, ... Cell 177 (3), 622-638. e22, 2019 | 291 | 2019 |
| DNA damage and repair in age-related inflammation Y Zhao, M Simon, A Seluanov, V Gorbunova Nature Reviews Immunology 23 (2), 75-89, 2023 | 169 | 2023 |
| JNK phosphorylates SIRT6 to stimulate DNA double-strand break repair in response to oxidative stress by recruiting PARP1 to DNA breaks M Van Meter, M Simon, G Tombline, A May, TD Morello, BP Hubbard, ... Cell reports 16 (10), 2641-2650, 2016 | 146 | 2016 |
| Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants M Simon, P Sarkies, K Ikegami, AL Doebley, LD Goldstein, J Mitchell, ... Cell reports 7 (3), 762-773, 2014 | 136 | 2014 |
| SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170 S Rezazadeh, D Yang, G Tombline, M Simon, SP Regan, A Seluanov, ... Nucleic acids research 47 (15), 7914-7928, 2019 | 81 | 2019 |
| Caenorhabditis elegans RSD-2 and RSD-6 promote germ cell immortality by maintaining small interfering RNA populations A Sakaguchi, P Sarkies, M Simon, AL Doebley, LD Goldstein, A Hedges, ... Proceedings of the National Academy of Sciences 111 (41), E4323-E4331, 2014 | 58 | 2014 |
| Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation JY Lu, M Simon, Y Zhao, J Ablaeva, N Corson, Y Choi, KLYH Yamada, ... Cell Metabolism 34 (6), 836-856. e5, 2022 | 55 | 2022 |
| Transgenerational sterility of piwi mutants represents a dynamic form of adult reproductive diapause B Heestand, M Simon, S Frenk, D Titov, S Ahmed Cell reports 23 (1), 156-171, 2018 | 42 | 2018 |
| A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ... The EMBO Journal 41 (21), e110393, 2022 | 39 | 2022 |
| Caenorhabditis elegans POT-1 and POT-2 Repress Telomere Maintenance Pathways L Shtessel, MR Lowden, C Cheng, M Simon, K Wang, S Ahmed G3: Genes| Genomes| Genetics 3 (2), 305-313, 2013 | 34 | 2013 |
| Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ... Nature 572 (7767), E5-E5, 2019 | 25 | 2019 |
| LINE-1 derepression in senescent cells triggers interferon and inflammaging M De Cecco, T Ito, AP Petrashen, AE Elias, NJ Skvir, SW Criscione, ... Nature 566 (7742), 73, 2019 | 22 | 2019 |
| Accurate proteomewide measurement of methionine oxidation in aging mouse brains JQ Bettinger, M Simon, A Korotkov, KA Welle, JR Hryhorenko, A Seluanov, ... Journal of Proteome Research 21 (6), 1495-1509, 2022 | 12 | 2022 |
| Assessment of land cover changes in Lake Olbolosat region of the central Kenyan highlands using Landsat satellite imagery aided by indigenous knowledge M Zacharia, A Elias, K Jeremiah, M Simon, LO Olang Journal of Biodiversity Management Forestry 2, 2, 2013 | 12 | 2013 |
| The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing KK Billmyre, AL Doebley, M Spichal, B Heestand, T Belicard, ... PLoS Genetics 15 (3), e1008004, 2019 | 9 | 2019 |
| A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ... The EMBO Journal 42 (3), e113326, 2023 | 5 | 2023 |
| A hairy tale: SIRT 7 safeguards skin stem cells during aging M Simon, S Emmrich, A Seluanov, V Gorbunova The EMBO Journal 39 (18), e106294, 2020 | 4 | 2020 |
| cGAS deficient mice display premature aging associated with de-repression of LINE1 elements and inflammation JC Martinez, F Morandini, L Fitzgibbons, N Sieczkiewicz, SJ Bae, ... bioRxiv, 2024 | 1 | 2024 |