The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases H Altae-Tran, S Kannan, FE Demircioglu, R Oshiro, SP Nety, LJ McKay, ... Science 374 (6563), 57-65, 2021 | 279 | 2021 |
Compact RNA editors with small Cas13 proteins S Kannan, H Altae-Tran, X Jin, VJ Madigan, R Oshiro, KS Makarova, ... Nature biotechnology 40 (2), 194-197, 2022 | 141 | 2022 |
High-resolution structure of Cas13b and biochemical characterization of RNA targeting and cleavage IM Slaymaker, P Mesa, MJ Kellner, S Kannan, E Brignole, J Koob, ... Cell reports 26 (13), 3741-3751. e5, 2019 | 124 | 2019 |
Fanzor is a eukaryotic programmable RNA-guided endonuclease M Saito, P Xu, G Faure, S Maguire, S Kannan, H Altae-Tran, S Vo, ... Nature 620 (7974), 660-668, 2023 | 123 | 2023 |
Uncovering the functional diversity of rare CRISPR-Cas systems with deep terascale clustering H Altae-Tran, S Kannan, AJ Suberski, KS Mears, FE Demircioglu, ... Science 382 (6673), eadi1910, 2023 | 60 | 2023 |
Cryo-EM structure of the transposon-associated TnpB enzyme R Nakagawa, H Hirano, SN Omura, S Nety, S Kannan, H Altae-Tran, ... Nature 616 (7956), 390-397, 2023 | 56 | 2023 |
BorodinaI (2018) Glucose-Dependent Promoters for Dynamic Regulation of Metabolic Pathways J Maury, S Kannan, NB Jensen, FK Öberg, KR Kildegaard, J Forster, ... Synthetic Biology-Guided Metabolic Engineering 6, 63, 2020 | 44* | 2020 |
Glucose-dependent promoters for dynamic regulation of metabolic pathways J Maury, S Kannan, NB Jensen, FK Öberg, KR Kildegaard, J Forster, ... Frontiers in bioengineering and biotechnology 6, 63, 2018 | 44 | 2018 |
Diversity, evolution, and classification of the RNA-guided nucleases TnpB and Cas12 H Altae-Tran, SA Shmakov, KS Makarova, YI Wolf, S Kannan, F Zhang, ... Proceedings of the National Academy of Sciences 120 (48), e2308224120, 2023 | 32 | 2023 |
Structure of the IscB–ωRNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9 K Kato, S Okazaki, S Kannan, H Altae-Tran, F Esra Demircioglu, ... Nature Communications 13 (1), 6719, 2022 | 27 | 2022 |
Structure and engineering of the minimal type VI CRISPR-Cas13bt3 R Nakagawa, S Kannan, H Altae-Tran, SN Takeda, A Tomita, H Hirano, ... Molecular cell 82 (17), 3178-3192. e5, 2022 | 27 | 2022 |
Structure of the OMEGA nickase IsrB in complex with ωRNA and target DNA S Hirano, K Kappel, H Altae-Tran, G Faure, ME Wilkinson, S Kannan, ... Nature 610 (7932), 575-581, 2022 | 22 | 2022 |
The Transposon-Encoded Protein TnpB Processes Its Own mRNA into ωRNA for Guided Nuclease Activity SP Nety, H Altae-Tran, S Kannan, FE Demircioglu, G Faure, S Hirano, ... The CRISPR Journal 6 (3), 232-242, 2023 | 21 | 2023 |
Reconstructing dynamic promoter activity profiles from reporter gene data S Kannan, T Sams, J Maury, CT Workman ACS Synthetic Biology 7 (3), 832-841, 2018 | 10 | 2018 |
Final four landing sites for the InSight geophysical lander M Golombek, N Wigton, C Bloom, C Schwartz, S Kannan, D Kipp, ... 45th Annual Lunar and Planetary Science Conference, 1499, 2014 | 8 | 2014 |
The changing California coast: relationships between climatic variables and coastal vegetation succession WC Hsu, A Remar, E Williams, A McClure, S Kannan, R Steers, C Schmidt, ... ASPRS 2012 Annual Conference, Sacramento CA, 2012 | 8 | 2012 |
Therapeutic gene editing is here, can regulations keep up? S Kannan, D Najjar MIT Science Policy Review 1, 64-75, 2020 | 6 | 2020 |
Final four landing sites for the InSight geophysical lander (expanded abstract): 45th Lunar and Planetary Science M Golombek, N Warner, N Wigton, C Bloom, C Schwartz, S Kannan, ... Abstract, 2014 | 4 | 2014 |
Structural determinants of DNA cleavage by a CRISPR HNH-Cascade system S Hirano, H Altae-Tran, S Kannan, RK Macrae, F Zhang Molecular Cell 84 (16), 3154-3162. e5, 2024 | 2 | 2024 |
Modeling the Effects of Climate Change on Whitebark Pine Along the Pacific Crest Trail RS Anderson, A Nguyen, N Gill, S Kannan, N Patadia, M Meyer, ... AGU Fall Meeting Abstracts 2012, ED11A-0719, 2012 | 1 | 2012 |