Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template BD Sather, GS Romano Ibarra, K Sommer, G Curinga, M Hale, IF Khan, ... Science translational medicine 7 (307), 307ra156-307ra156, 2015 | 288 | 2015 |
Engineering HIV-resistant, anti-HIV chimeric antigen receptor T cells M Hale, T Mesojednik, GSR Ibarra, J Sahni, A Bernard, K Sommer, ... Molecular therapy 25 (3), 570-579, 2017 | 197 | 2017 |
TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin T Rehman, IM Thornell, AA Pezzulo, AL Thurman, GS Romano Ibarra, ... American Journal of Physiology-Cell Physiology 319 (2), C331-C344, 2020 | 38 | 2020 |
Lack of airway submucosal glands impairs respiratory host defenses LS Ostedgaard, MP Price, KM Whitworth, MH Abou Alaiwa, AJ Fischer, ... Elife 9, e59653, 2020 | 37 | 2020 |
Rapid profiling of protein kinase inhibitors by quantitative proteomics M Golkowski, JL Brigham, BGK Perera, GS Romano, DJ Maly, SE Ong Medchemcomm 5 (3), 363-369, 2014 | 27 | 2014 |
Efficient modification of the CCR5 locus in primary human T cells with megaTAL nuclease establishes HIV-1 resistance GSR Ibarra, B Paul, BD Sather, PM Younan, K Sommer, JP Kowalski, ... Molecular Therapy Nucleic Acids 5, 2016 | 22 | 2016 |
A single-cell atlas of large and small airways at birth in a porcine model of cystic fibrosis AL Thurman, X Li, R Villacreses, W Yu, H Gong, SE Mather, ... American journal of respiratory cell and molecular biology 66 (6), 612-622, 2022 | 16 | 2022 |
Efficient enrichment of gene-modified primary T cells via CCR5-targeted integration of mutant dihydrofolate reductase B Paul, GSR Ibarra, N Hubbard, T Einhaus, A Astrakhan, DJ Rawlings, ... Molecular Therapy Methods & Clinical Development 9, 347-357, 2018 | 14 | 2018 |
Detargeting lentiviral-mediated CFTR expression in airway basal cells using miR-106b SH Choi, RE Reeves, GS Romano Ibarra, TJ Lynch, WS Shahin, Z Feng, ... Genes 11 (10), 1169, 2020 | 5 | 2020 |
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template. Sci Transl Med. 2015; 7 (307): 307ra156 BD Sather, GS Romano Ibarra, K Sommer, G Curinga, M Hale, IF Khan | 5 | |
Airway epithelial cell subsets differentially contribute to CFTR-dependent chloride transport RGS Ibarra, IM Thornell, L Lei, AA Pezzulo, P Karp, LS Ostedgaard, ... Pediatric Pulmonology 54, S156-S156, 2019 | 2 | 2019 |
284. High-Efficiency Targeted Introduction of an Anti-CD19 CAR Into the CCR5 Locus in Primary Human T Cells M Hale, GSR Ibarra, IF Khan, J Sahni, AM Scharenberg, DJ Rawlings Molecular Therapy 23, S113-S114, 2015 | 2 | 2015 |
Topography-dependent gene expression and function of common cell archetypes in large and small porcine airways AA Pezzulo, AL Thurman, X Li, R Villacreses, W Yu, SE Mather, ... bioRxiv, 2021.03. 16.435690, 2021 | 1 | 2021 |
761. Targeted Killing of HIV Infected Cells Using CCR5-Disrupted Anti-HIV-CAR T Cells GSR Ibarra, M Hale, K Sommer, I Khan, J Sahni, C Peterson, HP Kiem, ... Molecular Therapy 24, S301, 2016 | 1 | 2016 |
452. MegaTAL Disruption of CCR5 To Protect Anti-HIV CAR+ Lymphocytes from HIV Infection TA Wagner, M Hale, G Romano, I Kahn, J Sahni, A Scharenberg, ... Molecular Therapy 23, S179-S180, 2015 | 1 | 2015 |
116. MegaTAL nucleases outperform TALENs in promoting homology-directed-gene modification in primary human T cells G Curinga, G Romano, B Sather, K Sommer, M Hale, I Khan, S Singh, ... Molecular Therapy 23, S48, 2015 | 1 | 2015 |
Contributions of MUC5B to Mucociliary Clearance Using A Genetically Modified Pig Model GS Romano Ibarra C109. EVEN BETTER THAN THE REAL THING: ADVANCED MODELS OF LUNG DISEASE …, 2023 | | 2023 |
IL-13 Induces Epigenetic Inflammatory Memory in a Subset of Airway Stem Cell Clones GC Necker, R Gannon, H Gong, A Thurman, L Tran, R Tudas, ... C13. CYTOKINES: CYTOKINES IN THE AIRWAYS, A4477-A4477, 2023 | | 2023 |
Role of Human Secretory Cells as Potential Airway Progenitor Cells During Re-Epithelialization GS Romano Ibarra, I Thornell, ND Gansamer, AA Pezzulo, DA Stoltz A98. EPITHELIAL-MESENCHYMAL BIOLOGY IN LUNG DEVELOPMENT AND REGENERATION …, 2022 | | 2022 |
Delivery and Tracking of CCR5-Disrupted, HIVCAR T Cells in SHIV-Infected, Non-Human Primates C Clough, M Hale, C Peterson, T Mesojednik, B Sands, MA O'Connor, ... MOLECULAR THERAPY 25 (5), 348-348, 2017 | | 2017 |