Human iPSC-derived neuronal models for in vitro neurotoxicity assessment AM Tukker, FMJ Wijnolts, A de Groot, RHS Westerink Neurotoxicology 67, 215-225, 2018 | 142 | 2018 |
Is the time right for in vitro neurotoxicity testing using human iPSC-derived neurons? AM Tukker, MW de Groot, FMJ Wijnolts, EEJ Kasteel, L Hondebrink, ... ALTEX-Alternatives to animal experimentation 33 (3), 261-271, 2016 | 91 | 2016 |
Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) acutely affect human α1β2γ2L GABAA receptor and spontaneous neuronal network function in vitro AM Tukker, LMS Bouwman, RGDM van Kleef, HS Hendriks, J Legler, ... Scientific reports 10 (1), 5311, 2020 | 66 | 2020 |
Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment AM Tukker, FMJ Wijnolts, A de Groot, RHS Westerink Toxicological Sciences 178 (1), 71-87, 2020 | 52 | 2020 |
Towards animal-free neurotoxicity screening: Applicability of hiPSC-derived neuronal models for in vitro seizure liability assessment AM Tukker, RGDM Van Kleef, FMJ Wijnolts, A De Groot, RHS Westerink ALTEX-Alternatives to animal experimentation 37 (1), 121-135, 2020 | 49 | 2020 |
Neuropharmacological characterization of the new psychoactive substance methoxetamine L Hondebrink, EEJ Kasteel, AM Tukker, FMJ Wijnolts, AHA Verboven, ... Neuropharmacology 123, 1-9, 2017 | 45 | 2017 |
Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1. 2-L1342P genetic variant Z Que, MI Olivero-Acosta, J Zhang, M Eaton, AM Tukker, X Chen, J Wu, ... Journal of Neuroscience 41 (49), 10194-10208, 2021 | 36 | 2021 |
The impact of environmental factors on monogenic Mendelian diseases AM Tukker, CD Royal, AB Bowman, KA McAllister Toxicological Sciences 181 (1), 3-12, 2021 | 28 | 2021 |
Novel test strategies for in vitro seizure liability assessment AM Tukker, RHS Westerink Expert Opinion on Drug Metabolism & Toxicology 17 (8), 923-936, 2021 | 22 | 2021 |
Single cell RNA sequencing detects persistent cell type-and methylmercury exposure paradigm-specific effects in a human cortical neurodevelopmental model MD Neely, S Xie, LM Prince, H Kim, AM Tukker, M Aschner, ... Food and Chemical Toxicology 154, 112288, 2021 | 18 | 2021 |
Solubility constraints on aquatic ecotoxicity testing of anionic surfactants J Hammer, AM Tukker, JF Postma, JJH Haftka, JLM Hermens, P De Voogt, ... Bulletin of environmental contamination and toxicology 101, 99-104, 2018 | 15 | 2018 |
In vitro techniques for assessing neurotoxicity using human iPSC-derived neuronal models AM Tukker, FMJ Wijnolts, A de Groot, RW Wubbolts, RHS Westerink Cell Culture Techniques, 17-35, 2019 | 8 | 2019 |
Mixture effects of tetrodotoxin (TTX) and drugs targeting voltage-gated sodium channels on spontaneous neuronal activity in vitro AM Tukker, MF Vrolijk, RGDM van Kleef, DTHM Sijm, RHS Westerink Toxicology Letters 373, 53-61, 2023 | 6 | 2023 |
Application of single cell gene expression technologies to neurotoxicology AM Tukker, AB Bowman Current Opinion in Toxicology 37, 100458, 2024 | 4 | 2024 |
The use of human iPSC-derived neuronal cultures for the study of persistent neurotoxic effects AM Tukker, AB Bowman Academic Press, 2024 | | 2024 |
Cellular and molecular insights into the mechanisms of latent and persistent methylmercury neurotoxicity AB BOWMAN, AM TUKKER, MD NEELY, J THIMMAPURAM, ... 日本毒性学会学術年会 第 49 回日本毒性学会学術年会, S33-2, 2022 | | 2022 |
Exciting Models. Exploring the Applicability of Human Neuronal Cell Models for In Vitro Neurotoxicity Screening and Seizure Liability Assessment AM Tukker Utrecht University, 2020 | | 2020 |