| The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor M Grell, E Douni, H Wajant, M Löhden, M Clauss, B Maxeiner, ... Cell 83 (5), 793-802, 1995 | 1816 | 1995 |
| On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease G Kollias, E Douni, G Kassiotis, D Kontoyiannis Immunological reviews 169 (1), 175-194, 1999 | 383 | 1999 |
| RANKL inhibition improves muscle strength and insulin sensitivity and restores bone mass N Bonnet, L Bourgoin, E Biver, E Douni, S Ferrari The Journal of clinical investigation 129 (8), 3214-3223, 2023 | 266 | 2023 |
| The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease G Kollias, E Douni, G Kassiotis, D Kontoyiannis Annals of the rheumatic diseases 58, I32-I39, 1999 | 257* | 1999 |
| In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis S Küsters, G Tiegs, L Alexopoulou, M Pasparakis, E Douni, G Künstle, ... European journal of immunology 27 (11), 2870-2875, 1997 | 235 | 1997 |
| Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity L Alexopoulou, K Kranidioti, S Xanthoulea, M Denis, A Kotanidou, ... European journal of immunology 36 (10), 2768-2780, 2006 | 172 | 2006 |
| A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin α, or the p55TNF-R E Douni, G Kollias The Journal of experimental medicine 188 (7), 1343-1352, 1998 | 161 | 1998 |
| Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis. E Douni, K Akassoglou, L Alexopoulou, S Georgopoulos, S Haralambous, ... Journal of inflammation 47 (1-2), 27-38, 1995 | 154 | 1995 |
| Tumor necrosis factor‐receptor 2 is up‐regulated on lamina propria T cells in Crohn's disease and promotes experimental colitis in vivo MH Holtmann, E Douni, M Schütz, G Zeller, J Mudter, HA Lehr, ... European journal of immunology 32 (11), 3142-3151, 2002 | 129 | 2002 |
| Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice K Akassoglou, E Douni, J Bauer, H Lassmann, G Kollias, L Probert Proceedings of the National Academy of Sciences 100 (2), 709-714, 2003 | 113 | 2003 |
| Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols E Douni, PP Sfikakis, S Haralambous, P Fernandes, G Kollias Arthritis Res Ther 6, 1-8, 2003 | 87 | 2003 |
| Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice V Rinotas, A Niti, R Dacquin, N Bonnet, M Stolina, CY Han, P Kostenuik, ... Journal of Bone and Mineral Research 29 (5), 1158-1169, 2014 | 80 | 2014 |
| Reporting guidelines, review of methodological standards, and challenges toward harmonization in bone marrow adiposity research. Report of the methodologies working group of … J Tratwal, R Labella, N Bravenboer, G Kerckhofs, E Douni, EL Scheller, ... Frontiers in endocrinology 11, 65, 2020 | 77 | 2020 |
| A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF E Douni, V Rinotas, E Makrinou, J Zwerina, JM Penninger, E Eliopoulos, ... Human molecular genetics 21 (4), 784-798, 2012 | 77 | 2012 |
| Tumour necrosis factors in immune regulation: everything that's interesting is… new! M Pasparakis, L Alexopoulou, E Douni, G Kollias Cytokine & growth factor reviews 7 (3), 223-229, 1996 | 71 | 1996 |
| Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL) G Melagraki, E Ntougkos, V Rinotas, C Papaneophytou, G Leonis, ... PLoS computational biology 13 (4), e1005372, 2017 | 57 | 2017 |
| A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice F Ioakeimidis, C Ott, V Kozjak-Pavlovic, F Violitzi, V Rinotas, E Makrinou, ... PloS one 9 (8), e104237, 2014 | 57 | 2014 |
| The Role of TNF/TNFR in Organ-Specific and Systemic Autoimmunity: Implications for the Design of OptimizedAnti-TNF'Therapies G Kollias, D Kontoyiannis, E Douni, G Kassiotis Current Directions in Autoimmunity 5, 30-50, 2002 | 55 | 2002 |
| New insights for RANKL as a proinflammatory modulator in modeled inflammatory arthritis M Papadaki, V Rinotas, F Violitzi, T Thireou, G Panayotou, M Samiotaki, ... Frontiers in immunology 10, 97, 2019 | 54 | 2019 |
| Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice L Probert, K Akassoglou, L Alexopoulou, E Douni, S Haralambous, S Hill, ... Journal of Leucocyte Biology 59 (4), 518-525, 1996 | 54 | 1996 |
