The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids AJ Brown, SM Goldsworthy, AA Barnes, MM Eilert, L Tcheang, D Daniels, ... Journal of Biological Chemistry 278 (13), 11312-11319, 2003 | 2593 | 2003 |
Reducing safety-related drug attrition: the use of in vitro pharmacological profiling J Bowes, AJ Brown, J Hamon, W Jarolimek, A Sridhar, G Waldron, ... Nature reviews Drug discovery 11 (12), 909-922, 2012 | 786 | 2012 |
Molecular identification of high and low affinity receptors for nicotinic acid A Wise, SM Foord, NJ Fraser, AA Barnes, N Elshourbagy, M Eilert, ... Journal of Biological Chemistry 278 (11), 9869-9874, 2003 | 662 | 2003 |
Novel cannabinoid receptors AJ Brown British journal of pharmacology 152 (5), 567-575, 2007 | 592 | 2007 |
The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain PC Staton, JP Hatcher, DJ Walker, AD Morrison, EM Shapland, ... Pain 139 (1), 225-236, 2008 | 342 | 2008 |
The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects DG Johns, DJ Behm, DJ Walker, Z Ao, EM Shapland, DA Daniels, ... British journal of pharmacology 152 (5), 825-831, 2007 | 302 | 2007 |
GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils NAB Balenga, E Aflaki, J Kargl, W Platzer, R Schröder, S Blättermann, ... Cell research 21 (10), 1452-1469, 2011 | 238 | 2011 |
Mating in mushrooms: increasing the chances but prolonging the affair AJ Brown, LA Casselton TRENDS in Genetics 17 (7), 393-400, 2001 | 238 | 2001 |
Functional coupling of mammalian receptors to the yeast mating pathway using novel yeast/mammalian G protein α‐subunit chimeras AJ Brown, SL Dyos, MS Whiteway, JHM White, MAEA Watson, ... Yeast 16 (1), 11-22, 2000 | 226 | 2000 |
Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein–coupled receptors C Southern, JM Cook, Z Neetoo-Isseljee, DL Taylor, CA Kettleborough, ... Journal of Biomolecular Screening 18 (5), 599-609, 2013 | 225 | 2013 |
A family of fatty acid binding receptors AJ Brown, S Jupe, CP Briscoe DNA and cell biology 24 (1), 54-61, 2005 | 182 | 2005 |
The G-protein-coupled receptor 40 family (GPR40–GPR43) and its role in nutrient sensing DK Covington, CA Briscoe, AJ Brown, CK Jayawickreme Biochemical Society Transactions 34 (5), 770-773, 2006 | 181 | 2006 |
Minireview: recent developments in the physiology and pathology of the lysophosphatidylinositol-sensitive receptor GPR55 CM Henstridge, NAB Balenga, J Kargl, C Andradas, AJ Brown, A Irving, ... Molecular endocrinology 25 (11), 1835-1848, 2011 | 180 | 2011 |
A constitutively active G‐protein‐coupled receptor causes mating self‐compatibility in the mushroom Coprinus NS Olesnicky, AJ Brown, SJ Dowell, LA Casselton The EMBO Journal, 1999 | 136 | 1999 |
Yeast assays for G-protein-coupled receptors SJ Dowell, AJ Brown receptors and channels 8 (5-6), 343-352, 2002 | 132 | 2002 |
Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short … LA Stoddart, NJ Smith, L Jenkins, AJ Brown, G Milligan Journal of Biological Chemistry 283 (47), 32913-32924, 2008 | 126 | 2008 |
The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55 J Kargl, N Balenga, GP Parzmair, AJ Brown, A Heinemann, M Waldhoer Journal of Biological Chemistry 287 (53), 44234-44248, 2012 | 112 | 2012 |
Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5′-O-(3-[35S] thio) triphosphate binding studies reflects … LA Stoddart, AJ Brown, G Milligan Molecular pharmacology 71 (4), 994-1005, 2007 | 101 | 2007 |
A selective antagonist reveals a potential role of G protein–coupled receptor 55 in platelet and endothelial cell function J Kargl, AJ Brown, L Andersen, G Dorn, R Schicho, M Waldhoer, ... The Journal of pharmacology and experimental therapeutics 346 (1), 54-66, 2013 | 100 | 2013 |
The origin of multiple B mating specificities in Coprinus cinereus M Riquelme, MP Challen, LA Casselton, AJ Brown Genetics 170 (3), 1105-1119, 2005 | 95 | 2005 |