Human polymorphism at microRNAs and microRNA target sites MA Saunders, H Liang, WH Li Proceedings of the National Academy of Sciences 104 (9), 3300-3305, 2007 | 795 | 2007 |
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ... The Lancet Oncology 17 (10), 1386-1395, 2016 | 482 | 2016 |
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function SA Melo, S Ropero, C Moutinho, LA Aaltonen, H Yamamoto, GA Calin, ... Nature genetics 41 (3), 365-370, 2009 | 474 | 2009 |
A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells SA Melo, C Moutinho, S Ropero, GA Calin, S Rossi, R Spizzo, ... Cancer cell 18 (4), 303-315, 2010 | 461 | 2010 |
Benchmarking single-cell RNA-sequencing protocols for cell atlas projects E Mereu, A Lafzi, C Moutinho, C Ziegenhain, DJ McCarthy, ... Nature biotechnology 38 (6), 747-755, 2020 | 429 | 2020 |
Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis V Davalos, C Moutinho, A Villanueva, R Boque, P Silva, F Carneiro, ... Oncogene 31 (16), 2062-2074, 2012 | 411 | 2012 |
Tumor-related molecular mechanisms of oxaliplatin resistance E Martinez-Balibrea, A Martínez-Cardús, A Ginés, V Ruiz de Porras, ... Molecular cancer therapeutics 14 (8), 1767-1776, 2015 | 326 | 2015 |
KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression C Oliveira, S Velho, C Moutinho, A Ferreira, A Preto, E Domingo, ... Oncogene 26 (1), 158-163, 2007 | 293 | 2007 |
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing S Melo, A Villanueva, C Moutinho, V Davalos, R Spizzo, C Ivan, S Rossi, ... Proceedings of the National Academy of Sciences 108 (11), 4394-4399, 2011 | 288 | 2011 |
BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis? S Velho, C Moutinho, L Cirnes, C Albuquerque, R Hamelin, F Schmitt, ... BMC cancer 8, 1-6, 2008 | 265 | 2008 |
Head-to-head antisense transcription and R-loop formation promotes transcriptional activation R Boque-Sastre, M Soler, C Oliveira-Mateos, A Portela, C Moutinho, ... Proceedings of the National Academy of Sciences 112 (18), 5785-5790, 2015 | 259 | 2015 |
BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes E Domingo, RC Niessen, C Oliveira, P Alhopuro, C Moutinho, E Espín, ... Oncogene 24 (24), 3995-3998, 2005 | 223 | 2005 |
Mechanisms of therapy resistance in patient-derived xenograft models of BRCA1-deficient breast cancer P Ter Brugge, P Kristel, E Van Der Burg, U Boon, M De Maaker, E Lips, ... Journal of the National Cancer Institute 108 (11), djw148, 2016 | 218 | 2016 |
Tutorial: guidelines for the experimental design of single-cell RNA sequencing studies A Lafzi, C Moutinho, S Picelli, H Heyn Nature protocols 13 (12), 2742-2757, 2018 | 212 | 2018 |
Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis M Rodriguez-Paredes, A Martinez de Paz, L Simo-Riudalbas, S Sayols, ... Oncogene 33 (21), 2807-2813, 2014 | 182 | 2014 |
Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer A Diaz-Lagares, AB Crujeiras, P Lopez-Serra, M Soler, F Setien, A Goyal, ... Proceedings of the National Academy of Sciences 113 (47), E7535-E7544, 2016 | 172 | 2016 |
Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs V Nogales, WC Reinhold, S Varma, A Martinez-Cardus, C Moutinho, ... Oncotarget 7 (3), 3084, 2015 | 150 | 2015 |
Three-dimensional genomic structure and cohesin occupancy correlate with transcriptional activity during spermatogenesis C Vara, A Paytuví-Gallart, Y Cuartero, F Le Dily, F Garcia, J Salvà-Castro, ... Cell reports 28 (2), 352-367. e9, 2019 | 147 | 2019 |
A single-cell tumor immune atlas for precision oncology P Nieto, M Elosua-Bayes, JL Trincado, D Marchese, R Massoni-Badosa, ... Genome research 31 (10), 1913-1926, 2021 | 144 | 2021 |
MicroRNAs and epigenetics C Moutinho, M Esteller Advances in cancer research 135, 189-220, 2017 | 137 | 2017 |