| PI3K/AKT signaling pathway and cancer: an updated review M Martini, MC De Santis, L Braccini, F Gulluni, E Hirsch Annals of medicine 46 (6), 372-383, 2014 | 1260 | 2014 |
| Phosphoinositide 3-kinase gamma inhibition protects from anthracycline cardiotoxicity and reduces tumor growth M Li, V Sala, MC De Santis, J Cimino, P Cappello, N Pianca, A Di Bona, ... Circulation 138 (7), 696-711, 2018 | 193 | 2018 |
| Class II PI3K functions in cell biology and disease F Gulluni, MC De Santis, JP Margaria, M Martini, E Hirsch Trends in cell biology 29 (4), 339-359, 2019 | 141 | 2019 |
| Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes CC Campa, JP Margaria, A Derle, M Del Giudice, MC De Santis, ... Nature chemical biology 14 (8), 801-810, 2018 | 108 | 2018 |
| Targeting PI3K signaling in cancer: Challenges and advances MC De Santis, F Gulluni, CC Campa, M Martini, E Hirsch Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1871 (2), 361-366, 2019 | 97 | 2019 |
| Mitotic spindle assembly and genomic stability in breast cancer require PI3K-C2α scaffolding function F Gulluni, M Martini, MC De Santis, CC Campa, A Ghigo, JP Margaria, ... Cancer cell 32 (4), 444-459. e7, 2017 | 90 | 2017 |
| PI (3, 4) P2 signaling in cancer and metabolism L Gozzelino, MC De Santis, F Gulluni, E Hirsch, M Martini Frontiers in oncology 10, 360, 2020 | 70 | 2020 |
| Signaling pathways regulating redox balance in cancer metabolism MC De Santis, PE Porporato, M Martini, A Morandi Frontiers in oncology 8, 126, 2018 | 70 | 2018 |
| The PI3K/Akt/mTOR pathway in polycystic kidney disease: A complex interaction with polycystins and primary cilium JP Margaria, CC Campa, MC De Santis, E Hirsch, I Franco Cellular signalling 66, 109468, 2020 | 63 | 2020 |
| Phosphoinositide 3-kinase-C2α regulates polycystin-2 ciliary entry and protects against kidney cyst formation I Franco, JP Margaria, MC De Santis, A Ranghino, D Monteyne, ... Journal of the American Society of Nephrology 27 (4), 1135-1144, 2016 | 56 | 2016 |
| A novel multiplex qRT-PCR assay to detect SARS-CoV-2 infection: high sensitivity and increased testing capacity S Petrillo, G Carrà, P Bottino, E Zanotto, MC De Santis, JP Margaria, ... Microorganisms 8 (7), 1064, 2020 | 48 | 2020 |
| PI (3, 4) P2-mediated cytokinetic abscission prevents early senescence and cataract formation F Gulluni, L Prever, H Li, P Krafcikova, I Corrado, WT Lo, JP Margaria, ... Science 374 (6573), eabk0410, 2021 | 44 | 2021 |
| PI3K signaling in tissue hyper-proliferation: from overgrowth syndromes to kidney cysts MC De Santis, V Sala, M Martini, GB Ferrero, E Hirsch Cancers 9 (4), 30, 2017 | 44 | 2017 |
| The role of metabolic adaptation to nutrient stress in pancreatic cancer A Derle, MC De Santis, L Gozzelino, E Ratto, M Martini Cell Stress 2 (12), 332, 2018 | 28 | 2018 |
| Structural basis of phosphatidylinositol 3-kinase C2α function WT Lo, Y Zhang, O Vadas, Y Roske, F Gulluni, MC De Santis, AV Zagar, ... Nature structural & molecular biology 29 (3), 218-228, 2022 | 26 | 2022 |
| Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer MC De Santis, L Gozzelino, JP Margaria, A Costamagna, E Ratto, ... Gut 72 (2), 360-371, 2023 | 18 | 2023 |
| How PI3K-derived lipids control cell division CC Campa, M Martini, MC De Santis, E Hirsch Frontiers in cell and developmental biology 3, 61, 2015 | 18 | 2015 |
| Exploiting pancreatic cancer metabolism: challenges and opportunities MC De Santis, B Bockorny, E Hirsch, P Cappello, M Martini Trends in Molecular Medicine, 2024 | 16 | 2024 |
| Phosphoinositide conversion inactivates R‐RAS and drives metastases in breast cancer H Li, L Prever, MY Hsu, WT Lo, JP Margaria, MC De Santis, C Zanini, ... Advanced Science 9 (9), 2103249, 2022 | 16 | 2022 |
| Novel Lymphocyte-Independent Antitumor Activity by PD-1 Blocking Antibody against PD-1+ Chemoresistant Lung Cancer Cells R Rotolo, V Leuci, C Donini, F Galvagno, A Massa, MC De Santis, ... Clinical Cancer Research 29 (3), 621-634, 2023 | 8 | 2023 |
