Ultrasound-mediated disruption of the blood tumor barrier for improved therapeutic delivery TA Arsiwala, SA Sprowls, KE Blethen, CE Adkins, PA Saralkar, ... Neoplasia 23 (7), 676-691, 2021 | 44 | 2021 |
Effects of whole-brain radiation therapy on the blood–brain barrier in immunocompetent and immunocompromised mouse models KE Blethen, SA Sprowls, TA Arsiwala, CP Wolford, DM Panchal, ... Radiation Oncology 18 (1), 22, 2023 | 20 | 2023 |
Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases KE Blethen, TA Arsiwala, RA Fladeland, SA Sprowls, DM Panchal, ... Neuro-Oncology Advances 3 (Supplement_5), v133-v143, 2021 | 18 | 2021 |
Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model TA Arsiwala, SA Sprowls, KE Blethen, RA Fladeland, CP Wolford, ... Fluids and Barriers of the CNS 19 (1), 72, 2022 | 16 | 2022 |
Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy TA Arsiwala, KE Blethen, CP Wolford, DM Panchal, SA Sprowls, ... Frontiers in Oncology 13, 1104594, 2023 | 8 | 2023 |
Prenatal Cadmium Exposure Alters Proliferation in Mouse CD4+ T Cells via LncRNA Snhg7 JL McCall, ME Varney, E Rice, SA Dziadowicz, C Hall, KE Blethen, G Hu, ... Frontiers in Immunology 12, 720635, 2022 | 8 | 2022 |
Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo Z Liu, N Shah, KL Marshall, SA Sprowls, P Saralkar, A Mohammad, ... Archives of toxicology 95 (11), 3575-3587, 2021 | 8 | 2021 |
Prenatal cadmium exposure does not induce greater incidence or earlier onset of autoimmunity in the offspring JL McCall, HC Blair, KE Blethen, C Hall, M Elliott, JB Barnett Plos one 16 (9), e0249442, 2021 | 6 | 2021 |
A Review of Mathematics Determining Solute Uptake at the Blood–Brain Barrier in Normal and Pathological Conditions SA Sprowls, P Saralkar, T Arsiwala, CE Adkins, KE Blethen, VJ Pizzuti, ... Pharmaceutics 13 (5), 756, 2021 | 3 | 2021 |
BSBM-11 Combining Immunotherapy and Whole-Brain Radiation Therapy in a Novel Syngeneic Lung Cancer Brain Metastasis Preclinical Model: Does Timing of Administration Matter? K Blethen, S Sprowls, T Arsiwala, C Wolford, D Panchal, R Fladeland, ... Neuro-Oncology Advances 5 (Suppl 3), iii2, 2023 | 1 | 2023 |
A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma M Khasraw, K Singh, M Foster, M Violette, A Corcoran, K Hotchkiss, ... | | 2025 |
Focused ultrasound as an emerging therapy for neuropsychiatric disease: Historical perspectives and a review of current clinical data DN de Souza, A Seas, K Blethen, J Feigal, BR Shah, GA Grant, ... Psychiatry and Clinical Neurosciences, 2025 | | 2025 |
Single Exposure to Low-Intensity Focused Ultrasound Causes Biphasic Opening of the Blood-Brain Barrier Through Secondary Mechanisms TA Arsiwala, KE Blethen, CP Wolford, GL Pecar, DM Panchal, ... Pharmaceutics 17 (1), 75, 2025 | | 2025 |
Abstract A020: Liposomal topotecan with low-intensity focused ultrasound utilization to improve drug penetration with brain parenchyma in pediatric brain tumors A Mangoli, S Kim, K Blethen, A Everhart, S Nikiforov, G Grant, L Avigliano Molecular Cancer Therapeutics 23 (12_Supplement), A020-A020, 2024 | | 2024 |
A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma K Singh, MW Foster, MJ Violette, AM Corcoran, KM Hotchkiss, CO Railton, ... medRxiv, 2024.06. 19.24309192, 2024 | | 2024 |
Coordination of anti-CTLA-4 with whole-brain radiation therapy decreases tumor burden during treatment in a novel syngeneic model of lung cancer brain metastasis KE Blethen, CP Wolford, GL Pecar, TA Arsiwala, E Adjeroh, LP Dykstra, ... Cancer Immunology, Immunotherapy 73 (1), 20, 2024 | | 2024 |
BSBM-10 CHARACTERIZATION OF A RADIATION-RESISTANT MODEL OF LUNG CANCER BRAIN METASTASIS C Wolford, K Blethen, T Arsiwala, G Pecar, R Fladeland, D Panchal, ... Neuro-Oncology Advances 5 (Suppl 3), iii2, 2023 | | 2023 |
Right Treatment Wrong Time: Immunotherapy Administration Post-Radiotherapy Decreases Tumor Burden in a Preclinical Model of Brain Metastasis KE Blethen West Virginia University, 2023 | | 2023 |
Focused ultrasound induced blood-tumor barrier permeability of combinatorial chemotherapy TA Arsiwala, KE Blethen, SA Sprowls, RA Fladeland, B Keilkowski, ... Cancer Research 82 (12_Supplement), 3461-3461, 2022 | | 2022 |
Single exposure to low-intensity focused ultrasound causes biphasic opening of the blood-brain barrier on the sonicated and contralateral treated regions. TA Arsiwala, KE Blethen, CP Wolford, DM Panchal, BN Kielkowski, ... Exploiting modulation of the Blood-Brain and Blood-Tumor Barrier …, 2022 | | 2022 |