| The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures BA Kaufman, N Durisic, JM Mativetsky, S Costantino, MA Hancock, ... Molecular biology of the cell 18 (9), 3225-3236, 2007 | 473 | 2007 |
| Structural basis for allosteric PARP-1 retention on DNA breaks L Zandarashvili, MF Langelier, UK Velagapudi, MA Hancock, JD Steffen, ... Science 368 (6486), eaax6367, 2020 | 296 | 2020 |
| Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination G Veit, A Roldan, MA Hancock, DF Da Fonte, H Xu, M Hussein, S Frenkiel, ... JCI insight 5 (18), e139983, 2020 | 224 | 2020 |
| Isolation and characterization of α-enolase, a novel fibronectin-binding protein from Streptococcus suis M Esgleas, Y Li, MA Hancock, J Harel, JD Dubreuil, M Gottschalk Microbiology 154 (9), 2668-2679, 2008 | 204 | 2008 |
| Inhibition of plasminogen activation by lipoprotein (a): critical domains in apolipoprotein (a) and mechanism of inhibition on fibrin and degraded fibrin surfaces MA Hancock, MB Boffa, SM Marcovina, ME Nesheim, ML Koschinsky Journal of Biological Chemistry 278 (26), 23260-23269, 2003 | 190 | 2003 |
| Development of DNA nanostructures for high-affinity binding to human serum albumin A Lacroix, TGW Edwardson, MA Hancock, MD Dore, HF Sleiman Journal of the American Chemical Society 139 (21), 7355-7362, 2017 | 161 | 2017 |
| Structure-guided combination therapy to potently improve the function of mutant CFTRs G Veit, H Xu, E Dreano, RG Avramescu, M Bagdany, LK Beitel, A Roldan, ... Nature medicine 24 (11), 1732-1742, 2018 | 140 | 2018 |
| Apolipoprotein (a) enhances platelet responses to the thrombin receptor–activating peptide SFLLRN ML Rand, W Sangrar, MA Hancock, DM Taylor, SM Marcovina, ... Arteriosclerosis, thrombosis, and vascular biology 18 (9), 1393-1399, 1998 | 99 | 1998 |
| Defensin promotes the binding of lipoprotein (a) to vascular matrix K Bdeir, W Cane, G Canziani, I Chaiken, J Weisel, ML Koschinsky, ... Blood, The Journal of the American Society of Hematology 94 (6), 2007-2019, 1999 | 98 | 1999 |
| An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor PM LeBlanc, TA Doggett, J Choi, MA Hancock, Y Durocher, F Frank, ... Journal of Biological Chemistry 289 (11), 7777-7786, 2014 | 84 | 2014 |
| Interactions between TonB from Escherichia coli and the periplasmic protein FhuD DM Carter, IR Miousse, JN Gagnon, E Martinez, A Clements, J Lee, ... Journal of biological chemistry 281 (46), 35413-35424, 2006 | 75 | 2006 |
| Anti-myelin antibodies modulate clinical expression of childhood multiple sclerosis KC O'Connor, C Lopez-Amaya, D Gagne, L Lovato, NH Moore-Odom, ... Journal of neuroimmunology 223 (1-2), 92-99, 2010 | 74 | 2010 |
| The solution phase interaction between apolipoprotein (a) and plasminogen inhibits the binding of plasminogen to a plasmin-modified fibrinogen surface W Sangrar, BR Gabel, MB Boffa, JB Walker, MA Hancock, SM Marcovina, ... Biochemistry 36 (34), 10353-10363, 1997 | 72 | 1997 |
| Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression F Liebsch, L Kulic, C Teunissen, A Shobo, I Ulku, V Engelschalt, ... Nature communications 10 (1), 2240, 2019 | 64 | 2019 |
| Interaction between MMACHC and MMADHC, two human proteins participating in intracellular vitamin B12 metabolism M Plesa, J Kim, SG Paquette, H Gagnon, C Ng-Thow-Hing, BF Gibbs, ... Molecular genetics and metabolism 102 (2), 139-148, 2011 | 58 | 2011 |
| The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity M Wieczorek, J Tcherkezian, C Bernier, AE Prota, S Chaaban, Y Rolland, ... Science translational medicine 8 (365), 365ra159-365ra159, 2016 | 54 | 2016 |
| Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4 JC Deme, MA Hancock, X Xia, CA Shintre, M Plesa, JC Kim, ... Molecular membrane biology 31 (7-8), 250-261, 2014 | 51 | 2014 |
| Structural analysis and inhibition of TraE from the pKM101 type IV secretion system B Casu, J Smart, MA Hancock, M Smith, J Sygusch, C Baron Journal of Biological Chemistry 291 (45), 23817-23829, 2016 | 50 | 2016 |
| TonB Interacts with BtuF, the Escherichia coli Periplasmic Binding Protein for Cyanocobalamin KJ James, MA Hancock, JN Gagnon, JW Coulton Biochemistry 48 (39), 9212-9220, 2009 | 48 | 2009 |
| Stimulation of vascular smooth muscle cell proliferation and migration by apolipoprotein (a) is dependent on inhibition of transforming growth factor-β activation and on the … CH O'Neil, MB Boffa, MA Hancock, JG Pickering, ML Koschinsky Journal of Biological Chemistry 279 (53), 55187-55195, 2004 | 47 | 2004 |
