| Mechanisms and functions of spatial protein quality control EM Sontag, RS Samant, J Frydman Annual review of biochemistry 86 (1), 97-122, 2017 | 293 | 2017 |
| Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control RS Samant, CM Livingston, EM Sontag, J Frydman Nature 563 (7731), 407-411, 2018 | 180 | 2018 |
| ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system S Polier, RS Samant, PA Clarke, P Workman, C Prodromou, LH Pearl Nature chemical biology 9 (5), 307-312, 2013 | 172 | 2013 |
| A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease T Dale, PA Clarke, C Esdar, D Waalboer, O Adeniji-Popoola, ... Nature chemical biology 11 (12), 973, 2015 | 138 | 2015 |
| Alternative systems for misfolded protein clearance: life beyond the proteasome HE Johnston, RS Samant The FEBS journal 288 (15), 4464-4487, 2021 | 80 | 2021 |
| E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cells RS Samant, PA Clarke, P Workman Proceedings of the National Academy of Sciences 111 (18), 6834-6839, 2014 | 69 | 2014 |
| Solvent precipitation SP3 (SP4) enhances recovery for proteomics sample preparation without magnetic beads HE Johnston, K Yadav, JM Kirkpatrick, GS Biggs, D Oxley, HB Kramer, ... Analytical chemistry 94 (29), 10320-10328, 2022 | 60 | 2022 |
| The expanding proteome of the molecular chaperone HSP90 RS Samant, PA Clarke, P Workman Cell cycle 11 (7), 1301-1308, 2012 | 40 | 2012 |
| Native mass spectrometry analyses of chaperonin complex TRiC/CCT reveal subunit N-terminal processing and re-association patterns MP Collier, KB Moreira, KH Li, YC Chen, D Itzhak, R Samant, A Leitner, ... Scientific Reports 11 (1), 13084, 2021 | 16 | 2021 |
| Choose your protein partners RS Samant, P Workman Nature 490 (7420), 351-352, 2012 | 11 | 2012 |
| Methods for measuring misfolded protein clearance in the budding yeast Saccharomyces cerevisiae RS Samant, J Frydman Methods in enzymology 619, 27-45, 2019 | 10 | 2019 |
| A hierarchical assembly pathway directs the unique subunit arrangement of TRiC/CCT KB Moreira, MP Collier, A Leitner, KH Li, ILS Lachapel, F McCarthy, ... Molecular cell 83 (17), 3123-3139. e8, 2023 | 7 | 2023 |
| Dosage compensation plans: protein aggregation provides additional insurance against aneuploidy RS Samant, VB Masto, J Frydman Genes & Development 33 (15-16), 1027-1030, 2019 | 6 | 2019 |
| Native size-exclusion chromatography–based mass spectrometry reveals new components of the early heat shock protein 90 inhibition response among limited global changes RS Samant, S Batista, M Larance, B Ozer, CI Milton, I Bludau, E Wu, ... Molecular & Cellular Proteomics 22 (2), 2023 | 3 | 2023 |
| Ubiquitylomics: An Emerging Approach for Profiling Protein Ubiquitylation in Skeletal Muscle SO Lord, HE Johnston, RS Samant, YC Lai Journal of cachexia, sarcopenia and muscle 15 (6), 2281-2294, 2024 | 2 | 2024 |
| Discovery of preclinical development candidate inhibitors of the mediator complex-associated kinases CDK8 and CDK19 and evaluation of their therapeutic potential P Clarke, C Esdar, A Mallinger, K Schiemann, D Waalboer, S Crumpler, ... Cancer Research 76 (14_Supplement), 3025-3025, 2016 | 2 | 2016 |
| Native size exclusion chromatography-based mass spectrometry (SEC-MS) identifies novel components of the Heat Shock Protein 90-dependent proteome RS Samant, S Batista, M Larance, B Ozer, CI Milton, I Bludau, L Biggins, ... BioRxiv, 2022.05. 23.492985, 2022 | 1 | 2022 |
| Introduction: Molecular Chaperones and Protein Quality Control D Balchin, MA Rangel, RS Samant | | 2023 |
| INTERPLAY BETWEEN LOSS OF PROTEOSTASIS AND CELLULAR SENESCENCE: A SPOTLIGHT ON MISFOLDED PROTEIN QUALITY CONTROL R Samant Innovation in Aging 6 (Suppl 1), 424, 2022 | | 2022 |
| Dysregulated proteostasis: mechanisms and links to aging Y Al-Muftia, S Cranwella, RS Samant Molecular, Cellular, and Metabolic Fundamentals of Human Aging, 55, 2022 | | 2022 |