| Genome-scale CRISPR-Cas9 knockout screening in human cells O Shalem, NE Sanjana, E Hartenian, X Shi, DA Scott, TS Mikkelsen, ... Science 343 (6166), 84-87, 2014 | 5891 | 2014 |
| Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation JG Doench, E Hartenian, DB Graham, Z Tothova, M Hegde, I Smith, ... Nature biotechnology 32 (12), 1262-1267, 2014 | 1870 | 2014 |
| The molecular virology of coronaviruses E Hartenian, D Nandakumar, A Lari, M Ly, JM Tucker, BA Glaunsinger Journal of Biological Chemistry 295 (37), 12910-12934, 2020 | 595 | 2020 |
| Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens FJ Najm, C Strand, KF Donovan, M Hegde, KR Sanson, EW Vaimberg, ... Nature biotechnology 36 (2), 179-189, 2018 | 308 | 2018 |
| The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion JL Tenthorey, N Haloupek, JR López-Blanco, P Grob, E Adamson, ... Science 358 (6365), 888-893, 2017 | 186 | 2017 |
| Functional genomics using CRISPR-Cas systems, compositions, methods, screens and applications thereof F Zhang, O Shalem, NE Sanjana, J Doench, D Root, ENB Hartenian US Patent 10,781,444, 2020 | 164 | 2020 |
| Structural basis of NINJ1-mediated plasma membrane rupture in cell death M Degen, JC Santos, K Pluhackova, G Cebrero, S Ramos, G Jankevicius, ... Nature 618 (7967), 1065-1071, 2023 | 128 | 2023 |
| Genetic screens and functional genomics using CRISPR/Cas9 technology E Hartenian, JG Doench The FEBS journal 282 (8), 1383-1393, 2015 | 127 | 2015 |
| Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription S Gilbertson, JD Federspiel, E Hartenian, IM Cristea, B Glaunsinger elife 7, e37663, 2018 | 109 | 2018 |
| The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression AS Mendez, M Ly, AM González-Sánchez, E Hartenian, NT Ingolia, ... Cell Reports 37 (3), 2021 | 97 | 2021 |
| Genetic and proteomic interrogation of lower confidence candidate genes reveals signaling networks in β-catenin-active cancers J Rosenbluh, J Mercer, Y Shrestha, R Oliver, P Tamayo, JG Doench, ... Cell systems 3 (3), 302-316. e4, 2016 | 77 | 2016 |
| Feedback to the central dogma: cytoplasmic mRNA decay and transcription are interdependent processes E Hartenian, BA Glaunsinger Critical reviews in biochemistry and molecular biology 54 (4), 385-398, 2019 | 56 | 2019 |
| NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis S Ramos, E Hartenian, JC Santos, P Walch, P Broz The EMBO journal 43 (7), 1164-1186, 2024 | 38 | 2024 |
| Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis C Duncan-Lewis, E Hartenian, V King, BA Glaunsinger Elife 10, e58342, 2021 | 24 | 2021 |
| RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters E Hartenian, S Gilbertson, JD Federspiel, IM Cristea, BA Glaunsinger PLoS pathogens 16 (2), e1008269, 2020 | 21 | 2020 |
| Functional genomics using crispr-cas systems, compositions, methods, screens and applications thereof F Zhang, O Shalem, NE Sanjana, J Doench, D Root, ENB Hartenian US Patent App. 17/027,151, 2021 | 17 | 2021 |
| DNA processing by the Kaposi's sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production E Hartenian, AS Mendez, AL Didychuk, S Khosla, BA Glaunsinger Nucleic Acids Research 51 (1), 182-197, 2023 | 8 | 2023 |
| Fine-tuning phosphatidic acid production for optimal plant stress responses Q Gong, S Yao, X Wang, G Li Trends in Biochemical Sciences, 2024 | 5* | 2024 |
| Programmed cell death: NINJ1 and mechanisms of plasma membrane rupture S Ramos, E Hartenian, P Broz Trends in Biochemical Sciences 49 (8), 717-728, 2024 | 4 | 2024 |
| Herpesvirus infection reduces Pol II occupancy of host promoters but spares viral promoters EN Hartenian, BA Glaunsinger | 3 | 2019 |
