| Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors SA Ali, SM Awad, AM Said, S Mahgoub, H Taha, NM Ahmed Journal of enzyme inhibition and medicinal chemistry 35 (1), 847-863, 2020 | 68 | 2020 |
| Design, synthesis, molecular modelling, and biological evaluation of novel substituted pyrimidine derivatives as potential anticancer agents for hepatocellular carcinoma NM Ahmed, M Youns, MK Soltan, AM Said Journal of enzyme inhibition and medicinal chemistry 34 (1), 1110-1120, 2019 | 61 | 2019 |
| Discovery and characterization of potent dual P-glycoprotein and CYP3A4 inhibitors: design, synthesis, cryo-EM analysis, and biological evaluations S Urgaonkar, K Nosol, AM Said, NN Nasief, Y Bu, KP Locher, JYN Lau, ... Journal of Medicinal Chemistry 65 (1), 191-216, 2021 | 55 | 2021 |
| Design, synthesis, molecular modeling and antitumor evaluation of novel indolyl-pyrimidine derivatives with EGFR inhibitory activity NM Ahmed, MM Youns, MK Soltan, AM Said Molecules 26 (7), 1838, 2021 | 38 | 2021 |
| Design, synthesis, molecular modeling, and biological evaluation of novel thiouracil derivatives as potential antithyroid agents SM Awad, YM Zohny, SA Ali, S Mahgoub, AM Said Molecules 23 (11), 2913, 2018 | 32 | 2018 |
| Polyphenolic Profile of Callistemon viminalis Aerial Parts: Antioxidant, Anticancer and In Silico 5-LOX Inhibitory Evaluations S Mahgoub, N Hashad, S Ali, R Ibrahim, AM Said, FA Moharram, M Mady Molecules 26 (9), 2481, 2021 | 19 | 2021 |
| Novel pyrrolopyrimidine derivatives: design, synthesis, molecular docking, molecular simulations and biological evaluations as antioxidant and anti-inflammatory agents AI Sayed, YE Mansour, MA Ali, O Aly, ZM Khoder, AM Said, SS Fatahala, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1821-1837, 2022 | 14 | 2022 |
| Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance R Islam, J Mishra, NS Polavaram, S Bhattacharya, Z Hong, S Bodas, ... Cell reports 40 (3), 2022 | 12 | 2022 |
| Binding cooperativity between a ligand carbonyl group and a hydrophobic side chain can be enhanced by additional H-bonds in a distance dependent manner: A case study with … AM Said, DG Hangauer European Journal of Medicinal Chemistry 96, 405-424, 2015 | 12 | 2015 |
| Design, synthesis, and evaluation of a novel benzamidine-based inhibitor of VEGF-C binding to Neuropilin-2 AM Said, MW Parker, CW Vander Kooi Bioorganic chemistry 100, 103856, 2020 | 9 | 2020 |
| Modulating hydrogen-bond basicity within the context of protein-ligand binding: A case study with thrombin inhibitors that reveals a dominating role for desolvation NN Nasief, AM Said, D Hangauer European Journal of Medicinal Chemistry 125, 975-991, 2017 | 9 | 2017 |
| Design, synthesis, molecular modeling, in vitro and in vivo biological evaluation of potent anthranilamide derivatives as dual P-glycoprotein and CYP3A4 inhibitors AM Said, YE Mansour, RR Soliman, R Islam, SS Fatahala European Journal of Medicinal Chemistry 273, 116492, 2024 | 4 | 2024 |
| Ligand binding cooperativity: Bioisosteric replacement of CO with SO2 among thrombin inhibitors AM Said, DG Hangauer Bioorganic & Medicinal Chemistry Letters 26 (16), 3850-3854, 2016 | 4 | 2016 |
| Acetamido-phenyltetrazole derivatives and methods of using the same S Urgaonkar, AM Said, NNNA SAYED, LB Pitzonka, MJ Cutler, ... US Patent 11,739,089, 2023 | 2 | 2023 |
| Design, synthesis, molecular modelling and biological evaluation of novel 6-amino-5-cyano-2-thiopyrimidine derivatives as potent anticancer agents against leukemia and … NM Ahmed, MS Mohamed, SM Awad, NAA El-tawab, MS Gaballah, ... Journal of Enzyme Inhibition and Medicinal Chemistry 39 (1), 2304625, 2024 | 1 | 2024 |
| Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials FA Moharram, RR Ibrahim, S Mahgoub, MS Abdel-Aziz, AM Said, ... PloS one 20 (1), e0313616, 2025 | | 2025 |
| Acetamido-phenylbenzamide derivatives and methods of using the same S Urgaonkar, AM Said, NNNA SAYED, LB Pitzonka, MJ Cutler, ... US Patent App. 17/495,933, 2022 | | 2022 |
| Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations MPS Sameer Urgaonkar, Kamil Nosol, Ahmed M. Said, Nader N. Nasief, Yahao Bu ... ACS Journal of Medicinal Chemistry, 2021 | | 2021 |
| Towards more explicit understanding of the binding molecular aspects: hydrophobic-based cooperativity among series of thrombin inhibitors A Said, D Hangauer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
| Cooperativity and hydrophobic collapse can be potential factors for micro-molar to pico-molar change in binding affinity: A case study using thrombin inhibitors A Said, D Hangauer ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
Shahenda MahgoubAssociate professor of biochemistry and molecular biology faculty of pharmacy Helwan Universityยืนยันอีเมลแล้วที่ pharm.helwan.edu.eg
