Activation of GCN2 by the ribosomal P-stalk AJ Inglis, GR Masson, S Shao, O Perisic, SH McLaughlin, RS Hegde, ... Proceedings of the National Academy of Sciences 116 (11), 4946-4954, 2019 | 202 | 2019 |
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells HP Harding, A Ordonez, F Allen, L Parts, AJ Inglis, RL Williams, D Ron Elife 8, e50149, 2019 | 161 | 2019 |
Structural basis for membrane insertion by the human ER membrane protein complex T Pleiner, GP Tomaleri, K Januszyk, AJ Inglis, M Hazu, RM Voorhees Science 369 (6502), 433-436, 2020 | 152 | 2020 |
Structures of PI4KIIIβ complexes show simultaneous recruitment of Rab11 and its effectors JE Burke, AJ Inglis, O Perisic, GR Masson, SH McLaughlin, F Rutaganira, ... Science 344 (6187), 1035-1038, 2014 | 152 | 2014 |
Deconvolution of Buparlisib’s mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention T Bohnacker, AE Prota, F Beaufils, JE Burke, A Melone, AJ Inglis, ... Nature communications 8 (1), 14683, 2017 | 107 | 2017 |
MTCH2 is a mitochondrial outer membrane protein insertase A Guna, TA Stevens, AJ Inglis, JM Replogle, TK Esantsi, G Muthukumar, ... Science 378 (6617), 317-322, 2022 | 97 | 2022 |
Macromolecular condensation buffers intracellular water potential JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ... Nature 623 (7988), 842-852, 2023 | 66 | 2023 |
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology A Stangherlin, JL Watson, D Wong, S Barbiero, A Zeng, E Seinkmane, ... Nature communications 12 (1), 1-14, 2021 | 52 | 2021 |
Differential modes of orphan subunit recognition for the WRB/CAML complex AJ Inglis, KR Page, A Guna, RM Voorhees Cell reports 30 (11), 3691-3698. e5, 2020 | 28 | 2020 |
Coupled protein quality control during nonsense mediated mRNA decay AJ Inglis, A Guna, ÁG Merchán, A Pal, TK Esantsi, HR Keys, EM Frenkel, ... bioRxiv, 2021.12. 22.473893, 2021 | 21 | 2021 |
Disease variants of FGFR3 reveal molecular basis for the recognition and additional roles for Cdc37 in Hsp90 chaperone system TD Bunney, AJ Inglis, D Sanfelice, B Farrell, CJ Kerr, GS Thompson, ... Structure 26 (3), 446-458. e8, 2018 | 18 | 2018 |
The centriolar protein CPAP G-box: an amyloid fibril in a single domain EE Cutts, A Inglis, PJ Stansfeld, I Vakonakis, GN Hatzopoulos Biochemical Society Transactions 43 (5), 838-843, 2015 | 8 | 2015 |
Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology G Muthukumar, TA Stevens, AJ Inglis, TK Esantsi, RA Saunders, F Schulte, ... Molecular Cell, 2024 | 5 | 2024 |
Structural and functional characterisation of the nutrient sensing kinase GCN2 A Inglis University of Cambridge, 2018 | 3 | 2018 |
BKM120-mediated G2 arrest: Structural and functional segregation of off-target action and PI3K inhibition T Bohnacker, F Beaufils, AE Prota, JE Burke, A Melone, AJ Inglis, L Fusco, ... Cancer Research 75 (15_Supplement), 671-671, 2015 | 3 | 2015 |
Publisher Correction: Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology A Stangherlin, JL Watson, D Wong, S Barbiero, A Zeng, E Seinkmane, ... Nature Publishing Group UK, 2021 | 1 | 2021 |
Abstract IA02: G-proteins regulating PI3Ks and PI4KIIIβ regulating a G-protein JE Burke, AJ Inglis, O Vadas, O Perisic, GR Masson, SH McLaughlin, ... Molecular Cancer Therapeutics 14 (7_Supplement), IA02-IA02, 2015 | 1 | 2015 |
Triaging of⍺-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology G Muthukumar, TA Stevens, AJ Inglis, TK Esantsi, RA Saunders, F Schulte, ... bioRxiv, 2023.08. 16.553624, 2023 | | 2023 |
Abstract A32: The role of the ribosome in GCN2's ability to sense amino acid deprivation and initiate the integrated stress response AJ Inglis, S Shao, GR Masson, O Perisic, RS Hegde, RL Williams Cancer Research 77 (6_Supplement), A32-A32, 2017 | | 2017 |