ติดตาม
Jochen Weile
Jochen Weile
University of Toronto
ยืนยันอีเมลแล้วที่ mail.utoronto.ca
ชื่อ
อ้างโดย
อ้างโดย
ปี
A reference map of the human binary protein interactome
K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ...
Nature 580 (7803), 402-408, 2020
10852020
Widespread macromolecular interaction perturbations in human genetic disorders
N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ...
Cell 161 (3), 647-660, 2015
6062015
MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect
D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ...
Genome biology 20, 1-11, 2019
2302019
A framework for exhaustively mapping functional missense variants
J Weile, S Sun, AG Cote, J Knapp, M Verby, JC Mellor, Y Wu, C Pons, ...
Molecular systems biology 13 (12), 957, 2017
2022017
Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas
J Weile, FP Roth
Human genetics 137 (9), 665-678, 2018
1502018
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
N Yachie, E Petsalaki, JC Mellor, J Weile, Y Jacob, M Verby, SB Ozturk, ...
Molecular systems biology 12 (4), 863, 2016
1372016
Improved pathogenicity prediction for rare human missense variants
Y Wu, H Liu, R Li, S Sun, J Weile, FP Roth
The American Journal of Human Genetics 108 (10), 1891-1906, 2021
1222021
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation
GS Karagiannis, J Weile, GD Bader, J Minta
BMC cardiovascular disorders 13, 1-19, 2013
792013
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase
S Sun, J Weile, M Verby, Y Wu, Y Wang, AG Cote, I Fotiadou, ...
Genome medicine 12, 1-18, 2020
622020
KeyPathwayMiner: detecting case-specific biological pathways using expression data
N Alcaraz, H Kücük, J Weile, A Wipat, J Baumbach
Internet Mathematics 7 (4), 299-313, 2011
622011
Systematic analysis of bypass suppression of essential genes
J Van Leeuwen, C Pons, G Tan, ZY Wang, J Hou, J Weile, M Gebbia, ...
Molecular systems biology 16 (9), 1-24, 2020
542020
Shifting landscapes of human MTHFR missense-variant effects
J Weile, N Kishore, S Sun, R Maaieh, M Verby, R Li, I Fotiadou, ...
The American Journal of Human Genetics 108 (7), 1283-1300, 2021
532021
An integrated dataset for in silico drug discovery
SJ Cockell, J Weile, P Lord, C Wipat, D Andriychenko, M Pocock, ...
Journal of integrative bioinformatics 7 (3), 15-27, 2010
492010
A comprehensive map of human glucokinase variant activity
S Gersing, M Cagiada, M Gebbia, AP Gjesing, AG Coté, G Seesankar, ...
Genome Biology 24 (1), 97, 2023
422023
A reference map of the human protein interactome
K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ...
BioRxiv, 605451, 2019
352019
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
Genome biology 25 (1), 53, 2024
322024
Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics
JJ Díaz‐Mejía, A Celaj, JC Mellor, A Coté, A Balint, B Ho, P Bansal, ...
Molecular Systems Biology 14 (5), e7985, 2018
312018
MaveRegistry: a collaboration platform for multiplexed assays of variant effect
D Kuang, J Weile, N Kishore, M Nguyen, AF Rubin, S Fields, DM Fowler, ...
Bioinformatics 37 (19), 3382-3383, 2021
242021
A web application and service for imputing and visualizing missense variant effect maps
Y Wu, J Weile, AG Cote, S Sun, J Knapp, M Verby, FP Roth
Bioinformatics 35 (17), 3191-3193, 2019
202019
Assessing predictions of fitness effects of missense mutations in SUMO‐conjugating enzyme UBE2I
J Zhang, LN Kinch, Q Cong, J Weile, S Sun, AG Cote, FP Roth, NV Grishin
Human Mutation 38 (9), 1051-1063, 2017
182017
ระบบไม่สามารถดำเนินการได้ในขณะนี้ โปรดลองใหม่อีกครั้งในภายหลัง
บทความ 1–20