Evidence for a stromal-epithelial “lactate shuttle” in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts D Whitaker-Menezes, UE Martinez-Outschoorn, Z Lin, A Ertel, ... Cell cycle 10 (11), 1772-1783, 2011 | 464 | 2011 |
Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo … UE Martinez-Outschoorn, M Prisco, A Ertel, A Tsirigos, Z Lin, S Pavlides, ... Cell cycle 10 (8), 1271-1286, 2011 | 434 | 2011 |
The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression A Sharma, WS Yeow, A Ertel, I Coleman, N Clegg, C Thangavel, ... The Journal of clinical investigation 120 (12), 4478-4492, 2010 | 369 | 2010 |
Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue D Whitaker-Menezes, UE Martinez-Outschoorn, N Flomenberg, R Birbe, ... Cell cycle 10 (23), 4047-4064, 2011 | 364 | 2011 |
Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer C Thangavel, JL Dean, A Ertel, KE Knudsen, CM Aldaz, AK Witkiewicz, ... Endocrine-related cancer 18 (3), 333, 2011 | 352 | 2011 |
CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer CellsAntimetastatic Effect of CCR5 Antagonist M Velasco-Velázquez, X Jiao, M De La Fuente, TG Pestell, A Ertel, ... Cancer research 72 (15), 3839-3850, 2012 | 341 | 2012 |
Functional significance of macrophage-derived exosomes in inflammation and pain MK McDonald, Y Tian, RA Qureshi, M Gormley, A Ertel, R Gao, EA Lopez, ... PAIN® 155 (8), 1527-1539, 2014 | 339 | 2014 |
Pathway-specific differences between tumor cell lines and normal and tumor tissue cells A Ertel, A Verghese, SW Byers, M Ochs, A Tozeren Molecular cancer 5 (1), 1-13, 2006 | 284 | 2006 |
Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3 EV Abel, KJ Basile, CH Kugel, AK Witkiewicz, K Le, RK Amaravadi, ... The Journal of clinical investigation 123 (5), 2155-2168, 2013 | 269 | 2013 |
RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response A Ertel, JL Dean, H Rui, C Liu, A Witkiewicz, KE Knudsen, ES Knudsen Cell cycle 9 (20), 4153-4163, 2010 | 205 | 2010 |
The complex transcriptional landscape of the anucleate human platelet PF Bray, SE McKenzie, LC Edelstein, S Nagalla, K Delgrosso, A Ertel, ... BMC genomics 14 (1), 1-15, 2013 | 189 | 2013 |
Blockade of tumor-expressed PD-1 promotes lung cancer growth S Du, N McCall, K Park, Q Guan, P Fontina, A Ertel, T Zhan, AP Dicker, ... Oncoimmunology 7 (4), e1408747, 2018 | 142 | 2018 |
ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in mice MC Casimiro, M Crosariol, E Loro, A Ertel, Z Yu, W Dampier, EA Saria, ... The Journal of clinical investigation 122 (3), 833-843, 2012 | 140 | 2012 |
Nuclear pores promote lethal prostate cancer by increasing POM121-driven E2F1, MYC, and AR nuclear import V Rodriguez-Bravo, R Pippa, WM Song, M Carceles-Cordon, ... Cell 174 (5), 1200-1215. e20, 2018 | 126 | 2018 |
Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia ES Knudsen, A Ertel, E Davicioni, J Kline, GF Schwartz, AK Witkiewicz Breast cancer research and treatment 133 (3), 1009-1024, 2012 | 108 | 2012 |
EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1Phosphatase Function of the EYA1 in Breast Cancer K Wu, Z Li, S Cai, L Tian, K Chen, J Wang, J Hu, Y Sun, X Li, A Ertel, ... Cancer research 73 (14), 4488-4499, 2013 | 107 | 2013 |
RB Loss Promotes Prostate Cancer MetastasisRB Inhibits Tumor Metastasis C Thangavel, E Boopathi, Y Liu, A Haber, A Ertel, A Bhardwaj, S Addya, ... Cancer research 77 (4), 982-995, 2017 | 99 | 2017 |
Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers AK Witkiewicz, J Kline, M Queenan, JR Brody, A Tsirigos, E Bilal, ... Cell cycle 10 (11), 1794-1809, 2011 | 99 | 2011 |
Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes AR Peck, AK Witkiewicz, C Liu, AC Klimowicz, GA Stringer, E Pequignot, ... Breast Cancer Research 14 (5), 1-16, 2012 | 96 | 2012 |
High-resolution SNP arrays in mental retardation diagnostics: how much do we gain? L Bernardini, V Alesi, S Loddo, A Novelli, I Bottillo, A Battaglia, MC Digilio, ... European Journal of Human Genetics 18 (2), 178-185, 2010 | 93 | 2010 |