Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 JG Doench, N Fusi, M Sullender, M Hegde, EW Vaimberg, KF Donovan, ... Nature biotechnology 34 (2), 184-191, 2016 | 4391 | 2016 |
Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation JG Doench, E Hartenian, DB Graham, Z Tothova, M Hegde, I Smith, ... Nature biotechnology 32 (12), 1262-1267, 2014 | 1870 | 2014 |
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities KR Sanson, RE Hanna, M Hegde, KF Donovan, C Strand, ME Sullender, ... Nature communications 9 (1), 5416, 2018 | 836 | 2018 |
Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens FJ Najm, C Strand, KF Donovan, M Hegde, KR Sanson, EW Vaimberg, ... Nature biotechnology 36 (2), 179-189, 2018 | 308 | 2018 |
Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ H Ingle, S Lee, T Ai, A Orvedahl, R Rodgers, G Zhao, M Sullender, ... Nature microbiology 4 (7), 1120-1128, 2019 | 105 | 2019 |
A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair JR Brickner, JM Soll, PM Lombardi, CB Vågbø, MC Mudge, C Oyeniran, ... Nature 551 (7680), 389-393, 2017 | 101 | 2017 |
Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities. Nat. Commun. 9, 5416 KR Sanson, RE Hanna, M Hegde, KF Donovan, C Strand, ME Sullender, ... First published on Dec 21, 2018, 2018 | 74 | 2018 |
Creation of novel protein variants with CRISPR/Cas9-mediated mutagenesis: turning a screening by-product into a discovery tool KF Donovan, M Hegde, M Sullender, EW Vaimberg, CM Johannessen, ... PloS one 12 (1), e0170445, 2017 | 61 | 2017 |
Identification of antinorovirus genes in human cells using genome-wide CRISPR activation screening RC Orchard, ME Sullender, BF Dunlap, DR Balce, JG Doench, HW Virgin Journal of virology 93 (1), 10.1128/jvi. 01324-18, 2019 | 56 | 2019 |
Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans MA McShea, KL Schmidt, ML Dubuke, CE Baldiga, ME Sullender, AL Reis, ... Developmental biology 373 (1), 1-13, 2013 | 35 | 2013 |
Norovirus interactions with the commensal microbiota ME Sullender, MT Baldridge PLoS pathogens 14 (9), e1007183, 2018 | 29 | 2018 |
Rotavirus susceptibility of antibiotic-treated mice ascribed to diminished expression of interleukin-22 D Schnepf, P Hernandez, T Mahlakõiv, S Crotta, ME Sullender, ... PloS One 16 (8), e0247738, 2021 | 16 | 2021 |
Up, down, and out: next generation libraries for genome-wide CRISPRa, CRISPRi, and CRISPR-Cas9 knockout genetic screens KR Sanson, RE Hanna, M Hegde, KF Donovan, C Strand, ME Sullender, ... bioRxiv, 356626, 2018 | 10 | 2018 |
Selective polyprotein processing determines norovirus sensitivity to Trim7 ME Sullender, LR Pierce, M Annaswamy Srinivas, SL Crockett, BF Dunlap, ... Journal of virology 96 (17), e00707-22, 2022 | 8 | 2022 |
Autophagy gene-dependent intracellular immunity triggered by interferon-γ MR McAllaster, J Bhushan, DR Balce, A Orvedahl, A Park, S Hwang, ... MBio 14 (6), e02332-23, 2023 | 5 | 2023 |
The neonatal Fc receptor (FcRn) is a pan-arterivirus receptor TM Shaw, D Huey, M Mousa-Makky, J Compaleo, K Nennig, AP Shah, ... Nature communications 15 (1), 6726, 2024 | 2 | 2024 |
CRISPR/Cas9 screens identify key host factors that enhance rotavirus reverse genetics efficacy and vaccine production Y Zhu, ME Sullender, DE Campbell, L Wang, S Lee, T Kawagishi, G Hou, ... npj Vaccines 9 (1), 211, 2024 | 1 | 2024 |
Viral complementation of immunodeficiency confers protection against enteric pathogens via interferon-λ I Harshad, S Lee, T Ai, O Anthony, R Rodgers, Z Guoyan, S Meagan, ... Nature Microbiology 4 (7), 1120-1128, 2019 | 1 | 2019 |
Do ARX-3 and CSN-5 Protein Subunits Interact with MIG-10 to Promote Axon Outgrowth and Neuronal Migration in C. elegans? ME Sullender Worcester Polytechnic Institute, 2012 | 1 | 2012 |
Dynamics of Bacterial and Viral Transmission in Experimental Microbiota Transplantation J Weagley, H Makimaa, LAC Cardenas, A Romani, M Sullender, ... bioRxiv, 2025.01. 15.633206, 2025 | | 2025 |