| Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative A Biddle, X Liang, L Gammon, B Fazil, LJ Harper, H Emich, DE Costea, ... Cancer research 71 (15), 5317-5326, 2011 | 415 | 2011 |
| Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma DE Costea, A Hills, AH Osman, J Thurlow, G Kalna, X Huang, ... Cancer research 73 (13), 3888-3901, 2013 | 201 | 2013 |
| MicroRNA alterations and associated aberrant DNA methylation patterns across multiple sample types in oral squamous cell carcinoma ED Wiklund, S Gao, T Hulf, T Sibbritt, S Nair, DE Costea, SB Villadsen, ... PLoS one 6 (11), e27840, 2011 | 199 | 2011 |
| Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography EM Guerreiro, B Vestad, LA Steffensen, HCD Aass, M Saeed, R Øvstebø, ... PloS one 13 (9), e0204276, 2018 | 170 | 2018 |
| Cancer stem cells–new and potentially important targets for the therapy of oral squamous cell carcinoma DE Costea, O Tsinkalovsky, OK Vintermyr, AC Johannessen, ... Oral diseases 12 (5), 443-454, 2006 | 161 | 2006 |
| Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance LJ Harper, DE Costea, L Gammon, B Fazil, A Biddle, IC Mackenzie BMC cancer 10, 1-16, 2010 | 141 | 2010 |
| Phenotypic plasticity determines cancer stem cell therapeutic resistance in oral squamous cell carcinoma A Biddle, L Gammon, X Liang, DE Costea, IC Mackenzie EBioMedicine 4, 138-145, 2016 | 139 | 2016 |
| Cancer, pre-cancer and normal oral cells distinguished by dielectrophoresis HJ Mulhall, FH Labeed, B Kazmi, DE Costea, MP Hughes, MP Lewis Analytical and bioanalytical chemistry 401, 2455-2463, 2011 | 126 | 2011 |
| Crucial effects of fibroblasts and keratinocyte growth factor on morphogenesis of reconstituted human oral epithelium OK Vintermyr, DE Costea, LL Loro, EAO Dimba, AC Johannessen Journal of investigative dermatology 121 (6), 1479-1486, 2003 | 125 | 2003 |
| MicroRNAs as important players and biomarkers in oral carcinogenesis A Min, C Zhu, S Peng, S Rajthala, DE Costea, D Sapkota BioMed research international 2015 (1), 186904, 2015 | 121 | 2015 |
| Molecular crosstalk between cancer cells and tumor microenvironment components suggests potential targets for new therapeutic approaches in mobile tongue cancer D Dayan, T Salo, S Salo, P Nyberg, S Nurmenniemi, DE Costea, M Vered Cancer medicine 1 (2), 128-140, 2012 | 90 | 2012 |
| Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and-8 in human leukaemia cells EAO Dimba, BT Gjertsen, T Bredholt, KO Fossan, DE Costea, GW Francis, ... British Journal of Cancer 91 (9), 1726-1734, 2004 | 90 | 2004 |
| α11β1 integrin is induced in a subset of cancer-associated fibroblasts in desmoplastic tumor stroma and mediates in vitro cell migration C Zeltz, J Alam, H Liu, PM Erusappan, H Hoschuetzky, A Molven, ... Cancers 11 (6), 765, 2019 | 79 | 2019 |
| Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression H Parajuli, MT Teh, S Abrahamsen, I Christoffersen, E Neppelberg, ... Journal of Oral Pathology & Medicine 46 (4), 267-275, 2017 | 74 | 2017 |
| S100A14 regulates the invasive potential of oral squamous cell carcinoma derived cell-lines in vitro by modulating expression of matrix metalloproteinases, MMP1 and MMP9 D Sapkota, O Bruland, DE Costea, H Haugen, EN Vasstrand, SO Ibrahim European Journal of Cancer 47 (4), 600-610, 2011 | 68 | 2011 |
| Dual effects of sodium lauryl sulphate on human oral epithelial structure E Neppelberg, DE Costea, OK Vintermyr, AC Johannessen Experimental dermatology 16 (7), 574-579, 2007 | 67 | 2007 |
| Metabolic reprogramming of normal oral fibroblasts correlated with increased glycolytic metabolism of oral squamous cell carcinoma and precedes their activation into carcinoma … Z Zhang, Z Gao, S Rajthala, D Sapkota, H Dongre, H Parajuli, S Suliman, ... Cellular and Molecular Life Sciences 77, 1115-1133, 2020 | 66 | 2020 |
| The changing face of p53 in head and neck cancer M Partridge, DE Costea, X Huang International journal of oral and maxillofacial surgery 36 (12), 1123-1138, 2007 | 66 | 2007 |
| A co-culture model with brain tumor-specific bioluminescence demonstrates astrocyte-induced drug resistance in glioblastoma N Yang, T Yan, H Zhu, X Liang, L Leiss, PØ Sakariassen, KO Skaftnesmo, ... Journal of translational medicine 12, 1-9, 2014 | 62 | 2014 |
| In vitro reconstruction of human junctional and sulcular epithelium G Dabija‐Wolter, V Bakken, MR Cimpan, AC Johannessen, DE Costea Journal of oral pathology & medicine 42 (5), 396-404, 2013 | 52 | 2013 |
