Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity E Volz, V Hill, JT McCrone, A Price, D Jorgensen, Á O’Toole, J Southgate, ... Cell 184 (1), 64-75. e11, 2021 | 1175 | 2021 |
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ... The Lancet Infectious Diseases 22 (1), 35-42, 2022 | 937 | 2022 |
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection T Charalampous, GL Kay, H Richardson, A Aydin, R Baldan, C Jeanes, ... Nature biotechnology 37 (7), 783-792, 2019 | 539 | 2019 |
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B. 1.1. 7 B Meng, SA Kemp, G Papa, R Datir, IATM Ferreira, S Marelli, WT Harvey, ... Cell reports 35 (13), 2021 | 479 | 2021 |
Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B. 1.1. 7: an ecological study MS Graham, CH Sudre, A May, M Antonelli, B Murray, T Varsavsky, ... The Lancet Public Health 6 (5), e335-e345, 2021 | 366 | 2021 |
Comparative performance of SARS-CoV-2 lateral flow antigen tests and association with detection of infectious virus in clinical specimens: a single-centre laboratory evaluation … S Pickering, R Batra, B Merrick, LB Snell, G Nebbia, S Douthwaite, F Reid, ... The Lancet Microbe 2 (9), e461-e471, 2021 | 136 | 2021 |
Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern L Dupont, LB Snell, C Graham, J Seow, B Merrick, T Lechmere, ... Nature microbiology 6 (11), 1433-1442, 2021 | 105 | 2021 |
Genomic reconstruction of the SARS-CoV-2 epidemic in England HS Vöhringer, T Sanderson, M Sinnott, N De Maio, T Nguyen, R Goater, ... Nature 600 (7889), 506-511, 2021 | 103 | 2021 |
Rapid inference of antibiotic resistance and susceptibility by genomic neighbour typing K Břinda, A Callendrello, KC Ma, DR MacFadden, T Charalampous, ... Nature microbiology 5 (3), 455-464, 2020 | 103 | 2020 |
Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study L Yang, G Haidar, H Zia, R Nettles, S Qin, X Wang, F Shah, SF Rapport, ... Respiratory research 20, 1-12, 2019 | 87 | 2019 |
The impact of viral mutations on recognition by SARS-CoV-2 specific T cells TI de Silva, G Liu, BB Lindsey, D Dong, SC Moore, NS Hsu, D Shah, ... IScience 24 (11), 2021 | 76 | 2021 |
Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units T Charalampous, A Alcolea-Medina, LB Snell, TGS Williams, R Batra, ... Genome medicine 13, 1-16, 2021 | 50 | 2021 |
The ongoing Streptococcus pyogenes (Group A Streptococcus) outbreak in London, United Kingdom, in December 2022: a molecular epidemiology study A Alcolea-Medina, LB Snell, C Alder, T Charalampous, TGS Williams, ... Clinical Microbiology and Infection 29 (7), 887-890, 2023 | 38 | 2023 |
SARS-CoV-2 lineage B. 1.1. 7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study O Stirrup, F Boshier, C Venturini, JA Guerra-Assunção, A Alcolea-Medina, ... BMJ open respiratory research 8 (1), e001029, 2021 | 38 | 2021 |
Broad neutralization of SARS-CoV-2 variants, including omicron, following breakthrough infection with Delta in COVID-19-vaccinated individuals T Lechmere, LB Snell, C Graham, J Seow, ZA Shalim, T Charalampous, ... Mbio 13 (2), e03798-21, 2022 | 37 | 2022 |
Rapid diagnosis of lower respiratory infection using nanopore-based clinical metagenomics T Charalampous, H Richardson, GL Kay, R Baldan, C Jeanes, D Rae, ... BioRxiv, 387548, 2018 | 31 | 2018 |
Lineage calling can identify antibiotic resistant clones within minutes K Břinda, A Callendrello, L Cowley, T Charalampous, RS Lee, ... bioRxiv 403204, 455-464, 2018 | 30 | 2018 |
Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission LB Snell, CL Fisher, U Taj, O Stirrup, B Merrick, A Alcolea-Medina, ... Clinical Microbiology and Infection 28 (1), 93-100, 2022 | 28 | 2022 |
Routine metagenomics service for ICU patients with respiratory infection T Charalampous, A Alcolea-Medina, LB Snell, C Alder, M Tan, ... American Journal of Respiratory and Critical Care Medicine 209 (2), 164-174, 2024 | 22 | 2024 |
Rapid genome sequencing in hospitals to identify potential vaccine-escape SARS-CoV-2 variants LB Snell, PR Cliff, T Charalampous, A Alcolea-Medina, SART Ebie, ... The Lancet Infectious Diseases 21 (10), 1351-1352, 2021 | 22 | 2021 |