| G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 227 | 2018 |
| Pharmacological inhibition of the transcription factor PU. 1 in leukemia I Antony-Debré, A Paul, J Leite, K Mitchell, HM Kim, LA Carvajal, ... The Journal of clinical investigation 127 (12), 4297-4313, 2017 | 124 | 2017 |
| Synthesis, molecular modeling and anticancer activity of new coumarin containing compounds SA Morsy, AA Farahat, MNA Nasr, AS Tantawy Saudi Pharmaceutical Journal 25 (6), 873-883, 2017 | 84 | 2017 |
| Structure-dependent inhibition of the ETS-family transcription factor PU. 1 by novel heterocyclic diamidines M Munde, S Wang, A Kumar, CE Stephens, AA Farahat, DW Boykin, ... Nucleic acids research 42 (2), 1379-1390, 2014 | 84 | 2014 |
| Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines R Nhili, P Peixoto, S Depauw, S Flajollet, X Dezitter, MM Munde, ... Nucleic acids research 41 (1), 125-138, 2013 | 77 | 2013 |
| Water-mediated binding of agents that target the DNA minor groove Y Liu, A Kumar, S Depauw, R Nhili, MH David-Cordonnier, MP Lee, ... Journal of the American Chemical Society 133 (26), 10171-10183, 2011 | 73 | 2011 |
| Indole and benzimidazole bichalcophenes: Synthesis, DNA binding and antiparasitic activity AA Farahat, MA Ismail, A Kumar, T Wenzler, R Brun, A Paul, WD Wilson, ... European journal of medicinal chemistry 143, 1590-1596, 2018 | 70 | 2018 |
| 2-Chloroquinoline-3-carbaldehydes: synthesis, reactions and applications BF Abdel-Wahab, RE Khidre, AA Farahat, AAS El-Ahl Arkivoc 2012, 211-276, 2012 | 66 | 2012 |
| Pyrazole-3 (4)-carbaldehyde: synthesis, reactions and biological activity. BF Abdel-Wahab, RE Khidre, AA Farahat ARKIVOC: Online Journal of Organic Chemistry, 2011 | 66 | 2011 |
| In Vitro and In Vivo Investigation of the Efficacy of Arylimidamide DB1831 and Its Mesylated Salt Form - DB1965 - against Trypanosoma cruzi Infection CF da Silva, DGJ Batista, GM Oliveira, EM de Souza, ER Hammer, ... PLoS One 7 (1), e30356, 2012 | 52 | 2012 |
| Synthesis and antiprotozoal activity of 2, 5-bis [amidinoaryl] thiazoles D Branowska, AA Farahat, A Kumar, T Wenzler, R Brun, Y Liu, WD Wilson, ... Bioorganic & Medicinal Chemistry 18 (10), 3551-3558, 2010 | 51 | 2010 |
| DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site M Munde, A Kumar, R Nhili, S Depauw, MH David-Cordonnier, MA Ismail, ... Journal of molecular biology 402 (5), 847-864, 2010 | 50 | 2010 |
| 2-Amino-4-thiazolidinones: synthesis and reactions MA Metwally, AA Farahat, BF Abdel-Wahab Journal of Sulfur Chemistry 31 (4), 315-349, 2010 | 47 | 2010 |
| Ethyl coumarin-3-carboxylate: synthesis and chemical properties BF Abdel-Wahab, HA Mohamed, AA Farahat. Organic. Communications. 2014, 7, 1-27. 7, 1-27, 2014 | 46 | 2014 |
| Exploration of larger central ring linkers in furamidine analogues: synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties AA Farahat, E Paliakov, A Kumar, AEM Barghash, FE Goda, HM Eisa, ... Bioorganic & medicinal chemistry 19 (7), 2156-2167, 2011 | 46 | 2011 |
| Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines AA Farahat, A Kumar, M Say, AEDM Barghash, FE Goda, HM Eisa, ... Bioorganic & medicinal chemistry 18 (2), 557-566, 2010 | 44 | 2010 |
| 1H‐Benzimidazole‐2‐acetonitriles as synthon in fused benzimidazole synthesis KM Dawood, NM Elwan, AA Farahat, BF Abdel‐Wahab Journal of Heterocyclic Chemistry 47 (2), 243-267, 2010 | 41 | 2010 |
| Heterocyclic diamidine DNA ligands as HOXA9 transcription factor inhibitors: Design, molecular evaluation, and cellular consequences in a HOXA9-dependant leukemia cell model S Depauw, M Lambert, S Jambon, A Paul, P Peixoto, R Nhili, L Marongiu, ... Journal of medicinal chemistry 62 (3), 1306-1329, 2019 | 40 | 2019 |
| Pharmacologic efficacy of PU. 1 inhibition by heterocyclic dications: a mechanistic analysis DC Stephens, HM Kim, A Kumar, AA Farahat, DW Boykin, GM Poon Nucleic acids research 44 (9), 4005-4013, 2016 | 40 | 2016 |
| The Thiophene “Sigma‐Hole” as a Concept for Preorganized, Specific Recognition of G⋅ C Base Pairs in the DNA Minor Groove P Guo, A Paul, A Kumar, AA Farahat, D Kumar, S Wang, DW Boykin, ... Chemistry–A European Journal 22 (43), 15404-15412, 2016 | 39 | 2016 |
Ananya PaulResearch Scientist I, Georgia State Universityยืนยันอีเมลแล้วที่ gsu.edu
