| Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a … MJ O'Dwyer, F Dempsey, V Crowley, DP Kelleher, R McManus, T Ryan Critical Care 10 (5), R139, 2006 | 136 | 2006 |
| Features of postoperative immune suppression are reversible with interferon gamma and independent of interleukin-6 Pathways ER Longbottom, HDT Torrance, HC Owen, PC Fragkou, CJ Hinds, ... Annals of surgery 264 (2), 370-377, 2016 | 107 | 2016 |
| The perioperative immune response MJ O’Dwyer, HC Owen, HDT Torrance Current opinion in critical care 21 (4), 336-342, 2015 | 96 | 2015 |
| Systemic inflammatory response syndrome after major abdominal surgery predicted by early upregulation of TLR4 and TLR5 R Lahiri, Y Derwa, Z Bashir, E Giles, HDT Torrance, HC Owen, ... Annals of surgery 263 (5), 1028-1037, 2016 | 67 | 2016 |
| The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression MJ O'Dwyer, AK Mankan, P Stordeur, B O'Connell, E Duggan, M White, ... Shock 26 (4), 5-6, 2006 | 66 | 2006 |
| Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients HDT Torrance, K Brohi, RM Pearse, CA Mein, E Wozniak, JR Prowle, ... Annals of surgery 261 (4), 751-759, 2015 | 64 | 2015 |
| Does major surgery induce immune suppression and increase the risk of postoperative infection? HDT Torrance, RM Pearse, MJ O’Dwyer Current Opinion in Anesthesiology 29 (3), 376-383, 2016 | 63 | 2016 |
| Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses MW Lawless, AK Mankan, M White, MJ O'Dwyer, S Norris BMC cell biology 8 (1), 30, 2007 | 54 | 2007 |
| Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study PC Fragkou, HD Torrance, RM Pearse, GL Ackland, JR Prowle, HC Owen, ... Critical care 18 (5), 541, 2014 | 45 | 2014 |
| The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression MJ O’Dwyer, AK Mankan, M White, MW Lawless, P Stordeur, B O’Connell, ... Intensive care medicine 34 (4), 683-691, 2008 | 40 | 2008 |
| Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression M White, I Martin-Loeches, MW Lawless, MJ O’Dwyer, DG Doherty, ... CHEST Journal 139 (3), 626-632, 2011 | 34 | 2011 |
| Gene polymorphism and requirement for vasopressor infusion after cardiac surgery R Ryan, J Thornton, E Duggan, E McGovern, MJ O’Dwyer, AW Ryan, ... The Annals of thoracic surgery 82 (3), 895-901, 2006 | 34 | 2006 |
| The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis—a prospective multi-centre European … MJ O’Dwyer, MH Starczewska, J Schrenzel, K Zacharowski, DJ Ecker, ... Clinical Microbiology and Infection, 2016 | 32 | 2016 |
| Tumor necrosis factor-α and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery E Duggan, E Caraher, K Gately, M O'Dwyer, E McGovern, D Kelleher, ... Critical care medicine 34 (8), 2134-2139, 2006 | 32 | 2006 |
| Transforming growth factor β-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection M White, MW Lawless, MJ O’Dwyer, R Grealy, BO Connell, P Stordeur, ... Cytokine 50 (3), 322-327, 2010 | 26 | 2010 |
| Elevated MCP‐1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis MW Lawless, M White, AK Mankan, MJ O’Dwyer, S Norris Tissue antigens 70 (4), 294-300, 2007 | 26 | 2007 |
| Coagulopathy after cardiac surgery may be influenced by a functional plasminogen activator inhibitor polymorphism E Duggan, MJ O’dwyer, E Caraher, D Diviney, E McGovern, D Kelleher, ... Anesthesia & Analgesia 104 (6), 1343-1347, 2007 | 26 | 2007 |
| Changes in gene expression following trauma are related to the age of transfused packed red blood cells HDT Torrance, ME Vivian, K Brohi, JR Prowle, RM Pearse, HC Owen, ... Journal of Trauma and Acute Care Surgery 78 (3), 535-542, 2015 | 24 | 2015 |
| Epigenetic regulatory pathways involving microRNAs may modulate the host immune response following major trauma HC Owen, HDT Torrance, TF Jones, RM Pearse, CJ Hinds, K Brohi, ... Journal of Trauma and Acute Care Surgery 79 (5), 766-772, 2015 | 18 | 2015 |
| Characterization of tumour necrosis factor‐alpha genetic variants and mRNA expression in patients with severe sepsis MJ O'Dwyer, AK Mankan, AW Ryan, MW Lawless, P Stordeur, D Kelleher, ... International journal of immunogenetics 35 (4‐5), 279-285, 2008 | 15 | 2008 |
