| Neurofilaments consist of distinct populations that can be distinguished by C-terminal phosphorylation, bundling, and axonal transport rate in growing axonal neurites JT Yabe, T Chylinski, FS Wang, A Pimenta, SD Kattar, MD Linsley, ... Journal of Neuroscience 21 (7), 2195-2205, 2001 | 132 | 2001 |
| Therapeutic compounds J Katz, J Jewell, J Jung, S Kattar, Y Hou, R MacCoss, S Ito US Patent 8,455,477, 2013 | 55 | 2013 |
| Spirocyclic compounds SC Berk, J Close, C Hamblett, RW Heidebrecht, SD Kattar, LT Kliman, ... US Patent 7,544,695, 2009 | 49 | 2009 |
| Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1: 2) optimization SD Kattar, LM Surdi, A Zabierek, JL Methot, RE Middleton, B Hughes, ... Bioorganic & Medicinal Chemistry Letters 19 (4), 1168-1172, 2009 | 41 | 2009 |
| Discovery of a chemical probe for PRDM9 A Allali-Hassani, MM Szewczyk, D Ivanochko, SL Organ, J Bok, JSY Ho, ... Nature Communications 10 (1), 5759, 2019 | 39 | 2019 |
| Aminopyrimidines as Syk inhibitors MD Altman, KL Arrington, J Burch, B Cote, JF Fournier, JY Gauthier, ... US Patent 8,735,417, 2014 | 37 | 2014 |
| Structure-guided discovery of aminoquinazolines as brain-penetrant and selective LRRK2 inhibitors MH Keylor, A Gulati, SD Kattar, RE Johnson, RW Chau, KA Margrey, ... Journal of medicinal chemistry 65 (1), 838-856, 2021 | 32 | 2021 |
| Inhibitors of IRAK4 activity MD Altman, JD Brubaker, ML Childers, A Donofrio, T Fischmann, ... US Patent 9,926,330, 2018 | 31 | 2018 |
| Aminopyrimidines as SYK inhibitors MD Altman, BM Andresen, KL Arrington, J Burch, KK Childers, B Cote, ... US Patent 8,551,984, 2013 | 26 | 2013 |
| Phosphorus derivatives as histone deacetylase inhibitors J Close, J Grimm, RW Heidebrecht, S Kattar, TA Miller, KM Otte, ... US Patent 7,981,874, 2011 | 22 | 2011 |
| Triazolyl derivatives as Syk inhibitors MR Machacek, ET Romeo, SD Kattar, M Christopher, MD Altman, ... US Patent 9,586,931, 2017 | 20 | 2017 |
| 4-carboxybenzylamino derivatives as histone deacetylase inhibitors P Harrington, S Kattar, TA Miller, MG Stanton, P Tempest, DJ Witter US Patent 8,389,553, 2013 | 18 | 2013 |
| Spirocyclic compounds SC Berk, J Close, C Hamblett, RW Heidebrecht, SD Kattar, LT Kliman, ... US Patent 7,834,026, 2010 | 18 | 2010 |
| Bipyridylaminopyridines as Syk inhibitors D Deschenes, MD Altman, JM Ellis, C Fischer, AM Haidle, SD Kattar, ... US Patent 9,145,391, 2015 | 16 | 2015 |
| Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease DA Candito, V Simov, A Gulati, S Kattar, RW Chau, BT Lapointe, ... Journal of Medicinal Chemistry 65 (24), 16801-16817, 2022 | 15 | 2022 |
| Substituted pyridine spleen tyrosine kinase (SYK) inhibitors AM Haidle, SL Knowles, SD Kattar, D Deschenes, J Burch, J Robichaud, ... US Patent 9,376,418, 2016 | 15 | 2016 |
| Aminopyrimidines as Syk inhibitors MD Altman, KK Childers, ME Di Francesco, JM Ellis, C Fischer, J Grimm, ... US Patent 9,290,490, 2016 | 15 | 2016 |
| Pyrazolyl derivatives as Syk inhibitors MR Machacek, MD Altman, ET Romeo, D Vitharana, B Cash, T Siu, ... US Patent 9,242,984, 2016 | 15 | 2016 |
| Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors A Gulati, CS Yeung, B Lapointe, SD Kattar, H Gunaydin, JD Scott, ... RSC Medicinal Chemistry 12 (7), 1164-1173, 2021 | 14 | 2021 |
| Substituted diazine and triazine spleen tyrosine kinease (Syk) inhibitors AM Haidle, MD Altman, SD Kattar, M Christopher, JM Ellis, C Fischer, ... US Patent 9,416,111, 2016 | 13 | 2016 |
