A trip to the ER: coping with stress DT Rutkowski, RJ Kaufman Trends in cell biology 14 (1), 20-28, 2004 | 1782 | 2004 |
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins DT Rutkowski, SM Arnold, CN Miller, J Wu, J Li, KM Gunnison, K Mori, ... PLoS biology 4 (11), e374, 2006 | 958 | 2006 |
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response K Zhang, X Shen, J Wu, K Sakaki, T Saunders, DT Rutkowski, SH Back, ... Cell 124 (3), 587-599, 2006 | 956 | 2006 |
ATF6α optimizes long-term endoplasmic reticulum function to protect cells from chronic stress J Wu, DT Rutkowski, M Dubois, J Swathirajan, T Saunders, J Wang, ... Developmental cell 13 (3), 351-364, 2007 | 812 | 2007 |
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators DT Rutkowski, J Wu, SH Back, MU Callaghan, SP Ferris, J Iqbal, R Clark, ... Developmental cell 15 (6), 829-840, 2008 | 672 | 2008 |
That which does not kill me makes me stronger: adapting to chronic ER stress DT Rutkowski, RJ Kaufman Trends in biochemical sciences 32 (10), 469-476, 2007 | 514 | 2007 |
Regulation of basal cellular physiology by the homeostatic unfolded protein response DT Rutkowski, RS Hegde Journal of Cell Biology 189 (5), 783-794, 2010 | 458 | 2010 |
The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex J Wu, JL Ruas, JL Estall, KA Rasbach, JH Choi, L Ye, P Boström, HM Tyra, ... Cell metabolism 13 (2), 160-169, 2011 | 380 | 2011 |
The Role of p58IPK in Protecting the Stressed Endoplasmic Reticulum DT Rutkowski, SW Kang, AG Goodman, JL Garrison, J Taunton, MG Katze, ... Molecular biology of the cell 18 (9), 3681-3691, 2007 | 257 | 2007 |
All roads lead to ATF4 DT Rutkowski, RJ Kaufman Developmental cell 4 (4), 442-444, 2003 | 237 | 2003 |
Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway IH Hassan, MS Zhang, LS Powers, JQ Shao, J Baltrusaitis, DT Rutkowski, ... Journal of Biological Chemistry 287 (7), 4679-4689, 2012 | 180 | 2012 |
Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS J Wang, GW Farr, CJ Zeiss, DJ Rodriguez-Gil, JH Wilson, K Furtak, ... Proceedings of the National Academy of Sciences 106 (5), 1392-1397, 2009 | 178 | 2009 |
C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver MR Chikka, DDZ McCabe, HM Tyra, DT Rutkowski Journal of biological chemistry 288 (6), 4405-4415, 2013 | 124 | 2013 |
ER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis D DeZwaan-McCabe, RD Sheldon, MC Gorecki, DF Guo, ER Gansemer, ... Cell reports 19 (9), 1794-1806, 2017 | 102 | 2017 |
Regulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences AM Arensdorf, D Diedrichs, DT Rutkowski Frontiers in genetics 4, 256, 2013 | 99 | 2013 |
The stress-regulated transcription factor CHOP promotes hepatic inflammatory gene expression, fibrosis, and oncogenesis D DeZwaan-McCabe, JD Riordan, AM Arensdorf, MS Icardi, AJ Dupuy, ... PLoS genetics 9 (12), e1003937, 2013 | 91 | 2013 |
Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen DT Rutkowski, CM Ott, JR Polansky, VR Lingappa Journal of Biological Chemistry 278 (32), 30365-30372, 2003 | 87 | 2003 |
Substrate-specific regulation of the ribosome–translocon junction by N-terminal signal sequences DT Rutkowski, VR Lingappa, RS Hegde Proceedings of the National Academy of Sciences 98 (14), 7823-7828, 2001 | 86 | 2001 |
2-Deoxyglucose-induced toxicity is regulated by Bcl-2 family members and is enhanced by antagonizing Bcl-2 in lymphoma cell lines O Zagorodna, SM Martin, DT Rutkowski, T Kuwana, DR Spitz, ... Oncogene 31 (22), 2738-2749, 2012 | 81 | 2012 |
NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum homeostasis ER Gansemer, KS McCommis, M Martino, AQ King-McAlpin, MJ Potthoff, ... Iscience 23 (5), 2020 | 69 | 2020 |